carnosifloside III | 109985-92-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: carnosifloside III
• 英文别名: (3S,8S,9R,10R,13R,14S,17R)-4,4,9,13,14-pentamethyl-17-[(E,2R)-6-methyl-7-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhept-5-en-2-yl]-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-11-one
• CAS: 109985-92-4
• 化学式: C₄₈H₇₈O₁₈
• 分子量: 943.137
• InChiKey: UHWXBWBOPABGIG-XRSBSPCNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  66
• 可旋转键数：
  14
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  295
• 氢给体数：
  11
• 氢受体数：
  18

反应信息

• 作为反应物：
  描述：

  carnosifloside III 在 钯 氢气 作用下， 以 乙醇 为溶剂， 以75 mg的产率得到
  参考文献：
  名称：

  来自中草药Hemsleya panacis-scandens的糖苷以及与葫芦素苷的结构-味道关系。

  摘要：

  From rhizomes of Hemsleya panacis-scandens collected in Yunnan, China, eight new cucurbitane glycosides named scandenosides R1-R7 and dihydrocucurbitacin F glucoside (2-O-β-D-glucopyranoside of 23, 24-dihydrocucurbitacin F) were isolated, along with six known cucurbitane glycosides. The structures of these new glycosides were determined on the basis of chemical and spectral data except for the configuration at C-20. Of these new glycosides, scandenoside R6 tastes sweet and R5 and dihydrocucurbitacin F glucoside taste bitter, while the others are tasteless. The structure-taste relationships of cucurbitane glycosides are discussed.

  DOI：

  10.1248/cpb.36.234

文献信息

• Glycosides from Chinese medicinal plant, Hemsleya panacis-scandens, and structure-taste relationship of cucurbitane glycosides.
  作者：RYOJI KASAI、KAZUHIRO MATSUMOTO、RUI-LIN NIE、JUN ZHOU、OSAMU TANAKA

  DOI：10.1248/cpb.36.234

  日期：——

  From rhizomes of Hemsleya panacis-scandens collected in Yunnan, China, eight new cucurbitane glycosides named scandenosides R1-R7 and dihydrocucurbitacin F glucoside (2-O-β-D-glucopyranoside of 23, 24-dihydrocucurbitacin F) were isolated, along with six known cucurbitane glycosides. The structures of these new glycosides were determined on the basis of chemical and spectral data except for the configuration at C-20. Of these new glycosides, scandenoside R6 tastes sweet and R5 and dihydrocucurbitacin F glucoside taste bitter, while the others are tasteless. The structure-taste relationships of cucurbitane glycosides are discussed.