[CuCl₂(PPh₃)₂] | 38613-49-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [CuCl₂(PPh₃)₂]
• 英文别名: (Cu(PPh₃)₂Cl₂)；Dichlorocopper;triphenylphosphane；dichlorocopper;triphenylphosphane
• CAS: 38613-49-9
• 化学式: C₃₆H₃₀Cl₂CuP₂
• 分子量: 659.034
• InChiKey: PKFFOSMUGKOUQN-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  8.27
• 重原子数：
  41
• 可旋转键数：
  6
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  [CuCl₂(PPh₃)₂] 、 2-(5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)phenol 在 sodium hydroxide 作用下， 以 甲醇 为溶剂， 反应 4.5h， 以68%的产率得到bis(salicylidene)hydrazone binuclear copper(I) complex
  参考文献：
  名称：

  Heteroleptic binuclear copper(I) complexes bearing bis(salicylidene)hydrazone ligands: Synthesis, crystal structure and application in catalytic N-alkylation of amines

  摘要：

  A new series of heteroleptic binuclear Cu(I) bis(salicylidene)hydrazone complexes (1-4) bearing triphenylphospine coligands have been synthesized from the reactions of copper(II) precursor complex [CuCl2(PPh3)(2)] with oxadiazole compounds A-D, respectively. It has been observed that the oxadiazole compounds u ndergo ring cleavage with in situ reduction of Cu(II) ion, during the formation of complexes (1-4). The oxadiazoles (A-D) and the Cu(I) complexes (1-4) have been characterized by analytical and spectroscopic methods. Single crystal X-ray diffraction study of complex 2 has revealed a distorted tetrahedral geometry around each Cu(I) center. Catalytic efficiency of the new complexes on the N-alkylation of amines using alcohols was studied under optimized conditions. The new complexes have also been tested for their catalytic activity towards the direct N-alkylation of 2-nitropyridine. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2014.12.015
• 作为产物：
  描述：

  三苯基膦 、 copper dichloride 以 乙醇 为溶剂， 生成 [CuCl₂(PPh₃)₂]
  参考文献：
  名称：

  固态复分解中Lewis碱通过原子转移介导黄铁矿CuSe 2的多晶型选择性

  摘要：

  传统固态化学的局限性（即诱导固态扩散所需的高温）常常阻碍了亚稳态固态材料的制备。在这里，我们介绍了由路易斯碱介导的三苯膦（Ph 3 P）介导的易位反应，形成了CuSe 2的亚稳黄铁矿多晶型物。添加到双盐交换反应CuCl 2 + Na 2 Se 2中的Ph 3 P从前体中提取硒，并在130–150°C（而不是纯反应混合物所需的300°C）下促进反应。粉末X射线衍射实验表明，亚化学计量的磷化氢生成黄铁矿CuSe 2; 红外光谱和核磁共振光谱以及质谱证实了Ph 3 PSe和Cu（Ph 3 P）n +加合物的形成，这暗示了Lewis碱有助于原子转移反应，从而降低了形成亚稳态的活化势垒CuSe 2的黄铁矿多晶型。这些结果提供了一种用于材料合成的新化学方法的实例，该方法将能够合成新的亚稳态晶体材料。

  DOI：

  10.1021/acs.chemmater.6b00027

文献信息

• Synthesis, Characterization and Biological Evaluation of Metal(II) Complexes Containing Triphenylphosphine and Schiff Base Ligand Based on 3-Methoxysalicylaldehyde
  作者：G. Gokulnath、P. Anitha、R. Manikandan、C. Umarani

  DOI：10.14233/ajchem.2021.23262

  日期：——

  Schiff base ligand (HL) derived from condensation of 3-methoxy salicylaldehyde with 4-aminobenzoic acid and its metal(II) complexes containing triphenylphosphine of the type [MCl(PPh3)(L)] (M = Ni2+, Co2+ or Cu2+; L = bitendate Schiff base ligand) have been synthesized. All the metal(II) complexes were characterized by analytical and spectroscopic (FT-IR, electronic, ESI-Mass, ESR, 1H, 13C NMR and 31P NMR) techniques. All the synthesized compounds were evaluated for in vitro antimicrobial efficiency against Gram-positive bacteria, Gram-negative bacteria and fungai using the agar well diffusion method. Anticancer activity in vitro of the ligand and its metal(II) complexes were also screened against MCF-7 cancer cell lines (human breast cancer cell line).

  Schiff碱配体（HL）是由3-甲氧基水杨醛与4-氨基苯甲酸缩合而成的，其金属（II）配合物含有三苯基膦，类型为[MCl（PPh3）（L）]（M = Ni2+，Co2+或Cu2+；L = 双齿Schiff碱配体）。所有金属（II）配合物均通过分析和光谱（FT-IR，电子，ESI-质谱，ESR，1H，13C NMR和31P NMR）技术进行了表征。所有合成的化合物均通过琼脂孔扩散法评估了其对革兰氏阳性细菌、革兰氏阴性细菌和真菌的体外抗菌效果。体外抗癌活性也对配体及其金属（II）配合物针对MCF-7癌细胞系（人类乳腺癌细胞系）进行了筛选。
• Catalytic one-pot three-component synthesis of 3,3′-disubstituted oxindoles and spirooxindole pyrans by mixed ligand transition metal complexes
  作者：Sujit Hegade、Gautam Gaikwad、Yuvraj Jadhav、Avinash Pore、Abhijeet Mulik

  DOI：10.1007/s00706-021-02867-8

  日期：2022.1

  Abstract New three-component reaction was developed via one-pot strategy for the synthesis of functionalized 3,3′-disubstituted oxindoles and spirooxindole through the reaction among isatin, malononitrile, and acetone/indole/nitromethane/acetylacetone/dimedone in ethanol as solvent without base. It was observed that all the mixed ligand transition metal complexes with triphenylphosphine worked as the

  摘要 通过一锅法开发了新的三组分反应，通过靛红、丙二腈和丙酮/吲哚/硝基甲烷/乙酰丙酮/二甲酮在无碱乙醇溶剂中的反应合成功能化的 3,3'-二取代羟吲哚和螺吲哚. 观察到所有与三苯基膦的混合配体过渡金属配合物均作为有效催化剂起作用。本方法具有几个优点，包括催化剂的制备和处理简单，后处理简单易行，反应时间短，产物收率高。 图形概要
• Monodentate coordination of N-[di(phenyl/ethyl)carbamothioyl]benzamide ligands: synthesis, crystal structure and catalytic oxidation property of Cu(i) complexes
  作者：Nanjappan Gunasekaran、Pandian Ramesh、Mondikalipudur Nanjappa Gounder Ponnuswamy、Ramasamy Karvembu

  DOI：10.1039/c1dt10628g

  日期：——

  New four-coordinated tetrahedral copper(I) complexes have been synthesized from the reactions between [CuCl2(PPh3)2] and N-(diphenylcarbamothioyl)benzamide (HL1) or N-(diethylcarbamothioyl)benzamide (HL2) in benzene. These complexes have been characterized by elemental analyses, IR, UV/Vis, 1H, 13C and 31P NMR spectroscopy. The molecular structure of both the complexes, [CuCl(HL1)2(PPh3)] (1) and [CuCl(HL2)(PPh3)2] (2) were determined by single-crystal X-ray diffraction, which reveals distorted tetrahedral geometry around each Cu(I) ion. The combination of 2 (0.005 mmol) with hydrogen peroxide (2.5 mmol) in acetonitrile is found to be an active catalyst for the oxidation of primary and secondary alcohols (0.5 mmol) to their corresponding acids and ketones, respectively, at room temperature.

  新的四配位四面体铜(I)配合物是通过在苯中将[CuCl2(PPh3)2]与N-(二苯基氨硫酰)苯胺（HL1）或N-(二乙基氨硫酰)苯胺（HL2）反应合成的。这些配合物通过元素分析、红外光谱、紫外/可见光谱、1H、13C和31P NMR光谱进行了表征。两个配合物[CuCl(HL1)2(PPh3)]（1）和[CuCl(HL2)(PPh3)2]（2）的分子结构通过单晶 X 射线衍射确定，结果显示每个Cu(I)离子周围具有扭曲的四面体几何形状。将2（0.005 mmol）与过氧化氢（2.5 mmol）在乙腈中组合发现是一种活性催化剂，能在室温下将初级和次级醇（0.5 mmol）氧化为相应的酸和酮。
• Synthesis, characterization and catalytic oxidation property of copper(I) complexes containing monodentate acylthiourea ligands and triphenylphosphine
  作者：N. Gunasekaran、N.S.P. Bhuvanesh、R. Karvembu

  DOI：10.1016/j.poly.2016.10.038

  日期：2017.1

  4-dichlorobenzoyl)thiourea (HL3) in benzene gave new four-coordinated tetrahedral copper(I) complexes of the type [CuCl(HL)(PPh3)2] (1–3) [HL = 3,3-dialkyl/aryl-1-(2,4-dichlorobenzoyl)thiourea derivatives]. These complexes were then characterized by analytical and spectroscopic (IR, UV/Vis, 1H, 13C and 31P NMR) techniques. The molecular structure of a representative complex, [CuCl(HL1)(PPh3)2] (1), was determined

  摘要[CuCl2（PPh3）2]与3,3-二苯基-1-（2,4-二氯苯甲酰基）硫脲（HL1），3,3-二异丁基-1-（2,4-二氯苯甲酰基）硫脲（HL2）之间的反应）或苯中的3,3-二乙基-1-（2,4-二氯苯甲酰基）硫脲（HL3）得到新的四配位四面体铜（I）络合物，类型为[CuCl（HL）（PPh3）2]（1– 3）[HL ＝ 3，3-二烷基/芳基-1-（2，4-二氯苯甲酰基）硫脲衍生物]。然后通过分析和光谱（IR，UV / Vis，1H，13C和31P NMR）技术对这些配合物进行表征。通过单晶X射线衍射方法确定了代表性配合物[CuCl（HL1）（PPh3）2]（1）的分子结构，该方法揭示了Cu（I）离子周围的四面体几何形状失真。发现配合物1-3（0.007 mmol）是伯和仲醇5氧化的活性催化剂。
• A catalytic process for the selective oxidation of alcohols by copper (II) complexes
  作者：Dileep Ramakrishna、Badekai Ramachandra Bhat

  DOI：10.1016/j.inoche.2011.02.007

  日期：2011.5

  Abstract Novel copper (II)–N–(2-pyridyl)–N'–(5-R-salicylidene) hydrazine triphenylphosphine complexes have been synthesized and characterized. The complexes were effective in the catalytic oxidation of primary and secondary alcohols in presence of periodic acid (H5IO6) as oxidant. The oxidation reactions were carried out in acetonitrile. Electrochemical electron transfer study reveals CuII–CuI reduction

  摘要 合成并表征了新型铜 (II)-N-(2-吡啶基)-N'-(5-R-水杨基)肼三苯基膦配合物。在作为氧化剂的高碘酸 (H5IO6) 存在下，该配合物可有效催化氧化伯醇和仲醇。氧化反应在乙腈中进行。电化学电子转移研究揭示了甲醇溶液中的 CuII-CuI 还原。已经提出了对上述反应的机理研究。