benzo-1-aza-3,7-dioxabicyclo<4.3.0>nonane | 128228-20-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶嗪类
• 英文名称: benzo-1-aza-3,7-dioxabicyclo<4.3.0>nonane
• 英文别名: 2,3,5,10b-tetrahydrooxazolo[3,2-c][1,3]benzoxazine；2,3,5,10b-tetrahydro-[1,3]oxazolo[3,2-c][1,3]benzoxazine
• CAS: 128228-20-6
• 化学式: C₁₀H₁₁NO₂
• 分子量: 177.203
• InChiKey: AQKPUYNSJFDXRI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  21.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  聚合甲醛 、 2-羟基-N-(O-羟基苄亚基)乙基胺 以 苯 为溶剂， 以90.7 g的产率得到benzo-1-aza-3,7-dioxabicyclo<4.3.0>nonane
  参考文献：
  名称：

  Synthesis and Corrosion-Protective Properties of 2,3,5,10b-Tetrahydrooxazolo[3,2-c][1,3]benzoxazine

  摘要：

  A new method was developed for one-pot synthesis of 2,3,5,10b-tetrahydrooxazolo[3,2-c][1,3]benzoxazine in 51% yield by successive reactions of monoethanolamine with salicylaldehyde and paraformaldehyde. The corrosion-protective properties of the title compound and intermediate N-(2-hydroxybenzylidene)2-aminoethanol were studied.

  DOI：

  10.1023/b:rjac.0000038830.44234.79

文献信息

• Kukharev, B. F., Journal of Organic Chemistry USSR (English Translation), 1989, vol. 25, # 11.2, p. 2211
  作者：Kukharev, B. F.

  DOI：——

  日期：——
• Synthesis and Corrosion-Protective Properties of 2,3,5,10b-Tetrahydrooxazolo[3,2-c][1,3]benzoxazine
  作者：B. F. Kukharev、V. K. Stankevich、G. R. Klimenko、V. A. Kukhareva、E. N. Kovalyuk、V. V. Bayandin

  DOI：10.1023/b:rjac.0000038830.44234.79

  日期：2004.5

  A new method was developed for one-pot synthesis of 2,3,5,10b-tetrahydrooxazolo[3,2-c][1,3]benzoxazine in 51% yield by successive reactions of monoethanolamine with salicylaldehyde and paraformaldehyde. The corrosion-protective properties of the title compound and intermediate N-(2-hydroxybenzylidene)2-aminoethanol were studied.