N-dodecylpropane-1,3-diamine | 63888-11-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-dodecylpropane-1,3-diamine
• 英文别名: N'-undecylpropane-1,3-diamine
• CAS: 63888-11-9
• 化学式: C₁₄H₃₂N₂
• 分子量: 228.421
• InChiKey: AZWCBSZZELLHMG-UHFFFAOYSA-N

物化性质

• 沸点：
  313.4±10.0 °C(Predicted)
• 密度：
  0.839±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  16
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  38
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-溴十一烷 、 1,3-丙二胺 在 caesium carbonate 作用下， 以 四氢呋喃 为溶剂， 反应 20.0h， 生成 N-dodecylpropane-1,3-diamine 、 N',N'-di(undecyl)propane-1,3-diamine 、 N,N'-di(undecyl)propane-1,3-diamine 、 N,N',N'-tri(undecyl)propane-1,3-diamine
  参考文献：
  名称：

  非病毒基因传递的烷基胺的组合合成和高通量筛选

  摘要：

  质粒DNA和siRNA高效传递到细胞中对于生物学和生物医学研究至关重要。尽管为开发有效的非病毒载体，例如阳离子脂质和聚合物，已经做出了巨大的努力，但是大多数载体需要多步合成，这使得这种载体的快速结构优化和组合合成变得复杂。在这里，我们提出了一种基于胺烷基化的简便，单步方法，可以快速并行合成阳离子脂质样分子（类脂质）的文库。我们利用该方法合成了200个类脂质，筛选了它们在HEK293T细胞中的转染效率。筛选后，大约有2％的新型脂质能够有效转染细胞，其效率与Lipofectamine 2000相似或更高。此外，

  DOI：

  10.1021/bc400158w

文献信息

• MODIFIED BLOCK COPOLYMER, METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER, AND RESIN COMPOSITION
  申请人：Asahi Kasei Kabushiki Kaisha

  公开号：EP3623398A1

  公开（公告）日：2020-03-18

  A modified block copolymer according to the present invention is a modified block copolymer comprising a polymer block comprising a vinyl aromatic compound as a main constituent (A), a polymer block comprising a conjugate diene compound as a main constituent (B), and an atomic group having NHx (x = 0 to 2) (C). In the modified block copolymer, the polymer block comprising a conjugate diene compound as a main constituent (B) is a hydrogenated product, the atomic group having NHx (x = 0 to 2) (C) is contained in a side chain, and a compound forming the atomic group having NHx (x = 0 to 2) (C) satisfies the following condition: Condition: when the compound forming the atomic group having NHx (x = 0 to 2) (C) is reacted with a maleic anhydride-modified group in a maleic anhydride-modified block copolymer, a MFR value at 230°C under a load of 2.16 kg of the modified block copolymer after the reaction is 0.1 times or more a MFR value at 230°C under a load of 2.16 kg of the maleic anhydride-modified block copolymer before the reaction.

  根据本发明，改性嵌段共聚物是一种改性嵌段共聚物，包括以乙烯基芳香族化合物为主要成分的聚合物嵌段（A）、以共轭二烯化合物为主要成分的聚合物嵌段（B）和具有 NHx（x = 0 至 2）的原子团（C）。在改性嵌段聚合物中，由共轭二烯化合物作为主要成分（B）的聚合物嵌段是氢化产物，具有 NHx（x = 0 至 2）（C）的原子团包含在侧链中，形成具有 NHx（x = 0 至 2）（C）的原子团的化合物满足以下条件： 条件：当形成具有 NHx（x = 0 至 2）(C)的原子团的化合物与马来酸酐改性嵌段共聚物中的马来酸酐改性基团反应时，反应后在 230℃、负载 2.16 千克改性嵌段共聚物时的 MFR 值是反应前在 230℃、负载 2.16 千克马来酸酐改性嵌段共聚物时的 MFR 值的 0.1 倍或以上。
• Modified block copolymer, method for producing modified block copolymer, and resin composition
  申请人：Asahi Kasei Kabushiki Kaisha

  公开号：US11124593B2

  公开（公告）日：2021-09-21

  A modified block copolymer according to the present invention is a modified block copolymer comprising a polymer block comprising a vinyl aromatic compound as a main constituent (A), a polymer block comprising a conjugate diene compound as a main constituent (B), and an atomic group having NHx (x=0 to 2) (C). In the modified block copolymer, the polymer block comprising a conjugate diene compound as a main constituent (B) is a hydrogenated product, the atomic group having NHx (x=0 to 2) (C) is contained in a side chain, and a compound forming the atomic group having NHx (x=0 to 2) (C).

  根据本发明，改性嵌段共聚物是一种改性嵌段共聚物，包括以乙烯基芳香族化合物为主要成分的聚合物嵌段（A）、以共轭二烯化合物为主要成分的聚合物嵌段（B）和具有 NHx（x=0 至 2）的原子团（C）。在改性嵌段共聚物中，由共轭二烯化合物作为主要成分（B）的聚合物嵌段是氢化产物，具有 NHx（x=0 至 2）（C）的原子团包含在侧链中，以及形成具有 NHx（x=0 至 2）（C）的原子团的化合物。
• LUBRICATING OIL COMPOSITION
  申请人：Showa Shell Sekiyu K. K.

  公开号：EP2074202A2

  公开（公告）日：2009-07-01
• Lubricating Oil Composition
  申请人：Kaneko Hiroshi

  公开号：US20090318320A1

  公开（公告）日：2009-12-24

  The present invention involves the addition of an aspartic acid derivative and a fatty acid ester of a polyhydric alcohol to a base oil of, e.g., mineral oil or synthetic oil type. By including these additives, a lubricating oil composition having excellent rust-preventing properties, reduced friction coefficient and excellent energy-saving properties and so being suitable for industrial lubricating oils can be obtained. Also, by further adding an epoxy compound and by adding also a fatty acid amine, it is possible to obtain a lubricating oil composition even more endowed with rust-preventing properties and energy-saving properties.
• Modified Block Copolymer, Method for Producing Modified Block Copolymer, and Resin Composition
  申请人：Asahi Kasei Kabushiki Kaisha

  公开号：US20200199282A1

  公开（公告）日：2020-06-25

  A modified block copolymer according to the present invention is a modified block copolymer comprising a polymer block comprising a vinyl aromatic compound as a main constituent (A), a polymer block comprising a conjugate diene compound as a main constituent (B), and an atomic group having NHx (x=0 to 2) (C). In the modified block copolymer, the polymer block comprising a conjugate diene compound as a main constituent (B) is a hydrogenated product, the atomic group having NHx (x=0 to 2) (C) is contained in a side chain, and a compound forming the atomic group having NHx (x=0 to 2) (C).