4-Amidinobenzylmethylketon | 60925-51-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-Amidinobenzylmethylketon
• 英文别名: Benzenecarboximidamide, 4-(2-oxopropyl)-；4-(2-oxopropyl)benzenecarboximidamide
• CAS: 60925-51-1
• 化学式: C₁₀H₁₂N₂O
• 分子量: 176.218
• InChiKey: KQDVOAFSTVCSKP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  66.9
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  4-(2-Oxo-propyl)-benzimidic acid methyl ester; hydrochloride 在 氨 作用下， 以 乙醇 为溶剂， 生成 4-Amidinobenzylmethylketon
  参考文献：
  名称：

  Wagner; Voigt, Pharmazie, 1976, vol. 31, # 7, p. 432 - 436

  摘要：

  DOI：

文献信息

• IMMUNOMODULATING POLYNUCLEOTIDES, ANTIBODY CONJUGATES THEREOF, AND METHODS OF THEIR USE
  申请人：TOLLNINE, INC.

  公开号：US20220056069A1

  公开（公告）日：2022-02-24

  Immunomodulating polynucleotides are disclosed. The immunomodulating polynucleotides may contain 5-modified uridine, 5-modified cytidine, a total of from 6 to 16 nucleotides, and/or one or more abasic spacers and/or internucleoside phosphotriesters. Also disclosed are conjugates containing a targeting moiety and one or more immunomodulating polynucleotides. The immunomodulating polynucleotides and conjugates may further contain one or more auxiliary moieties. Also disclosed are compositions containing the immunomodulating polynucleotides or the conjugates containing one or more stereochemically enriched internucleoside phosphorothioates. Further disclosed are pharmaceutical compositions containing the immunomodulating polynucleotides or the conjugates and methods of their use.
• Wagner; Voigt, Pharmazie, 1976, vol. 31, # 7, p. 432 - 436
  作者：Wagner、Voigt

  DOI：——

  日期：——