1-[2-(4-Methylphenyl)sulfanylethynyl]naphthalene | 1384843-86-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-[2-(4-Methylphenyl)sulfanylethynyl]naphthalene
• 英文别名: 1-[2-(4-methylphenyl)sulfanylethynyl]naphthalene
• CAS: 1384843-86-0
• 化学式: C₁₉H₁₄S
• 分子量: 274.386
• InChiKey: RHOVBYDBPWLPDW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1,1-二溴-2-(1-萘基)乙烯 、 4-甲苯硫酚 在 caesium carbonate 作用下， 以 二甲基亚砜 为溶剂， 以80%的产率得到1-[2-(4-Methylphenyl)sulfanylethynyl]naphthalene
  参考文献：
  名称：

  A concise synthetic strategy to alkynyl sulfides via transition-metal-free catalyzed C–S coupling of 1,1-dibromo-1-alkenes with thiophenols

  摘要：

  A novel synthetic strategy to alkynyl sulfides via transition-metal-free catalyzed C-S coupling of 1,1-dibromo-1-alkenes with thiophenols has been developed. The new strategy which avoided the transition-metal toxicities is environmental friendly and very important for alkynyl sulfides synthesis. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.05.072

文献信息

• A concise synthetic strategy to alkynyl sulfides via transition-metal-free catalyzed C–S coupling of 1,1-dibromo-1-alkenes with thiophenols
  作者：Zhangqin Ni、Sichang Wang、Hui Mao、Yuanjiang Pan

  DOI：10.1016/j.tetlet.2012.05.072

  日期：2012.7

  A novel synthetic strategy to alkynyl sulfides via transition-metal-free catalyzed C-S coupling of 1,1-dibromo-1-alkenes with thiophenols has been developed. The new strategy which avoided the transition-metal toxicities is environmental friendly and very important for alkynyl sulfides synthesis. (C) 2012 Elsevier Ltd. All rights reserved.