(Z)-1-deuterio-3,3-dimethyl-1-phenyl-1-butene | 23586-62-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (Z)-1-deuterio-3,3-dimethyl-1-phenyl-1-butene
• 英文别名: 1-deuterio-3,3-dimethyl-1-phenyl-1-butene；cis-3,3-Dimethyl-1-phenyl-1-deuterio-buten-(1)；(Z)-α-Deuterio-β-t-butylstyrol；[(Z)-1-deuterio-3,3-dimethylbut-1-enyl]benzene
• CAS: 23586-62-1
• 化学式: C₁₂H₁₆
• 分子量: 161.251
• InChiKey: DXIJHCSGLOHNES-WFKGTUHGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  (3,3-二甲基-1-丁炔)-苯 生成 (Z)-1-deuterio-3,3-dimethyl-1-phenyl-1-butene
  参考文献：
  名称：

  Organometallic compounds of Group III. XIX. Regiospecificity and stereochemistry in the hydralumination of unsymmetrical acetylenes. Controlled cis or trans reduction of 1-alkynyl derivatives

  摘要：

  DOI：

  10.1021/jo00822a012

文献信息

• Silver-catalyzed carbomagnesiation of terminal aryl and silyl alkynes and enynes in the presence of 1,2-dibromoethane
  作者：Yuuki Fujii、Jun Terao、Nobuaki Kambe

  DOI：10.1039/b820521c

  日期：——

  Regioselective carbomagnesiation of terminal alkynes and enynes with alkylGrignard reagents has been achieved by the combined use of a silver catalyst and 1,2-dibromoethane.

  通过联用银催化剂和1,2-二溴乙烷，实现了末端炔烃和烯炔与烷基格氏试剂的区域选择性羰基镁化反应。
• Silver-Catalyzed Regioselective Carbomagnesiation of Alkynes with Alkyl Halides and Grignard Reagents
  作者：Nobuaki Kambe、Yuusuke Moriwaki、Yuuki Fujii、Takanori Iwasaki、Jun Terao

  DOI：10.1021/ol2018664

  日期：2011.9.2

  A silver-catalyzed carbomagnesiation of alkynes with alkyl halides and Grignard reagents afforded alkenyl Grignard reagents regioselectively, where the alkyl group of the alkyl halide, but not that of the Grignard reagent, was introduced into the alkyne. Application to δ-haloalkylacetylenes yielded cyclopentanes or a tetrahydrofuran containing an exo-methylene substituent via 5-exo-dig cyclization

  银的炔烃与烷基卤化物和格利雅试剂的银催化碳还原反应可选择性地提供烯基格利雅试剂，其中烷基卤的烷基而不是格利雅试剂的烷基被引入炔中。到δ-haloalkylacetylenes得到应用环戊烷或含四氢呋喃外型亚甲基取代基经由5外切挖环化。
• Tellurium-zinc exchange reaction. A new preparative method of alkenylzinc reagents
  作者：Jun Terao、Nobuaki Kambe、Noboru Sonoda

  DOI：10.1016/0040-4039(96)00955-0

  日期：1996.7

  Alkenyl tellurides were converted to the corresponding alkenylzinc compounds by the reaction with diethylzinc. The exchange reaction proceeds efficiently in THF at room temperature with retention of the stereochemistry of the starting tellurides. The successive reaction of the formed alkenylzinc with 4-iodotoluene in the presence of Pd(PPh3)4 afforded a cross-coupling product as a single stereoisomer

  通过与二乙基锌反应，将烯基碲化物转化为相应的烯基锌化合物。交换反应在室温下在THF中有效进行，同时保留起始碲化物的立体化学。在Pd（PPh 3）4存在下，形成的链烯基锌与4-碘甲苯的连续反应提供了作为单一立体异构体的交叉偶联产物。
• Organometallic compounds of group III. XXII. Steric effects in the hydralumination, carbalumination, and oligomerization of tert-butyl(phenyl)acetylene
  作者：John J. Eisch、Rudolf Amtmann

  DOI：10.1021/jo00795a006

  日期：1972.11