2-甲基-4-苯基-1,3-二氧戊环 | 33941-99-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-甲基-4-苯基-1,3-二氧戊环
• 英文名称: 2-methyl-4-phenyl-[1,3]dioxolane
• 英文别名: 2-Methyl-4-phenyl-[1,3]dioxolan；(+/-)-2-methyl-4-phenyl-1,3-dioxolane；2-methyl-4-phenyl-1,3-dioxolane；2-Methyl-4-phenyl-1.3-dioxolan
• CAS: 33941-99-0
• 化学式: C₁₀H₁₂O₂
• 分子量: 164.204
• InChiKey: YPPGSWWESBCSCT-UHFFFAOYSA-N

物化性质

• 沸点：
  242.4±25.0 °C(Predicted)
• 密度：
  1.07[at 20℃]
• LogP：
  2.19 at 24.7℃
• 保留指数：
  1226;1333

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2932999099

反应信息

• 作为反应物：
  描述：

  2-甲基-4-苯基-1,3-二氧戊环 生成 (2 S,4 R)-2-methyl-4-phenyl-1,3-dioxolane 、 (2 R,4 R)-2-methyl-4-phenyl-1,3-dioxolane
  参考文献：
  名称：

  2-METHYL-4-PHENY1-1,3-DIOXOLANE

  摘要：

  描述了化合物2-甲基-4-苯基-1,3-二氧杂环己烷的对映异构体对和纯对映体的感官特性。顺式化合物(2 S,4 R)-2-甲基-4-苯基-1,3-二氧杂环己烷和(2 S,4 R)-2-甲基-4-苯基-1,3-二氧杂环己烷在感官价值上最有价值。这些对映体和它们的混合物特别适用于用作感官活性物质，例如香料。

  公开号：

  US20070027060A1
• 作为产物：
  描述：

  苯基乙二醇 以 水 为溶剂， 生成 2-甲基-4-苯基-1,3-二氧戊环
  参考文献：
  名称：

  2-methyl-4-pheny1-1,3-dioxolane

  摘要：

  描述了化合物2-甲基-4-苯基-1,3-二氧兰的对映异构体对和纯对映体的感官特性。顺式化合物(2S,4R)-2-甲基-4-苯基-1,3-二氧兰和(2R,4S)-2-甲基-4-苯基-1,3-二氧兰是最具感官价值的。这些对映体和其混合物特别适用于用作感官活性物质，例如香料。

  公开号：

  US20010004457A1

文献信息

• MENTHYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES
  申请人：Vielhaber Gabriele

  公开号：US20130129646A1

  公开（公告）日：2013-05-23

  The present invention relates to the cosmetic, dermatological or pharmaceutical (therapeutic) use of compounds of formula (I) or a cosmetically acceptable salt of a compound of formula (I) or a mixture containing two or more of these compounds or the salts thereof wherein R 1 denotes hydrogen or an organic radical having 1 to 14 carbon atoms, R 2 denotes an organic radical having 1 to 14 carbon atoms, and wherein optionally R 1 and R 2 are covalently bonded to one another, preferably so that a 3 to 8 membered ring is formed, for the lightening of skin and/or hair. The invention further relates to compositions and cosmetic, dermatological or pharmaceutical preparations (compositions) comprising one or more compounds of formula (I) suitable for lightening human skin and/or hair and corresponding methods. The invention further relates to compounds of formula (I) as a drug, their use for the preparation of a pharmaceutical composition for lightening human skin and/or hair and to certain novel compounds of formula (I).

  本发明涉及化妆品、皮肤科或药用（治疗）用途的化合物的使用，其化学式为（I）或者化学式（I）的化妆品可接受的盐，或者含有两种或更多这些化合物或其盐的混合物，其中R1代表氢或具有1至14个碳原子的有机基，R2代表具有1至14个碳原子的有机基，可选地R1和R2彼此共价结合，最好形成3至8成员环，用于美白皮肤和/或头发。该发明还涉及包含一种或多种化学式（I）化合物的组合物和适用于美白人类皮肤和/或头发的化妆品、皮肤科或药用制剂（组合物）及相应的方法。该发明还涉及化学式（I）化合物作为药物，其用于制备用于美白人类皮肤和/或头发的药用组合物以及某些新的化学式（I）化合物。
• USE OF CERTAIN ISOPROPYL METHYLCYCLOHEXENE THIOLS AS FRAGRANCES AND/OR FLAVORS
  申请人：Ott Frank

  公开号：US20100310479A1

  公开（公告）日：2010-12-09

  A description is provided of new compounds of formula (A) and in particular the use of a compound of formula (A) or a mixture of two or more compounds of formula (A), wherein the thiol group of each compound of formula (A) independently of one another in each case is linked with the carbon atom in position 3, 4, 5 or 6, as a fragrance or flavor for imparting, modifying and/or intensifying one, two or all the smell and/or taste notes grapefruit, tropical fruits and blackcurrant Also described are fragrance and flavor compositions, preparations and methods.

  提供了一种新的化合物（A）的描述，特别是化合物（A）的使用或两种或两种以上化合物（A）的混合物的使用，其中每种化合物（A）的巯基独立地与第3、4、5或6位的碳原子连接，作为香味或风味，用于赋予、改变和/或增强葡萄柚、热带水果和黑加仑的一种、两种或所有气味和/或味道。还描述了香味和风味组合物、制剂和方法。
• Fragrance and/or flavoring compositions containing dioxolanes
  申请人：Singer Emilie

  公开号：US20120308486A1

  公开（公告）日：2012-12-06

  The present invention primarily relates to the use of dioxolanes of the following Formula (I) as fragrance and/or flavoring substances, certain perfume and/or flavoring compositions comprising these dioxolanes and corresponding perfumed and/or flavored items. The present invention also relates to a method for producing the dioxolanes of Formula (I) and certain new dioxolanes according to Formula (I).

  本发明主要涉及使用以下式（I）的二氧兰作为香料和/或调味物质，包括这些二氧兰的某些香水和/或调味物质组合物以及相应的带有香气和/或味道的物品。本发明还涉及一种制备式（I）的二氧兰和某些新的式（I）的二氧兰的方法。
• OMEGA-CYCLOHEXYLALKAN-1-OLES AND USE THEREOF AS ANTIMICROBIAL ACTIVES TO COMBAT BODY ODOR
  申请人：Kuhn Walter

  公开号：US20120107258A1

  公开（公告）日：2012-05-03

  The present invention relates to antimicrobially active ω-cyclohexylalkan-1-ales of the following formula (I), to a method for producing said compounds and to the use thereof as antimicrobial agents for treating body odor, wherein R 1 to R 6 independently of one another denote hydrogen or a linear or branched alkyl radical having 1 to 12 carbon atoms, R a and R b independently of one another denote hydrogen, a linear or branched alkyl radical having 1 to 6 carbon atoms or a linear or branched alkoxy radical having 1 to 4 carbon atoms, and x is 0 or 1, wherein preferably the total number of carbon atoms in R 1 to R 6 is 18 or less.

  本发明涉及下式（I）的抗微生物活性ω-环己基烷基-1-醇类化合物，以及制备该化合物的方法和将其用作治疗体臭的抗微生物剂。其中，R1至R6独立地表示氢或具有1至12个碳原子的线性或支链烷基基团，Ra和Rb独立地表示氢、具有1至6个碳原子的线性或支链烷基基团或具有1至4个碳原子的线性或支链烷氧基基团，x为0或1，其中优选R1至R6中碳原子的总数不超过18。
• CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS
  申请人：Meyer Imke

  公开号：US20130137710A1

  公开（公告）日：2013-05-30

  The present invention relates to the cosmetic, dermatological or therapeutic use of certain cyclohexyl carbamate compounds of formula (I) given below, preferably as anti-cellulite actives. The invention further relates to compositions and cosmetic, dermatological or therapeutic products comprising such compounds of formula (I), which are preferably suitable for the prophylaxis (prevention) and cosmetic treatment (combating) of cellulite in human beings, corresponding methods and novel compounds of formula (I) wherein A denotes wherein X, Y and Z independently of one another denote hydrogen, C1-C4-alkyl or C2-C4-alkenyl, wherein optionally two of the radicals X, Y and Z are covalently bonded to one another under formation of a bicyclic ring system, in such a bicyclic ring system two of the radicals X, Y and Z together preferably form a radical having 1 to 4 carbon atoms, preferably a hydrocarbon radical having 1 to 3 carbon atoms, B denotes NR 1 R 2 , wherein R 1 denotes hydrogen or an organic radical having 1 to 14 carbon atoms, R 2 denotes an organic radical having 1 to 14 carbon atoms, and wherein optionally R 1 and R 2 are covalently bonded to one another, preferably so that B is a 3 to 8 membered ring.

  本发明涉及以下式子（I）所示的某些环己基氨基甲酸酯化合物的化妆品、皮肤科或治疗用途，优选作为抗脂肪纹活性剂。本发明还涉及包含该式（I）化合物的组合物和化妆品、皮肤科或治疗产品，这些化合物优选用于人类的脂肪纹预防和美容治疗，以及相应的方法和新型式（I）化合物。其中，A表示......，X、Y和Z分别独立地表示氢、C1-C4烷基或C2-C4烯基，其中可选地，X、Y和Z中的两个基团彼此共价结合形成二环环系统，在这样的二环环系统中，X、Y和Z中的两个基团一起优选形成具有1至4个碳原子的基团，优选为具有1至3个碳原子的碳氢基团，B表示NR1R2，其中R1表示氢或具有1至14个碳原子的有机基团，R2表示具有1至14个碳原子的有机基团，可选地，R1和R2彼此共价结合，优选使得B为3至8个成员的环。