4-Hydroxy-1-(1-propyl-cyclohexyl)-benzol | 56318-42-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-Hydroxy-1-(1-propyl-cyclohexyl)-benzol
• 英文别名: 4-(1-Propyl-cyclohexyl)-phenol；4-(1-Propylcyclohexyl)phenol
• CAS: 56318-42-4
• 化学式: C₁₅H₂₂O
• 分子量: 218.339
• InChiKey: ISGBBDVXGLIGFV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-正丙基环己醇 在 盐酸 、 三氯化铝 作用下， 生成 4-Hydroxy-1-(1-propyl-cyclohexyl)-benzol
  参考文献：
  名称：

  Dimensionality and the Dynamics of Human Unstable Equilibrium

  摘要：

  Maintaining an unstable equilibrium requires that multiple joints be coordinated so that the center of mass is kept above the base of support. The authors' aim in the present study was to discover the underlying dynamics of local (foot, hip, or head) and global (center of mass) components involved in balance control and how those dynamics are affected by changes in the available information. Participants (N = 6) had to maintain their balance on an unstable platform.. Using dimensional analyses (largest Lyapunov exponent and correlation dimension), the authors examined the active degrees of freedom involved in balance control. Results indicated a similarity in dimension between local (joints) and global (center of mass) components, between a fixed point and a limit cycle. The behavior of the center of mass was found to be more predictable than the behavior of its local constituents. In addition, the available visual information affected the predictability of the postural behavior, which suggests that vision is used in the stabilization of the low-dimensional dynamics underlying balance control.

  DOI：

  10.1080/00222890209601950

文献信息

• TRICYCLIC HETEROCYCLIC COMPOUNDS
  申请人：Dhar T.G. Murali

  公开号：US20120214767A1

  公开（公告）日：2012-08-23

  Disclosed are compounds of Formula (I) or stereoisomers or salts thereof, wherein: X 1 , X 2 , X 3 , W, Q 1 , Q 2 , and G 2 are defined herein. Also disclosed are methods of using such compounds as selective agonists for G protein-coupled receptor S1P 1 , and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.

  本发明涉及公式（I）的化合物或其立体异构体或盐，其中：X1、X2、X3、W、Q1、Q2和G2在此定义。还公开了使用这些化合物作为选择性G蛋白偶联受体S1P1的激动剂的方法，以及包含这些化合物的制药组合物。这些化合物在治疗、预防或减缓多种治疗领域的疾病或障碍方面有用，例如自身免疫性疾病和血管疾病。
• SARANKINA S. A.; KUCHKAROV A. B.; KURBANOV F. K.; RAXIMOVA B. V., IZV. VYSSH. UCHEB. ZAVEDENIJ. XIMIYA I XIM. TEXNOL. <IVUK-AR>, 1975, 18, +
  作者：SARANKINA S. A.、 KUCHKAROV A. B.、 KURBANOV F. K.、 RAXIMOVA B. V.

  DOI：——

  日期：——
• Tricyclic heterocyclic compounds
  申请人：Bristol-Myers Squibb Company

  公开号：EP2592071B1

  公开（公告）日：2019-09-18
• VERBESSERTES VERFAHREN FÜR DAS PARTIELLE EINFÄRBEN VON KUNSTSTOFFTEILEN
  申请人：Covestro Intellectual Property GmbH & Co. KG

  公开号：EP3840958A1

  公开（公告）日：2021-06-30
• US9216972B2
  申请人：——

  公开号：US9216972B2

  公开（公告）日：2015-12-22