(1S,3S)-1-phenylpentan-1,3-diol | 1447712-85-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (1S,3S)-1-phenylpentan-1,3-diol
• 英文别名: (1S,3S)-1-phenylpentane-1,3-diol
• CAS: 1447712-85-7
• 化学式: C₁₁H₁₆O₂
• 分子量: 180.247
• InChiKey: BOIHAPODUXHNBA-QWRGUYRKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (1S,3S)-1-phenylpentan-1,3-diol 、 甲氧基-三氟甲基苯 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 反应 96.0h， 以1.3 mg的产率得到
  参考文献：
  名称：

  Rare 2-phenylpyran-4-ones from the seagrass-derived fungi Polyporales PSU-ES44 and PSU-ES83

  摘要：

  Eight new 2-phenylpyranon-4-one derivatives, polyporapyranones A-H (1-8), together with eight known compounds were isolated from two seagrass-derived fungi Polyporales PSU-ES44 and PSU-ES83. Their structures were determined by spectroscopic methods. 2-Phenylpyran-4-one derivatives are rare natural products. Some isolated compounds were evaluated for cytotoxic activity against human breast cancer (MCF-7) and noncancerous Vero (African green monkey kidney fibroblasts) cell lines. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.06.059

文献信息

• Rare 2-phenylpyran-4-ones from the seagrass-derived fungi Polyporales PSU-ES44 and PSU-ES83
  作者：Vatcharin Rukachaisirikul、Sirikan Kannai、Saranyoo Klaiklay、Souwalak Phongpaichit、Jariya Sakayaroj

  DOI：10.1016/j.tet.2013.06.059

  日期：2013.8

  Eight new 2-phenylpyranon-4-one derivatives, polyporapyranones A-H (1-8), together with eight known compounds were isolated from two seagrass-derived fungi Polyporales PSU-ES44 and PSU-ES83. Their structures were determined by spectroscopic methods. 2-Phenylpyran-4-one derivatives are rare natural products. Some isolated compounds were evaluated for cytotoxic activity against human breast cancer (MCF-7) and noncancerous Vero (African green monkey kidney fibroblasts) cell lines. (C) 2013 Elsevier Ltd. All rights reserved.