2-羟基苯(甲)醛聚合甲醛和甲基苯酚 | 756501-89-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-羟基苯(甲)醛聚合甲醛和甲基苯酚
• 中文别名: (3-异丙基苯基)甲硫醇
• 英文名称: [3-(Propan-2-yl)phenyl]methanethiol
• 英文别名: (3-propan-2-ylphenyl)methanethiol
• CAS: 756501-89-0
• 化学式: C₁₀H₁₄S
• 分子量: 166.29
• InChiKey: DIXFXJKBUMMICN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• TETRAPHENYLPORPHYRIN DERIVATIVE
  申请人：KYOTO UNIVERSITY

  公开号：US20200087315A1

  公开（公告）日：2020-03-19

  Provided is a ligand capable of stably bonding together interfaces composed of different types of nanoparticles, different bulk interfaces, or an interface composed of nanoparticles and a bulk interface. A tetraphenylporphyrin derivative represented by the following formula (I): wherein in formula (I), R 1 , R 2 , R 3 , and R 4 are each independently one substituent selected from the group consisting of the following formulas (II) to (VII); and X and Y are any substituents that are different from each other:

  提供了一种配体，能够稳定地结合不同类型纳米颗粒组成的界面、不同的大块界面，或由纳米颗粒和大块界面组成的界面。以下是由下式（I）表示的四苯基卟啉衍生物： 在式（I）中，R1、R2、R3和R4分别独立地是选自以下式（II）到（VII）的基团之一；X和Y是彼此不同的任意基团。
• Sulfonic acids, their derivatives and pharmaceutical compositions containing them
  申请人：Dompé S.P.A.

  公开号：EP1457485A1

  公开（公告）日：2004-09-15

  Selected sulfonic acids, their derivatives and pharmaceutical compositions containing such compounds are useful in inhibiting the chemotactic activation of neutrophils (PMN leukocytes) induced by the interaction of Interleukin-8 (IL-8) with CXCR1 and CXCR2 membrane receptors. The compounds are used for the prevention and treatment of pathologies deriving from said activation. Notably, the selected sulfonic acids and their derivativas are devoid of cyclo-oxygenase inhibition activity and are particularly useful in the treatment of neutrofil-dependent pathologies such as psoriasis, ulcerative colitis, melanoma, chronic obstructive pulmonary disease (COPD), bullous pemphigoid, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis and in the prevention and treatment of damages caused by ischemia and reperfusion.

  选择性磺酸、它们的衍生物和含有这些化合物的药物组合物在抑制由白细胞介素-8（IL-8）与CXCR1和CXCR2膜受体相互作用引起的中性粒细胞（PMN白细胞）趋化活化方面是有用的。这些化合物用于预防和治疗由该活化引起的病理状况。值得注意的是，所选的磺酸及其衍生物不具有环氧化酶抑制活性，特别适用于治疗中性粒细胞依赖性病理状况，如银屑病、溃疡性结肠炎、黑色素瘤、慢性阻塞性肺疾病（COPD）、大疱性类天疱疮、类风湿性关节炎、特发性纤维化、肾小球肾炎以及预防和治疗缺血再灌注引起的损伤。
• Tetraphenylporphyrin derivative
  申请人：KYOTO UNIVERSITY

  公开号：US11008330B2

  公开（公告）日：2021-05-18

  Provided is a ligand capable of stably bonding together interfaces composed of different types of nanoparticles, different bulk interfaces, or an interface composed of nanoparticles and a bulk interface. A tetraphenylporphyrin derivative represented by the following formula (I): wherein in formula (I), R1, R2, R3, and R4 are each independently one substituent selected from the group consisting of the following formulas (II) to (VII); and X and Y are any substituents that are different from each other:

  本发明提供了一种配体，该配体能够将不同类型的纳米颗粒组成的界面、不同的块状界面或由纳米颗粒和块状界面组成的界面稳定地结合在一起。由下式（I）代表的四苯基卟啉衍生物： 其中，在式 (I) 中，R1、R2、R3 和 R4 各自独立地为一个从下式 (II) 至 (VII) 所组成的组中选出的取代基；以及 X 和 Y 为彼此不同的任何取代基：
• SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
  申请人：Dompé S.P.A.

  公开号：EP1606248A2

  公开（公告）日：2005-12-21
• Modulation of Bacterial Quorum Sensing with Synthetic Ligands
  申请人：Blackwell Helen E.

  公开号：US20080312319A1

  公开（公告）日：2008-12-18

  The present invention provides compounds and methods for modulation of the quorum sensing of bacteria. In an embodiment, the compounds of the present invention are able to act as replacements for naturally occurring bacterial quorum sensing ligands in a ligand-protein binding system; that is, they imitate the effect of natural ligands and produce an agonistic effect. In another embodiment, the compounds of the present invention are able to act in a manner which disturbs or inhibits the naturally occurring ligand-protein binding system in quorum sensing bacteria; that is, they produce an antagonistic effect. The compounds of the present invention comprise N-acylated-homoserine lactones (AHLs) comprised of a wide range of acyl groups.