4,5-Dichloro-3,6-bis-trimethylsilanyloxy-phthalonitrile | 150699-80-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4,5-Dichloro-3,6-bis-trimethylsilanyloxy-phthalonitrile
• 英文别名: 4,5-Dichloro-3,6-bis(trimethylsilyloxy)benzene-1,2-dicarbonitrile
• CAS: 150699-80-2
• 化学式: C₁₄H₁₈Cl₂N₂O₂Si₂
• 分子量: 373.386
• InChiKey: LYRVMOQDCMLLHF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.16
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  66
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  trimethylsilyl (1S,3aS,3bS,5aR,9aR,9bS,11aS)-8-(4,5-dichloro-1,2-dicyano-3-hydroxy-6-oxocyclohexa-2,4-dien-1-yl)-9a,11a-dimethyl-7-trimethylsilyloxy-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinoline-1-carboxylate 生成 4,5-Dichloro-3,6-bis-trimethylsilanyloxy-phthalonitrile
  参考文献：
  名称：

  BHATTACHARYA, APURBA;DIMICHELE, LISA M.;DOLLING, ULF-H.;DOUGLAS, ALAN W.;+, J. AMER. CHEM. SOC., 110,(1988) N 10, 3318-3319

  摘要：

  DOI：

文献信息

• Highly Efficient and Chemoselective Reductive Bis-silylation of Quinones by Silyltellurides
  作者：Shigeru Yamago、Hiroshi Miyazoe、Kazunori Iida、Jun-ichi Yoshida

  DOI：10.1021/ol006581e

  日期：2000.11.1

  [GRAPHICS]Silyltellurides serve as new silicon-based chemoselective reducing agents and reduce quinones to the corresponding bis-silylated hydroquinones. The reaction proceeds under ambient thermal conditions without the need of any additional promoters or catalysts and gives the products in excellent yields. Several control experiments suggest that the reaction is initiated by a single electron transfer from silyltellurides to quinones.
• BHATTACHARYA, APURBA;DIMICHELE, LISA M.;DOLLING, ULF-H.;DOUGLAS, ALAN W.;+, J. AMER. CHEM. SOC., 110,(1988) N 10, 3318-3319
  作者：BHATTACHARYA, APURBA、DIMICHELE, LISA M.、DOLLING, ULF-H.、DOUGLAS, ALAN W.、+

  DOI：——

  日期：——