N-(3-Cyanphenyl)-3-chlor-4-chlormethyl-2-pyrrolidinon | 61213-37-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: N-(3-Cyanphenyl)-3-chlor-4-chlormethyl-2-pyrrolidinon
• 英文别名: 1-m-cyanophenyl-3-chloro-4-chloromethyl-2-pyrrolidone；N-(3'-cyanophenyl)-3-chloro-4-chloromethyl-2-pyrrolidinone；3-[3-Chloro-4-(chloromethyl)-2-oxopyrrolidin-1-yl]benzonitrile
• CAS: 61213-37-4
• 化学式: C₁₂H₁₀Cl₂N₂O
• 分子量: 269.13
• InChiKey: GZNGJMFUTVATBN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  44.1
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Synergistic herbicidal compositions and method for controlling undesirable vegetation
  申请人：STAUFFER CHEMICAL COMPANY

  公开号：EP0015453A2

  公开（公告）日：1980-09-17

  Synergistic herbicidal activity is displayed by compositions comprising the following two components: (a) a pyrrolidone of the formula in which: X is selected from the group consisting of hydrogen, chlorine, and methyl; Y is selected from the group consisting of hydrogen, chlorine and bromine; Z is selected from the group consisting of chlorine and bromine; R' is selected from the group consisting of hydrogen and Ci-C4 alkyl; R2 is selected from the group consisting of hydrogen, halogen, C1-C4 alkyl, acetyl, trifluoromethyl, nitro, cyano, C1-C4 alkoxy, C1-C4 alkylthio, C1-C4 alkylsulfinyl, C1-C4 alkylsulfonyl, trifluoromethylsulfinyl, trifluoromethylsulfonyl, penta- fluoropropionamido, and 3-methylureido; and R3 is selected from the group consisting of hydrogen, C1-C4 alkyl, chlorine and trifluoromethyl; and (b) a phosphonic acid of the formula in which: R4 is selected from the group consisting of C1-C4 alkyl, C1-C4 haloalkyl, and -CH2NHCH2COOH, at a weight ratio of (a) to (b) of from about 0.1:1 to about 20:1.

  由以下两种成分组成的组合物具有协同除草活性： (a) 式中的吡咯烷酮 其中 X 选自由氢、氯和甲基组成的组； Y 选自由氢、氯和溴组成的组 Z 选自氯和溴组成的组； R' 选自由氢和 Ci-C4 烷基组成的组； R2 选自由氢、卤素、C1-C4 烷基、乙酰基、三氟甲基、硝基、氰基、C1-C4 烷氧基、C1-C4 烷硫基、C1-C4 烷基亚磺酰基、C1-C4 烷基磺酰基、三氟甲基亚磺酰基、三氟甲基磺酰基、五氟丙酰氨基和 3-甲基脲基组成的组；以及 R3 选自氢、C1-C4 烷基、氯和三氟甲基组成的组； 和 (b) 式中的膦酸 其中 R4选自由C1-C4烷基、C1-C4卤代烷基和-CH2NHCH2COOH组成的组，(a)与(b)的重量比约为0.1:1至约20:1。
• Pharmaceutical compounds and methods of use thereof
  申请人：STAUFFER CHEMICAL COMPANY

  公开号：EP0132578A1

  公开（公告）日：1985-02-13

  Novel compounds having the structural formula wherein R, and R2 are independently selected from the group consisting of hydrogen, halo, alkyl, haloalkyl, thioalkyl, thiohaloalkyl, alkoxy, cyano and nitro are provided. The compounds have various pharmacological effects, including cardiotropic, hypoglycemic, hypocholesterolemic and/or antiul- cerative effects in mammals. Methods of achieving these various pharamacological effects in mammals by administering the compounds thereto are provided. Pharmaceutical compositions and formulations including the compounds are provided along with methods of synthesis of the novel compounds.

  提供了具有结构式的新型化合物，其中 R 和 R2 分别独立地选自氢、卤素、烷基、卤代烷基、硫代烷基、硫代卤代烷基、烷氧基、氰基和硝基组成的组。 这些化合物具有各种药理作用，包括对哺乳动物的强心、降血糖、降胆固醇和/或抗氧化作用。 提供了通过给哺乳动物施用这些化合物来实现这些药理作用的方法。 提供了包括这些化合物的药物组合物和制剂，以及合成这些新型化合物的方法。
• US4110105A
  申请人：——

  公开号：US4110105A

  公开（公告）日：1978-08-29
• US4210589A
  申请人：——

  公开号：US4210589A

  公开（公告）日：1980-07-01
• US4263038A
  申请人：——

  公开号：US4263038A

  公开（公告）日：1981-04-21