1-bromo-4-[(Z)-dodec-3-enyl]benzene | 1233676-34-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-bromo-4-[(Z)-dodec-3-enyl]benzene
• CAS: 1233676-34-0
• 化学式: C₁₈H₂₇Br
• 分子量: 323.316
• InChiKey: WNHOMKWNLSVNNB-KTKRTIGZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.9
• 重原子数：
  19
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  1-癸炔 、 3-(4-溴苯基)丙醛 在 三(2,4,6-三甲氧基苯基)磷 、 copper dichloride 作用下， 以 二氯甲烷 、 甲苯 为溶剂， 120.0 ℃ 、101.33 kPa 条件下， 反应 24.0h， 生成 1-bromo-4-[(Z)-dodec-3-enyl]benzene 、 1-bromo-4-[(E)-dodec-3-enyl]benzene
  参考文献：
  名称：

  Ru-Catalyzed Decarbonylative Addition of Aliphatic Aldehydes to Terminal Alkynes

  摘要：

  A novel method for the formation of isolated C=C bonds was developed via a ruthenium-catalyzed decarbonylative addition of aliphatic aldehydes and alkynes. An unprecedented complete switch of chemoselectivity from aromatic aldehydes to aliphatic aldehydes was observed simply by using tri(2,4,6-trismethoxyphenyl)phosphine as ligand. A synthesis by this method of an insect sex pheromone was demonstrated.

  DOI：

  10.1021/ol101107w

文献信息

• Ru-Catalyzed Decarbonylative Addition of Aliphatic Aldehydes to Terminal Alkynes
  作者：Xiangyu Guo、Jun Wang、Chao-Jun Li

  DOI：10.1021/ol101107w

  日期：2010.7.16

  A novel method for the formation of isolated C=C bonds was developed via a ruthenium-catalyzed decarbonylative addition of aliphatic aldehydes and alkynes. An unprecedented complete switch of chemoselectivity from aromatic aldehydes to aliphatic aldehydes was observed simply by using tri(2,4,6-trismethoxyphenyl)phosphine as ligand. A synthesis by this method of an insect sex pheromone was demonstrated.