Hydrophilic (η<sup>6</sup>-Arene)–Ruthenium(II) Complexes with P–OH Ligands as Catalysts for the Isomerization of Allylbenzenes and C–H Bond Arylation Reactions in Water
Half-sandwich ruthenium(II) complexes containing η6-coordinated 3-phenylpropanol and phosphinous-acid-type ligands, namely, [RuCl2(η6-C6H5CH2CH2CH2OH)P(OH)R2}] (R = Me (2a), Ph (2b), 4-C6H4CF3 (2c), 4-C6H4OMe (2d), OMe (2e), OEt (2f), and OPh (2g), have been synthesized in 44–88% yield by reacting [RuCl2η6:κ1(O)-C6H5CH2CH2CH2OH}] (1) with the appropriate pentavalent phosphorus oxide R2P(═O)H. The
含η半夹心钌(II)配合物6配位的3-苯基丙醇和亚膦酸基型配体,即,将[RuCl 2(η 6 -C 6 H ^ 5 CH 2 CH 2 CH 2 OH)P(OH) R 2 }](R = Me(2a),Ph(2b),4-C 6 H 4 CF 3(2c),4-C 6 H 4 OMe(2d),OMe(2e),OEt(2f),和OPh(2克),已在44-88%的产率通过反应而合成将[RuCl 2 η 6:κ 1(Ò)-C 6 H ^ 5 CH 2 CH 2 CH 2 OH}](1)与适当的五价磷氧化物R 2 P(= O)H。的结构将[RuCl 2(η 6 -C 6 H ^ 5 CH 2 CH 2 CH 2 OH)P(OH)Me 2 }](2A)通过X射线衍射方法进行了明确地证实。化合物2a – g被证明是催化活性在allylbenzenes的异构化为相应的(1-丙烯基)采用水作为唯一的反应溶剂,用将[RuCl苯衍生物2(η
RuCl<sub>3</sub>⋅<i>x</i> H<sub>2</sub>O-Catalyzed Direct Arylation of Arenes with Aryl Chlorides in the Presence of Triphenylphosphine
作者:Ning Luo、Zhengkun Yu
DOI:10.1002/chem.200902612
日期:2010.1.18
A simple, efficient, and economically attractive catalytic system has been developed for the directarylation of arenes with arylchlorides with the RuCl3⋅xH2O/PPh3/Na2CO3/N‐methyl‐2‐pyrrolidone system (see scheme). A remarkable effect of the nature of the base was observed, with Na2CO3 giving the best results.
一个简单的,高效和经济上有吸引力的催化体系已被开发用于芳烃的与和的RuCl芳基氯的直接芳基化3 ⋅ X ħ 2 O / PPH 3 /钠2 CO 3 / Ñ甲基-2-吡咯烷酮系统(参见方案)。观察到了碱性质的显着影响,其中Na 2 CO 3给出了最佳结果。
Acetamide as Cocatalyst for the Nitrogen-Directed Coupling of Arenes with Aryl Chlorides through Ruthenium-Catalyzed C-H Activation
作者:Jie Zhang、Qin Yang、Zhu Zhu、Mao Lin Yuan、Hai Yan Fu、Xue Li Zheng、Hua Chen、Rui Xiang Li
DOI:10.1002/ejoc.201201127
日期:2012.12
by C–H activation is described. Acetamide was found to be an effective cocatalyst for this generally applicable ruthenium(II)-catalyzed direct arylation reaction. A wide range of deactivated aryl chlorides could be efficiently coupled under the mild temperature of 101 °C. The new process is highly atom-economical and sustainable.
描述了一种通过 C-H 活化交叉偶联芳烃的简单高效的方法。发现乙酰胺是这种普遍适用的钌 (II) 催化的直接芳基化反应的有效助催化剂。在 101 °C 的温和温度下,可以有效地偶联多种失活的芳基氯。新工艺具有高度的原子经济性和可持续性。
Combination of RuCl<sub>3</sub>·xH<sub>2</sub>O with PEG – a simple and recyclable catalytic system for direct arylation of heteroarenes via C–H bond activation
作者:Lei Jian、Hai-Yu He、Jin Huang、Qian-Hui Wu、Mao-Lin Yuan、Hai-Yan Fu、Xue-Li Zheng、Hua Chen、Rui-Xiang Li
DOI:10.1039/c7ra02638b
日期:——
A simple and recyclable catalytic system for directarylation of heteroarenes via C–H bond activation was developed with a relatively inexpensive RuCl3·xH2O as a catalyst and PEG-400 as a green medium without any additive or ligand. This system not only showed excellent functional group compatibility, but also the ratio of mono- to diarylated product was easily regulated by varying the reaction conditions
通过使用相对便宜的RuCl 3 · x H 2 O作为催化剂和PEG-400作为绿色介质,没有任何添加剂或配体,开发了一种简单且可回收的催化系统,用于通过C–H键活化杂芳烃直接芳基化。该体系不仅显示出优异的官能团相容性,而且通过改变反应条件也很容易调节单芳基化产物与二芳基化产物的比例。而且,该转化可以在空气中进行,并且在0.3mol%的低催化剂负载下可以容易地按比例放大至克级。特别地,在将该催化剂循环六次之后,获得了85%的良好产率。
Synthesis of Cationic Azatriphenylene Derivatives by Electrochemical Intramolecular Pyridination and Characterization of Their Optoelectronic Properties
Here, a facile and selective synthesismethod for cationic azatriphenylene derivatives was established by electrochemical intramolecular cyclization, where atom-economical C–H pyridination without a transition-metal catalyst or an oxidant is a keystep. The proposed protocol is a practical strategy for the late-stage introduction of cationic nitrogen (N+) into π-electron systems and broadens the scope
在这里,通过电化学分子内环化建立了一种简便且选择性的阳离子氮杂苯并菲衍生物合成方法,其中没有过渡金属催化剂或氧化剂的原子经济 C-H 吡啶化是关键步骤。所提出的协议是将阳离子氮 ( N + )后期引入 π 电子系统的实用策略,并拓宽了N +掺杂多环芳烃的分子设计范围。