2-羟基-芴-1-羧酸 | 106782-30-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 中文名称: 2-羟基-芴-1-羧酸
• 英文名称: 2-hydroxy-fluorene-1-carboxylic acid
• 英文别名: 2-Hydroxy-fluoren-1-carbonsaeure；2-Hydroxy-fluorene carboxylic acid；2-hydroxy-9H-fluorene-1-carboxylic acid
• CAS: 106782-30-3
• 化学式: C₁₄H₁₀O₃
• 分子量: 226.232
• InChiKey: HKWWJLRNLWQLID-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-羟基-芴-1-羧酸 生成 2-hydroxy-fluorene-1-carboxylic acid o-toluidide
  参考文献：
  名称：

  DE530293

  摘要：

  公开号：
• 作为产物：
  描述：

  2-羟基芴 、 methylammonium carbonate 在 sodium carbonate 作用下， 生成 2-羟基-芴-3-羧酸 、 2-羟基-芴-1-羧酸
  参考文献：
  名称：

  Ortho-hydroxy-carboxylic acids of fluorene

  摘要：

  公开号：

  US01867049A1

文献信息

• FUNCTIONAL BIODEGRADABLE POLYMERS
  申请人：Pugh Coleen

  公开号：US20130184429A1

  公开（公告）日：2013-07-18

  Biodegradable polyesters are made by synthesizing copolymers derived from biodegradable hydroxyacid monomers as well as from hydroxyacid monomers containing a functional group such as an azide group, a halogen group, a thioacetate group, and the like. Preferably, the functionalized biodegradable polyester copolymers are derived from a functionalized hydroxyacid such as a homolog of lactic acid and/or glycolic acid with the copolyester thus containing functional groups on the backbone thereof. These biodegradable polyesters can be utilized wherever biodegradable polyesters are currently used, and also serve as a polymer to which various medical and drug delivery systems can be attached.

  可生物降解聚酯是通过合成来自可生物降解羟基酸单体和含有官能团的羟基酸单体的共聚物制成的，例如偶氮基团、卤素基团、硫代乙酸酯基团等。最好使用含有官能团的可生物降解聚酯共聚物来自含有官能团的羟基酸，例如乳酸和/或甘醇酸的同系物，因此共聚酯具有官能团。这些可生物降解聚酯可以用于目前使用可生物降解聚酯的任何地方，并且还可以作为可以连接各种医疗和药物输送系统的聚合物。
• Functional biodegradable polymers
  申请人：Pugh Coleen

  公开号：US10023689B2

  公开（公告）日：2018-07-17

  Biodegradable polyesters are made by synthesizing copolymers derived from biodegradable hydroxyacid monomers as well as from hydroxyacid monomers containing a functional group such as an azide group, a halogen group, a thioacetate group, and the like. Preferably, the functionalized biodegradable polyester copolymers are derived from a functionalized hydroxyacid such as a homolog of lactic acid and/or glycolic acid with the copolyester thus containing functional groups on the backbone thereof. These biodegradable polyesters can be utilized wherever biodegradable polyesters are currently used, and also serve as a polymer to which various medical and drug delivery systems can be attached.

  可生物降解的聚酯是由可生物降解的羟基酸单体以及含有叠氮基、卤素基、硫代乙酸基等官能团的羟基酸单体合成共聚物制成的。官能化的可生物降解聚酯共聚物最好来自官能化的羟基酸，如乳酸和/或乙醇酸的同系物，因此共聚物的骨架上含有官能团。这些可生物降解的聚酯可用于目前使用可生物降解的聚酯的任何地方，也可作为聚合物附着在各种医疗和药物输送系统上。
• Synthesis of hydroxyfluorene-carboxilic acid and esters thereof
  申请人：Mandava Naga Bhushan

  公开号：US10351504B1

  公开（公告）日：2019-07-16

  Methods of synthesizing phenanthrenequinone, 9-hydroxyfluorene-9-5 carboxylic acid (“HFCA”), methyl-9-hydroxyfluorene-carboxylate (“HFCA methyl ester”) and methyl-2-chloro-9-hydroxyfluorenecarboxylate, (“Chlorflurenol”) starting from preferred embodiment are disclosed. Several reaction products of phenanthrene are useful in industry, and are valuable plant growth regulators.

  公开了从优选实施例开始合成菲醌、9-羟基芴-9-5 羧酸（"HFCA"）、9-羟基芴-羧酸甲酯（"HFCA 甲酯"）和 2-氯-9-羟基芴羧酸甲酯（"氯芴醇"）的方法。菲的几种反应产物在工业中非常有用，是有价值的植物生长调节剂。
• Ishikawa, Nippon Kagaku Zasshi, 1959, vol. 80, p. 1358
  作者：Ishikawa

  DOI：——

  日期：——
• SOLID PHASE LIPOGLYCOPEPTIDE LIBRARY, COMPOSITIONS AND METHODS
  申请人：Intercardia, Inc.

  公开号：EP0934076A1

  公开（公告）日：1999-08-11