2-thioxo-2,3-dihydro-benzothiazole-5-sulfonic acid | 23015-22-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 英文名称: 2-thioxo-2,3-dihydro-benzothiazole-5-sulfonic acid
• 英文别名: 2-Thioxo-2,3-dihydro-benzothiazol-5-sulfonsaeure；2-Sulfanyl-1,3-benzothiazole-5-sulfonic acid；2-sulfanylidene-3H-1,3-benzothiazole-5-sulfonic acid
• CAS: 23015-22-7
• 化学式: C₇H₅NO₃S₃
• 分子量: 247.32
• InChiKey: YOPUIFSTGVXMLL-UHFFFAOYSA-N

物化性质

• 密度：
  1.88±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  132
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-thioxo-2,3-dihydro-benzothiazole-5-sulfonic acid 在 sodium hydroxide 、 sodium hypochlorite 作用下， 生成 benzothiazole-2,5-disulfonic acid
  参考文献：
  名称：

  US2018813

  摘要：

  公开号：
• 作为产物：
  描述：

  二硫化碳 、 4-溴-3-硝基苯磺酸 在 sodium hydrogensulfide 作用下， 生成 2-thioxo-2,3-dihydro-benzothiazole-5-sulfonic acid
  参考文献：
  名称：

  Teppema; Sebrell, Journal of the American Chemical Society, 1927, vol. 49, p. 1757

  摘要：

  DOI：

文献信息

• LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING PROCESS
  申请人：OOHASHI Hidekazu

  公开号：US20110054212A1

  公开（公告）日：2011-03-03

  A lithographic printing plate precursor, which comprises: a support; an image-recording layer; and a protective layer, in this order, wherein at least one of the image-recording layer and the protective layer comprises a phosphonium salt having a specific structure, and a lithographic printing process, which comprises: exposing a lithographic printing plate precursor; supplying an oil-based ink and a fountain solution comprising a phosphonium salt having a specific structure to the exposed lithographic printing plate precursor on a printing machine to remove an unexposed area of an image-recording layer; and conducting printing.

  一种光刻印刷版前体，包括：支撑体；图像记录层；以及保护层，依次排列，其中图像记录层和保护层中至少有一层包含具有特定结构的磷酸铵盐；以及一种光刻印刷工艺，包括：曝光光刻印刷版前体；在印刷机上向曝光的光刻印刷版前体提供具有特定结构的磷酸铵盐的油墨和喷泉溶液，以去除图像记录层中未曝光区域；进行印刷。
• Lithographic printing plate precursor and lithographic printing process
  申请人：Fuji Photo Film Co., Ltd.

  公开号：EP1754597A2

  公开（公告）日：2007-02-21

  A lithographic printing plate precursor, which comprises: a support; an image-recording layer; and a protective layer, in this order, wherein at least one of the image-recording layer and the protective layer comprises a phosphonium salt having a specific structure, and a lithographic printing process, which comprises: exposing a lithographic printing plate precursor; supplying an oil-based ink and a fountain solution comprising a phosphonium salt having a specific structure to the exposed lithographic printing plate precursor on a printing machine to remove an unexposed area of an image-recording layer; and conducting printing.

  一种平版印刷板前体，它依次包括：支撑物；图像记录层；和保护层，其中图像记录层和保护层中的至少一个包括具有特定结构的膦盐，以及一种平版印刷工艺，它包括：曝光平版印刷板前体；在印刷机上向曝光的平版印刷板前体提供油基油墨和包含具有特定结构的鏻盐的润版液，以去除图像记录层的未曝光区域；以及进行印刷。
• Methods and apparatus for accelerated orthokeratology
  申请人：——

  公开号：US20010016731A1

  公开（公告）日：2001-08-23

  An accelerated method of orthokeratology includes the steps of softening of the cornea with a softening agent, applying a mold to reshape the cornea to a desired anterior curvature, and rapidly restabilizing or “fixing” the corneal tissues so that the cornea retains its new configuration. A chemical softening agent, such as glutaric anhydride is applied to the cornea to soften the cornea, after which a specially designed mold of predetermined curvature and configuration is applied to the cornea. Slight downward pressure is applied to the mold for a predetermined period of time to re-shape the cornea. The mold is maintained in position while a stabilizing agent, such as a UV light source, is positioned above the mold. The stabilizing agent, i.e. UV light, is applied to the cornea for a predetermined time, wherein the stabilizing agent immediately restabilizes the corneal tissue so that the cornea immediately retains its shape upon removal of the mold. The stabilization process can also be used for patients having already undergone traditional orthokeratology to eliminate the need to continue wearing a retainer to maintain the shape of the cornea.

  角膜矫形术的加速方法包括以下步骤：用软化剂软化角膜，使用模具将角膜重塑成所需的前弧度，并迅速重新稳定或 "固定 "角膜组织，使角膜保持新的形态。在角膜上涂抹化学软化剂（如戊二酸酐）以软化角膜，然后在角膜上涂抹专门设计的具有预定弧度和结构的模具。在预定时间内对模具施加轻微的向下压力，以重新塑形角膜。将稳定剂（如紫外线光源）置于模具上方时，模具将保持在原位。将稳定剂（即紫外线）照射到角膜上，持续预定的时间，其中稳定剂会立即重新稳定角膜组织，使角膜在移除模具后立即保持其形状。稳定过程也可用于已接受传统角膜矫形术的患者，使其无需继续佩戴保持器来保持角膜的形状。
• DE615132
  申请人：——

  公开号：——

  公开（公告）日：——
• METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY
  申请人：Ista Pharmaceuticals, Inc.

  公开号：EP1051655A1

  公开（公告）日：2000-11-15