1-(4-acetoxy-3-methoxyphenyl)allyl 2-(4-chlorophenyl)-3-methylbutanoate | 1346660-53-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: 1-(4-acetoxy-3-methoxyphenyl)allyl 2-(4-chlorophenyl)-3-methylbutanoate
• 英文别名: 1-(4-Acetyloxy-3-methoxyphenyl)prop-2-enyl 2-(4-chlorophenyl)-3-methylbutanoate；1-(4-acetyloxy-3-methoxyphenyl)prop-2-enyl 2-(4-chlorophenyl)-3-methylbutanoate
• CAS: 1346660-53-4
• 化学式: C₂₃H₂₅ClO₅
• 分子量: 416.901
• InChiKey: WIAFRILQGXQLJC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  29
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  61.8
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  乙酸丁香酚酯 在 N-溴代丁二酰亚胺(NBS) 、 sodium hydroxide 作用下， 以 四氯化碳 、 水 为溶剂， 反应 43.0h， 生成 1-(4-acetoxy-3-methoxyphenyl)allyl 2-(4-chlorophenyl)-3-methylbutanoate
  参考文献：
  名称：

  Design and synthesis of novel pyrethriods containing eugenol moiety

  摘要：

  A novel series of pyrethriods was designed and synthesized by connecting various eugenol derivatives to either a chrysanthematic acid or 2-(4-chlorophenyl)-3-methylbutanoic acid. The insecticidal activity of target compounds has been evaluated by an immersion method on the fourth instar larvae of Culex pipens quinquefasciatus. The results revealed that the larvae were sensitive to synthesized compounds. Varying substituents in both acid moiety and eugenol group resulted in new compounds that exhibited different contact toxicity. Compound 3a showed the highest activity and is currently under further investigation.

  DOI：

  10.1007/s00044-011-9809-8

文献信息

• Design and synthesis of novel pyrethriods containing eugenol moiety
  作者：Xinlong Wang、Meigui Yi、Quanhai Du、Aimin Wu、Rong Xiao

  DOI：10.1007/s00044-011-9809-8

  日期：2012.10

  A novel series of pyrethriods was designed and synthesized by connecting various eugenol derivatives to either a chrysanthematic acid or 2-(4-chlorophenyl)-3-methylbutanoic acid. The insecticidal activity of target compounds has been evaluated by an immersion method on the fourth instar larvae of Culex pipens quinquefasciatus. The results revealed that the larvae were sensitive to synthesized compounds. Varying substituents in both acid moiety and eugenol group resulted in new compounds that exhibited different contact toxicity. Compound 3a showed the highest activity and is currently under further investigation.