2,6-Dichlorobenzenesulfonyl isocyanate | 71103-41-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,6-Dichlorobenzenesulfonyl isocyanate
• 英文别名: 2,6-dichloro-N-(oxomethylidene)benzenesulfonamide
• CAS: 71103-41-8
• 化学式: C₇H₃Cl₂NO₃S
• 分子量: 252.07
• InChiKey: RHPCYVNTFRAYEO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  72
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-methoxy-N,6-dimethylpyrimidin-2-amine 、 2,6-Dichlorobenzenesulfonyl isocyanate 生成 N-[N-(4-methoxy-6-methylpyrimidine-2-yl)-N-methylaminocarbonyl]-2,6-dichlorobenzenesulfonamide
  参考文献：
  名称：

  LEVITT, G.

  摘要：

  DOI：

文献信息

• 1-carbonyl-2-pyrazoline derivatives having herbicidal activity
  申请人：Duphar International Research B.V.

  公开号：US04927452A1

  公开（公告）日：1990-05-22

  The invention relates to a herbicidally active compound of the general ##STR1## wherein R.sub.1, R.sub.2 R.sub.3 and R.sub.4 are equal or different and represent hydrogen atoms, alkyl groups having 1-6 carbon atoms, cycloalkyl groups having 3-6 carbon atoms or alkoxycarbonyl groups having 2-5 carbon atoms; R.sub.5 is a hydrogen atom, an alkyl group or haloalkyl group having 1-8 carbon atoms, a substituted or non-substituted phenyl group, a substituted or non-substituted heterocyclic group, or an alkenyl, alkynyl or alkoxycarbonyl group having 2-5 carbon atoms; and wherein two of the groups R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 together may form a straight or branched alkylene group having 3-5 carbon atoms; Ar is a phenyl group, a phenyl (C.sub.1 -C.sub.4)alkyl group or a heteroaryl group; R.sub.6 is a hydrogen atom or substitutent to Ar, which substituent, in case Ar is a phenyl or phenylalkyl group, is attached to the phenyl group in the ortho position with respect to the sulphonyl or sulphonylalkyl group, and which substituent is selected from the following atoms and groups: a halogen atom; a nitro group; an alkoxycarbonyl group that has 2-8 carbon atoms and is unsubstituted or substituted with one or more hydroxy or C.sub.1 -C.sub.4 alkoxy groups; and an alkyl, hydroxyalkyl, haloalkyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, alkylsulphonyl and haloalkylsulphonyl group having 1-6 carbon atoms; and R.sub.7 represent a hydrogen atom or one or two halogen atoms or C.sub.1 -C.sub.4 alkyl groups.

  本发明涉及一种具有除草活性的化合物，其一般式为##STR1##其中R.sub.1、R.sub.2、R.sub.3和R.sub.4相等或不同，表示氢原子、具有1-6个碳原子的烷基、具有3-6个碳原子的环烷基或具有2-5个碳原子的烷氧羰基基团；R.sub.5表示氢原子、具有1-8个碳原子的烷基或卤代烷基、取代或未取代的苯基、取代或未取代的杂环基或具有2-5个碳原子的烯基、炔基或烷氧羰基基团；其中R.sub.1、R.sub.2、R.sub.3、R.sub.4和R.sub.5中的两个基团可以共同形成一个直链或分支链的3-5个碳原子的烷基基团；Ar表示苯基、苯基（C.sub.1-C.sub.4）烷基基团或杂环基；R.sub.6表示与Ar相连的氢原子或取代基，该取代基在Ar为苯基或苯基烷基基团时，与磺酰基或磺酰基烷基基团相对应的苯基在邻位上连接，所述取代基选自以下原子和基团：卤原子；硝基基团；具有2-8个碳原子且未取代或取代有一个或多个羟基或C.sub.1-C.sub.4烷氧基团的烷氧羰基基团；以及具有1-6个碳原子的烷基、羟基烷基、卤代烷基、烷氧基、卤代烷氧基、烷硫基、卤代烷硫基、烷基磺酰基和卤代烷基磺酰基基团；R.sub.7表示氢原子或1-2个卤原子或C.sub.1-C.sub.4烷基基团。
• Herbicidal sulfonamides
  申请人：E. I. Du Pont de Nemours and Company

  公开号：US04443244A1

  公开（公告）日：1984-04-17

  N-(heterocyclicaminocarbonyl)arylsulfonamides in which at least one of the acyclic nitrogens thereof is substituted by lower alkyl, or sometimes in the case of aminocarbonyl nitrogen, by methoxy; e.g. N-[N-(4,6-dimethoxy-1,3,5-triazin-2-yl)-N-methylaminocarbonyl]-2-chloroben zenesulfonamide or N-[N-(4,6-dimethoxy-1,3,5-triazin-2-yl)-N-methylaminocarbonyl]-2-nitrobenz enesulfonamide; are useful for the regulation of plant growth and as general and selective herbicides.

  N-(杂环氨基甲酰基)芳基磺酰胺，其中至少有一个非环状氮原子被较低的烷基取代，或者有时在氨基甲酰基氮原子的情况下被甲氧基取代；例如N-[N-(4,6-二甲氧基-1,3,5-三嗪-2-基)-N-甲基氨基甲酰基]-2-氯苯磺酰胺或N-[N-(4,6-二甲氧基-1,3,5-三嗪-2-基)-N-甲基氨基甲酰基]-2-硝基苯磺酰胺；对于植物生长的调节以及作为一般和选择性除草剂具有用途。
• Quinazoline derivatives and applications thereof
  申请人：Suntory Limited

  公开号：US05814631A1

  公开（公告）日：1998-09-29

  A chymase inhibitor containing as its effective ingredient a quinazoline derivative, or a pharmaceutically acceptable salt thereof, having the formula (1): ##STR1## and a pharmaceutical preparation for the prevention of cardiac and circulatory system diseases derived from abnormal exacerbation of Ang II production containing the same as its effective ingredient.

  一种含有喹唑啉衍生物或其药学上可接受的盐作为有效成分的chymase抑制剂，其化学式为（1）： ##STR1## 以及一种以该化合物作为有效成分的预防心脏和循环系统疾病的制药制剂，该疾病是由于Ang II产生异常恶化引起的。
• QUINAZOLINE DERIVATIVES AND USE THEREOF
  申请人：SUNTORY LIMITED

  公开号：EP0795548A1

  公开（公告）日：1997-09-17

  A chymase inhibitor containing as its effective ingredient a quinazoline derivative, or a pharmaceutically acceptable salt thereof, having the formula (1): and a pharmaceutical preparation for the prevention of cardiac and circulatory system diseases derived from abnormal exacerbation of Ang II production containing the same as its effective ingredient.

  一种糜蛋白酶抑制剂，其有效成分含有式（1）的喹唑啉衍生物或其药学上可接受的盐： 以及一种用于预防因血管紧张素 II 生成异常增加而引起的心脏和循环系统疾病的药物制剂，其有效成分也包含上述成分。
• LEVITT, G.
  作者：LEVITT, G.

  DOI：——

  日期：——