N-(2-Hydroxynaphthalen-1-yl)sarcosine | 58035-86-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: N-(2-Hydroxynaphthalen-1-yl)sarcosine
• 英文别名: N-(2-hydroxy-naphthalen-1-ylmethyl)-N-methyl-glycine；2-[(2-Hydroxynaphthalen-1-yl)methyl-methylamino]acetic acid
• CAS: 58035-86-2
• 化学式: C₁₄H₁₅NO₃
• mdl: MFCD21469956
• 分子量: 245.278
• InChiKey: HVHYYDPPHMWXMR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.214
• 拓扑面积：
  60.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  N-(2-Hydroxynaphthalen-1-yl)sarcosine 在 palladium on activated charcoal 盐酸 、 氢气 作用下， 以 乙二醇甲醚 、 N,N-二甲基甲酰胺 为溶剂， 生成 1-(2-amino-ethyl)-[2]naphthol
  参考文献：
  名称：

  Short,J.H.; Ours,C.W., Journal of Heterocyclic Chemistry, 1975, vol. 12, p. 869 - 876

  摘要：

  DOI：
• 作为产物：
  描述：

  聚合甲醛 、 肌氨酸 、 2-萘酚 生成 N-(2-Hydroxynaphthalen-1-yl)sarcosine
  参考文献：
  名称：

  Short,J.H.; Ours,C.W., Journal of Heterocyclic Chemistry, 1975, vol. 12, p. 869 - 876

  摘要：

  DOI：

文献信息

• Manganese(III) in a pseudo-compressed mixed-donor octahedral environment: synthesis, X-ray crystal structure and physicochemical properties
  作者：Musa S Shongwe、Sandy K Vandayar、Manuel A Fernandes、Helder M Marques、Michael J Morris、Sarah L Heath

  DOI：10.1016/s0277-5387(01)00816-6

  日期：2001.7

  The compound [C5H10NH2][MnL2] [H2L = N-(2-hydroxynaphthalen-1-yl)sarcosine] has been synthesised and characterised using single-crystal X-ray crystallography, spectroscopy and magnetic susceptibility measurements. The crystallographic asymmetric unit displays two similar, independent [MnL2](-) complex ions linked via piperidinium cations through hydrogen bonding. The complex ions are alternating and arranged in two non-interacting parallel chains. Each of the complex ions is six-co-ordinate with the donor atoms, provided by the two bifunctional tridentate sarcosinato ligands, being amine nitrogen atoms and carboxylate and naphtholate oxygen atoms. The anionic ligands are co-ordinated facially and are related by a crystallographic centre of inversion at the manganese ion. The mean bond distances Mn-O-naphtholate (1.885 Angstrom), Mn-O-carboxylate (2.069 Angstrom) and Mn-N-amine (2.198 Angstrom) for the two molecules point to a pseudo-compressed octahedral geometry about the Mn(III) ion consistent with a pseudo-Jahn-Teller compression. IR spectroscopy corroborates the unidentate co-ordination fashion of the carboxylate group of the sarcosinato ligand and confirms the presence of the piperidinium cation. The room temperature effective magnetic moment, (8 chiT)(1/2), is indicative of spin-only paramagnetism. As shown by the temperature dependence of the reciprocal of the magnetic susceptibility (chi (-1)), the magnetic behaviour of [C5H10NH2][MnL2] in the temperature range 5-300 K is in conformity with the Curie-Weiss law, chi = C/(T - theta), with theta = -0.12 K. (C) 2001 Elsevier Science Ltd. All rights reserved.
• SHORT J. H.; OURS C. W., J. HETEROCYCL. CHEM. <JHTC-AD>, 1975, 12, NO 5, 869-876
  作者：SHORT J. H.、 OURS C. W.

  DOI：——

  日期：——
• Short,J.H.; Ours,C.W., Journal of Heterocyclic Chemistry, 1975, vol. 12, p. 869 - 876
  作者：Short,J.H.、Ours,C.W.

  DOI：——

  日期：——
• Phenolic Analogs of Amino Carboxylic-Acid Ligands for Tc-99m. 3. N-(2-Hydroxybenzyl) Sarcosines (Hbs)
  作者：JG Wilson

  DOI：10.1071/ch9900783

  日期：——