Tert-butyl-[1-[2-[2-[dimethyl(phenyl)silyl]ethynyl]phenyl]ethenoxy]-dimethylsilane | 371964-05-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Tert-butyl-[1-[2-[2-[dimethyl(phenyl)silyl]ethynyl]phenyl]ethenoxy]-dimethylsilane
• 英文别名: tert-butyl-[1-[2-[2-[dimethyl(phenyl)silyl]ethynyl]phenyl]ethenoxy]-dimethylsilane
• CAS: 371964-05-5
• 化学式: C₂₄H₃₂OSi₂
• 分子量: 392.688
• InChiKey: CVGQUWPFUSIOOM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.19
• 重原子数：
  27
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  Tert-butyl-[1-[2-[2-[dimethyl(phenyl)silyl]ethynyl]phenyl]ethenoxy]-dimethylsilane 在 platinum(II) chloride 作用下， 以 甲苯 为溶剂， 生成 、 Tert-butyl-[4-[dimethyl(phenyl)silyl]naphthalen-1-yl]oxy-dimethylsilane
  参考文献：
  名称：

  Transition-metal-promoted 6-endo-dig cyclization of aromatic enynes: rapid synthesis of functionalized naphthalenes

  摘要：

  Transition-metal-mediated cyclization of aromatic enynes provides high yields of substituted naphthalene compounds. The reaction can tolerate a wide range of substituents on both the olefin and the alkyne. The most useful catalysts were found to be [Rh(CO)(2)Cl](2), PdCl2 and PtCl2. In addition, a facile silyl migration occurs when the acetylene is substituted with a triorganosilyl group affording 4-silyl-naplithalenes. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)01146-7
• 作为产物：
  描述：

  2'-溴苯乙酮 在 二(氰基苯)二氯化钯 、 三叔丁基膦 三乙胺 作用下， 以 二氯甲烷 为溶剂， 生成 Tert-butyl-[1-[2-[2-[dimethyl(phenyl)silyl]ethynyl]phenyl]ethenoxy]-dimethylsilane
  参考文献：
  名称：

  Transition-metal-promoted 6-endo-dig cyclization of aromatic enynes: rapid synthesis of functionalized naphthalenes

  摘要：

  Transition-metal-mediated cyclization of aromatic enynes provides high yields of substituted naphthalene compounds. The reaction can tolerate a wide range of substituents on both the olefin and the alkyne. The most useful catalysts were found to be [Rh(CO)(2)Cl](2), PdCl2 and PtCl2. In addition, a facile silyl migration occurs when the acetylene is substituted with a triorganosilyl group affording 4-silyl-naplithalenes. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)01146-7

文献信息

• Transition-metal-promoted 6-endo-dig cyclization of aromatic enynes: rapid synthesis of functionalized naphthalenes
  作者：John W Dankwardt

  DOI：10.1016/s0040-4039(01)01146-7

  日期：2001.8

  Transition-metal-mediated cyclization of aromatic enynes provides high yields of substituted naphthalene compounds. The reaction can tolerate a wide range of substituents on both the olefin and the alkyne. The most useful catalysts were found to be [Rh(CO)(2)Cl](2), PdCl2 and PtCl2. In addition, a facile silyl migration occurs when the acetylene is substituted with a triorganosilyl group affording 4-silyl-naplithalenes. (C) 2001 Elsevier Science Ltd. All rights reserved.