Phosphorsaeure-(2-hydroxy-ethyl)-phenylester | 46338-51-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Phosphorsaeure-(2-hydroxy-ethyl)-phenylester
• 英文别名: (2-Hydroxy-ethyl)-phenyl-phosphat；2-Hydroxyethyl phenyl hydrogen phosphate
• CAS: 46338-51-6
• 化学式: C₈H₁₁O₅P
• 分子量: 218.146
• InChiKey: FOUBDYCNVLPXFV-UHFFFAOYSA-N

物化性质

• 沸点：
  366.5±44.0 °C(Predicted)
• 密度：
  1.403±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2-phenoxy-[1,3,2]dioxaphospholane 2-oxide 在 碳酸氢钠 作用下， 生成 Phosphorsaeure-(2-hydroxy-ethyl)-phenylester
  参考文献：
  名称：

  环状有机磷化合物。第六部分 在碱-二恶烷水溶液中水解一些1,3,2-二氧杂膦酸酯和1,3,2-二氧杂膦酸酯

  摘要：

  对于化合物在氢氧化钠水溶液中的溶液，逐步地用甲基取代2-硫代-1,3,2-二氧杂膦酰基环系统中位置4和5的氢原子，使该环稳定在一个恒定的2倍左右的常数下。 –二恶英。认为该作用是由于电子相互作用而不是空间相互作用，并且比与磷连接的环外基团产生的作用弱得多。在所采用的条件下，2-氧代-2-苯氧基-和2-乙氧基-4,4,5,5-四甲基-2-硫醇-1,3,2-二氧杂膦酰基酯主要产生开环产物。

  DOI：

  10.1039/j29670000577

文献信息

• DENTAL RESTORATIVE MATERIAL
  申请人：Tokuyama Dental Corporation

  公开号：EP2724706A1

  公开（公告）日：2014-04-30

  The present invention discloses a dental restorative material comprising 10-50 mass% of (A) a polymerizable monomer, 5-80 mass% of (B)an organic-inorganic composite filler which is prepared by dispersing an inorganic fine filler having an average particle diameter of 1 µm or smaller in an organic matrix and has an average particle diameter of 5.0-50 µm, and 10-60 mass% of (C) a third component, i.e., an inorganic filler having an average particle diameter of 1.1-5.0 µm, wherein the absolute value of the difference between the refractive index [nC] of the inorganic filler (C) and the refractive index [nB] of the organic-inorganic composite filler (B)(i.e., |nC-nB|) is 0.005-0.07 at 32°C and the absolute value of the difference between the refractive index [nA] of the cured product of the polymerizable monomer (A) and the refractive index [nC] of the inorganic filler (C) (i.e., |nA-nC|) is 0.005-0.05 at 32°C.

  本发明公开了一种牙科修复材料，包括 10-50 质量％的(A)可聚合单体、5-80 质量％的(B)有机-无机复合填料，该填料是通过在有机基质中分散平均颗粒直径为 1 微米或更小的无机精细填料制备而成，其平均颗粒直径为 5.0-50 微米；以及 10-60 质量％的(C)第三组分，即平均颗粒直径为 1.1-5.0 微米的无机填料、其中无机填料 (C) 的折射率[nC]与有机-无机复合填料 (B) 的折射率[nB]之差的绝对值（即、在 32°C 时，|nC-nB|）的绝对值为 0.005-0.07；在 32°C 时，可聚合单体（A）固化产物的折射率[nA]与无机填料（C）的折射率[nC]之差（即|nA-nC|）的绝对值为 0.005-0.05。
• Rueger, C.; Koenig, T.; Schwetlick, K., Journal fur praktische Chemie (Leipzig 1954), 1984, vol. 326, # 4, p. 622 - 632
  作者：Rueger, C.、Koenig, T.、Schwetlick, K.

  DOI：——

  日期：——
• KONIG T.; GROSSMANN G.; SCHWETLICK K.; RUGER C., J. PRAKT. CHEM., 328,(1986) N 5-6, 763-771
  作者：KONIG T.、 GROSSMANN G.、 SCHWETLICK K.、 RUGER C.

  DOI：——

  日期：——
• Rapid nucleic acid isolation method and compositions
  申请人：Hossain Ashfaque

  公开号：US20070077562A1

  公开（公告）日：2007-04-05

  A method of isolating RNA from a biological specimen is provided, whereby a biological specimen is contacted with an admixture of (i) a mono-phasic solution of phenol and guanidine isothiocyanate and (ii) a lysis buffer under conditions and for a time appropriate to form a homogenate. Next, the homogenate is admixed with a water-immiscible organic solvent under conditions and for a time appropriate to form an aqueous phase and an organic phase. The aqueous phase is then contacted with a C 1 -C 4 lower alcohol under conditions and for a time to form a precipitated RNA. The precipitated RNA is then recovered by centrifugation and decanting of the aqueous phase. The method can also be used to isolate total RNA. In an alternative embodiment, the biological sample is contacted with (i) a lysis buffer, and (ii) a mono-phasic solution of phenol and guanidine isothiocyanate under conditions and for a time appropriate to form a homogenate. The remaining steps of this embodiment are the same as above.
• US8062845B2
  申请人：——

  公开号：US8062845B2

  公开（公告）日：2011-11-22