trans-methyl-2-(hex-1-en-1-yl)benzoate | 1311408-35-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: trans-methyl-2-(hex-1-en-1-yl)benzoate
• 英文别名: 2-{(1E)-hexenyl}methylbenzoate；methyl 2-[(E)-hex-1-enyl]benzoate
• CAS: 1311408-35-1
• 化学式: C₁₄H₁₈O₂
• 分子量: 218.296
• InChiKey: RFNVYBUOWYBDEL-RMKNXTFCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  反式-1-己烯-1-基硼酸 在 potassium phosphate monohydrate 、 palladium diacetate 、 三环己基膦 作用下， 以 1,4-二氧六环 、 甲苯 为溶剂， 反应 1.33h， 生成 trans-methyl-2-(hex-1-en-1-yl)benzoate
  参考文献：
  名称：

  Microwave-assisted Suzuki–Miyaura cross-coupling of 2-alkyl and 2-alkenyl-benzo-1,3,2-diazaborolanes

  摘要：

  Nitrogen-based boronate esters, such as 2-octyl-benzo-1,3,2-diazaborolane, 2-phenethyl-benzo-1,3,2-diazaborolane, and 2-{(1E)-hexenyl}-benzo-1,3,2-diazaborolane have been shown to be suitable coupling partners with arylhalides in microwave accelerated Suzuki cross-coupling reactions. Reaction yields of up to 89% were achieved. The use of a silicon group attached to the nitrogen atom, proved to enhance the reactivity of 2-octyl-benzo-1,3,2-diazaborolane. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.03.095

文献信息

• Ligand-free nickel-catalyzed semihydrogenation of alkynes with sodium borohydride: a highly efficient and selective process for cis-alkenes under ambient conditions
  作者：Xin Wen、Xiaozhen Shi、Xianliang Qiao、Zhilei Wu、Guoyi Bai

  DOI：10.1039/c7cc02140b

  日期：——

  Highly efficient and selective semihydrogenation of alkynes has been achieved using ligand-free Ni nanoparticles and sodium borohydride under ambient conditions.

  已经在常温下使用无配体的镍纳米颗粒和硼氢化钠实现了炔烃的高效选择性半氢化。
• SPIROIMIDAZOLONE DERIVATIVE
  申请人：Esaki Toru

  公开号：US20120270838A1

  公开（公告）日：2012-10-25

  The present invention relates to a compound represented by the following formula (1): wherein W, X, Y, R 1 , R 2 , R 33 , R 34 , m and n are as defined in the claims, or a pharmacologically acceptable salt thereof.

  本发明涉及下式（1）所表示的化合物：其中W、X、Y、R1、R2、R33、R34、m和n如权利要求所定义，或其药学上可接受的盐。
• US9169254B2
  申请人：——

  公开号：US9169254B2

  公开（公告）日：2015-10-27
• US9487517B2
  申请人：——

  公开号：US9487517B2

  公开（公告）日：2016-11-08
• Microwave-assisted Suzuki–Miyaura cross-coupling of 2-alkyl and 2-alkenyl-benzo-1,3,2-diazaborolanes
  作者：Siphamandla W. Hadebe、Siphamandla Sithebe、Ross S. Robinson

  DOI：10.1016/j.tet.2011.03.095

  日期：2011.6

  Nitrogen-based boronate esters, such as 2-octyl-benzo-1,3,2-diazaborolane, 2-phenethyl-benzo-1,3,2-diazaborolane, and 2-(1E)-hexenyl}-benzo-1,3,2-diazaborolane have been shown to be suitable coupling partners with arylhalides in microwave accelerated Suzuki cross-coupling reactions. Reaction yields of up to 89% were achieved. The use of a silicon group attached to the nitrogen atom, proved to enhance the reactivity of 2-octyl-benzo-1,3,2-diazaborolane. (C) 2011 Elsevier Ltd. All rights reserved.