4-(oxetan-3-yl)butan-1-ol | 251922-48-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧杂环丁烷
• 英文名称: 4-(oxetan-3-yl)butan-1-ol
• CAS: 251922-48-2
• 化学式: C₇H₁₄O₂
• 分子量: 130.187
• InChiKey: GRTIGISECOEBKA-UHFFFAOYSA-N

物化性质

• 沸点：
  226℃
• 密度：
  1.000
• 闪点：
  95℃

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-(oxetan-3-yl)butan-1-ol 在 palladium on activated charcoal 氢气 、 sodium hydride 作用下， 以 四氢呋喃 、 乙醇 为溶剂， 反应 0.75h， 生成 4-(oxetan-3-yl)butyl (2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoate
  参考文献：
  名称：

  Synthesis of Extremely Simplified Compounds Possessing the Key Pharmacophore Units of Taxol, Phenylisoserine and Oxetane Moieties.

  摘要：

  合成了直链化合物，这些化合物在α-和ω-位分别具有苯基异氨酸单元和氧杂环，作为紫杉醇的极简化类似物。然而，这些化合物均未表现出良好的微管抑制活性。

  DOI：

  10.1248/cpb.47.1334
• 作为产物：
  描述：

  2-(4-(benzyloxy)butyl)propane-1,3-diol 在 palladium on activated charcoal 吡啶 、 氢气 、 sodium hydride 作用下， 以 乙醇 、 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 107.0h， 生成 4-(oxetan-3-yl)butan-1-ol
  参考文献：
  名称：

  Synthesis of Extremely Simplified Compounds Possessing the Key Pharmacophore Units of Taxol, Phenylisoserine and Oxetane Moieties.

  摘要：

  合成了直链化合物，这些化合物在α-和ω-位分别具有苯基异氨酸单元和氧杂环，作为紫杉醇的极简化类似物。然而，这些化合物均未表现出良好的微管抑制活性。

  DOI：

  10.1248/cpb.47.1334

文献信息

• Loy, Rebecca N.; Jacobsen, Eric N., Journal of the American Chemical Society, 2009, vol. 131, p. 2786 - 2787
  作者：Loy, Rebecca N.、Jacobsen, Eric N.

  DOI：——

  日期：——
• IMAGE FORMING METHOD
  申请人：Konica Minolta, Inc.

  公开号：US20200215828A1

  公开（公告）日：2020-07-09

  An image forming method includes: discharging an inkjet actinic ray curable white ink containing an actinic ray polymerizable compound, a gelling agent, and titanium oxide from a nozzle of an inkjet head to attach the inkjet actinic ray curable white ink to a surface of a recording medium; irradiating the inkjet actinic ray curable white ink attached to the surface of the recording medium with an actinic ray to cure the inkjet actinic ray curable white ink; discharging an inkjet actinic ray curable ink containing an actinic ray polymerizable compound from a nozzle to attach the inkjet actinic ray curable ink to a surface of a white cured film obtained by curing the inkjet actinic ray curable white ink; and irradiating the inkjet actinic ray curable ink attached to the surface of the white cured film with an actinic ray to cure the inkjet actinic ray curable ink.
• PHOTOCURABLE RESIN COMPOSITION AND A METHOD FOR PRODUCING AN ARTICLE
  申请人：CANON KABUSHIKI KAISHA

  公开号：US20220033552A1

  公开（公告）日：2022-02-03

  A curable resin composition which provides a cured product excellent in impact resistance and flexural modulus and has a low viscosity comprising a component (A), a component (B) and a component (C). The component (A) is a compound represented by formula (1), In formula (1), R is hydrogen or a hydrocarbon group having 1 to 4 carbon atoms. The hydrocarbon group optionally has a substituent. The component (B) is a compound having one or more caprolactone modified structures and two or more radically polymerizable groups per molecule, and the component (C) is a radical polymerization initiator.
• PHOTOCURABLE RESIN COMPOSITION
  申请人：CANON KABUSHIKI KAISHA

  公开号：US20220033554A1

  公开（公告）日：2022-02-03

  A curable resin composition which provides a cured product excellent in impact resistance and flexural modulus and has a low viscosity comprising a component (A), a component (B) and a component (C). The component (A) is a compound represented by formula (1), wherein in formula (1), R is hydrogen or a hydrocarbon group having 1 to 4 carbon atoms, and the hydrocarbon group optionally has a substituent, wherein the component (B) is a compound having 3 or more to 15 or less of oxyethylene groups or oxypropylene groups and two or more radically polymerizable groups per molecule, and wherein the component (C) is a radical polymerization initiator.
• [EN] POLYCARBONATE RESIN COMPOSITION FOR OPTICAL MEMBER<br/>[FR] COMPOSITION DE RÉSINE DE POLYCARBONATE POUR ÉLÉMENT OPTIQUE<br/>[JA] 光学部材用ポリカーボネート樹脂組成物
  申请人：MITSUBISHI ENG PLASTICS CORP

  公开号：WO2020183834A1

  公开（公告）日：2020-09-17

  芳香族ポリカーボネート樹脂（Ａ）１００質量部に対し、ポリオキシテトラメチレングリコール系多元重合体（Ｂ）を０．１～３質量部、リン系安定剤（Ｃ）を０．００５～０．４質量部含有する樹脂組成物であって、　ポリオキシテトラメチレングリコール系多元重合体（Ｂ）が、ポリオキシテトラメチレングリコール系ランダム重合体成分（Ｂ１）及び（Ｂ３）を、アルキレンジオール（Ｂ２）を介して結合した構造を有する多元重合体であって、数平均分子量（Ｍｎ）が１０００～３０００であることを特徴とする光学部材用ポリカーボネート樹脂組成物。