(10-Amino-decyl)-phosphonic acid diethyl ester | 120818-69-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: (10-Amino-decyl)-phosphonic acid diethyl ester
• 英文别名: Diethyl (10-aminodecyl)phosphonate；10-diethoxyphosphoryldecan-1-amine
• CAS: 120818-69-1
• 化学式: C₁₄H₃₂NO₃P
• 分子量: 293.387
• InChiKey: IXTQQAWKUXCUGO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  19
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  61.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  氯甲酸-9-芴基甲酯 、 (10-Amino-decyl)-phosphonic acid diethyl ester 在 N-甲基咪唑 作用下， 以74%的产率得到[10-(9H-Fluoren-9-ylmethoxycarbonylamino)-decyl]-phosphonic acid diethyl ester
  参考文献：
  名称：

  Synthesis of oligodeoxyribonucleotides containing 5′-aminoalkylphosphonates

  摘要：

  DOI：

  10.1016/s0040-4039(00)80807-2
• 作为产物：
  描述：

  1,10-二溴癸烷 在 肼 作用下， 以 乙醇 、 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 41.5h， 生成 (10-Amino-decyl)-phosphonic acid diethyl ester
  参考文献：
  名称：

  磁铁矿纳米粒子表面上具有荧光染料的可逆狄尔斯-阿尔德反应

  摘要：

  纳米粒子表面上的Diels–Alder反应可对纳米级结构单元进行热可逆功能化。我们报告了通过热分解反应及其马来酰亚胺基团的功能化定义明确的磁铁矿纳米粒子的合成。通过有机膦酸酯偶联剂的合成和原始羧酸基团的部分配体交换，实现了这些亲二烯体的连接。官能化的氧化铁颗粒可通过60°C的Diels-Alder反应使糠醛官能化的若丹明B染料共价附着在表面上。产生的颗粒显示出若丹明B的典型荧光。染料可以通过逆Diels-Alder反应从颗粒表面裂解。

  DOI：

  10.3390/molecules26040877

文献信息

• KANSAL, VINOD K.;HUYNH-DINH, TAM;IGOLEN, JEAN, TETRAHEDRON LETT, 29,(1988) N 43, C. 5537-5540
  作者：KANSAL, VINOD K.、HUYNH-DINH, TAM、IGOLEN, JEAN

  DOI：——

  日期：——
• HYDROLYSABLE AND POLYMERIZABLE SILANES WITH ADJUSTABLE SPATIAL DISTRIBUTION OF THE FUNCTIONAL GROUPS, AND USE THEREOF
  申请人：Frauhofer-Gesellschaft zur Foerderung der angewardten forschung e.V.

  公开号：US20140221521A1

  公开（公告）日：2014-08-07

  The present invention relates to a process for a chain extension of radicals bonded to silicon via carbon in silanes or siloxanes while maintaining or increasing the number of functional groups on the respective Si—C-bonded radicals, wherein a silane or siloxane with a radical bonded to a silicon atom by a carbon atom, which bears at least two functional groups, wherein a first group of the functional groups is an unsaturated, organically polymerizable group and a second group of the functional groups is selected from among (a) additional unsaturated, organically polymerizable groups, (b) COOR 8 or —(O) b P(O)(R 5 ) 2 and (c) —OH, with R 8 equal to R 4 or M 1/x x+ wherein M x+ is a hydrogen or an x-fold positively charged metal cation, and b=0 or 1, is converted in a first reaction with a compound of a formula (I) X—W—(Z) a (I) wherein X is SH, NH 2 or NHR 4 , Z is OH, the carboxylic acid radical —COOH or a salt or an ester of this radical or a silyl radical, W is a substituted or non-substituted hydrocarbon, the chain of which can be interrupted by —S—, —O—, —NH—, —NR 4 —, —C(O)O—, —NHC(O)—, —C(O)NH—, —NHC(O)O—, —C(O)NHC(O)—, —NHC(O)NH—, —S(O)—, —C(S)O—, —C(S)NH—, —NHC(S)—, —NHC(S)O—, and a is 1, 2, 3, 4 or a greater whole number, wherein R 4 is a non-substituted or substituted hydrocarbon radical, R 5 is a non-substituted or substituted hydrocarbon radical or OR 6 , R 6 is hydrogen or a non-substituted or substituted hydrocarbon radical to such an extent that the radical X connects to the first functional group. Furthermore, the invention relates to multiple processes, which, based on the aforementioned first reaction, comprise additional process steps and either lead to compounds/silicic acid polycondensates with reactive groups Q, wherein Q is OH, NR 7 2 , NR 7 3 + , CO 2 H, SO 3 H, PO(OH) 2 PO(OR 4 ) 2 or a salt of the aforementioned acids, wherein R 4 has the meaning specified above for formula (I), and R 7 either has the same meaning as R 4 or two radicals R 7 together can represent a potentially substituted, potentially unsaturated alkylene group, or to compounds/silicic acid polycondensates, in which unsaturated, organically polymerizable groups are located farther out, wherein the Si—C-bonded radicals can potentially have a dendrimer-like structure. Products of the process pursuant to the invention and organic polymers produced as a result are likewise encompassed by the invention.
• US9206205B2
  申请人：——

  公开号：US9206205B2

  公开（公告）日：2015-12-08