N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide | 245125-71-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide
• 英文别名: N-[diethylamino-(2-diphenylphosphanylphenyl)phosphanyl]-N-ethylethanamine
• CAS: 245125-71-7
• 化学式: C₂₆H₃₄N₂P₂
• 分子量: 436.517
• InChiKey: IPIAMVQVDRBBFD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  30
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide 在 盐酸 作用下， 以 乙醚 为溶剂， 以98%的产率得到[2-(二苯基膦基)苯基]亚膦酸二氯化物
  参考文献：
  名称：

  New non-C2-symmetric phosphine-phosphonites as ligands in asymmetric metal catalysis

  摘要：

  Starting from 1,2-dibromobenzene, the synthesis of N,N,N'-N'-tetraethyl-[2-(diphenylphosphino)phenyl]phosphonous acid tetraamide is possible in two simple steps. This key compound reacts with a variety of chiral diols such as (R)- and (S)-binaphthol, 1,2:5,6-diisapropylidene-D-mannitol or (1R,2R)-1,2-diphenyl-1,2-ethane diol to form the corresponding non-C-2-symmetric phosphine-phosphonite compounds. These ligands react with Rh(COD)(2)BF4 to form bidentate Rh-complexes which serve as catalysts in the asymmetric hydrogenation of dimethyl itaconate with ee values of up to 88%. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(99)00215-3
• 作为产物：
  描述：

  1,2-二溴苯 在 正丁基锂 作用下， 反应 0.83h， 生成 N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide
  参考文献：
  名称：

  New non-C2-symmetric phosphine-phosphonites as ligands in asymmetric metal catalysis

  摘要：

  Starting from 1,2-dibromobenzene, the synthesis of N,N,N'-N'-tetraethyl-[2-(diphenylphosphino)phenyl]phosphonous acid tetraamide is possible in two simple steps. This key compound reacts with a variety of chiral diols such as (R)- and (S)-binaphthol, 1,2:5,6-diisapropylidene-D-mannitol or (1R,2R)-1,2-diphenyl-1,2-ethane diol to form the corresponding non-C-2-symmetric phosphine-phosphonite compounds. These ligands react with Rh(COD)(2)BF4 to form bidentate Rh-complexes which serve as catalysts in the asymmetric hydrogenation of dimethyl itaconate with ee values of up to 88%. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(99)00215-3

文献信息

• Highly efficient asymmetric (diphenylphosphino)benzene‐based chromium catalysts for selective ethylene trimerization
  作者：Jing Ma、Haonan Fan、Biaobiao Hao、Tao Jiang

  DOI：10.1002/aoc.6907

  日期：2022.12

  The corresponding Cr(III) catalysts (1–6) based on asymmetric (diphenylphosphino)benzene-type L1–L6 ligands have been explored for ethylene selective trimerization. It is observed that the structure of the complexes has an obvious influence on their catalytic performance for ethylene selective oligomerization. All the 1–6 precatalysts may offer selective ethylene trimerization systems, and their catalytic

  已经探索了基于不对称（二苯基膦基）苯型L 1 -L 6配体的相应 Cr(III) 催化剂 ( 1-6 ) 用于乙烯选择性三聚。观察到配合物的结构对其催化乙烯选择性齐聚的性能有明显的影响。所有1-6种预催化剂都可以提供选择性的乙烯三聚体系，其催化性能受反应条件的影响很大。带有二异丙基膦基取代基的预催化剂2可以表现出 90.4% C 6的 9.83 × 10 7  g/(molCr·h)的显着高催化活性合适条件下的选择性。单晶X射线分析表明，配体的烷基/烷基氨基膦基可以有效地调节催化剂结构，从而影响低聚活性和产物选择性。
• KYBA, E. P.;KERBY, M. C.;RINES, S. P., ORGANOMETALLICS, 1986, 5, N 6, 1189-1194
  作者：KYBA, E. P.、KERBY, M. C.、RINES, S. P.

  DOI：——

  日期：——
• New non-C2-symmetric phosphine-phosphonites as ligands in asymmetric metal catalysis
  作者：Manfred T Reetz、Andreas Gosberg

  DOI：10.1016/s0957-4166(99)00215-3

  日期：1999.6

  Starting from 1,2-dibromobenzene, the synthesis of N,N,N'-N'-tetraethyl-[2-(diphenylphosphino)phenyl]phosphonous acid tetraamide is possible in two simple steps. This key compound reacts with a variety of chiral diols such as (R)- and (S)-binaphthol, 1,2:5,6-diisapropylidene-D-mannitol or (1R,2R)-1,2-diphenyl-1,2-ethane diol to form the corresponding non-C-2-symmetric phosphine-phosphonite compounds. These ligands react with Rh(COD)(2)BF4 to form bidentate Rh-complexes which serve as catalysts in the asymmetric hydrogenation of dimethyl itaconate with ee values of up to 88%. (C) 1999 Elsevier Science Ltd. All rights reserved.