Reactive Blue 19 vinyl sulfone | 14541-90-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: Reactive Blue 19 vinyl sulfone
• 英文别名: Uniblue A sodium salt；acid blue 215；uniblue A；Uniblu-A；sodium;1-amino-4-(3-ethenylsulfonylanilino)-9,10-dioxoanthracene-2-sulfonate
• CAS: 14541-90-3
• 化学式: C₂₂H₁₅N₂O₇S₂*Na
• 分子量: 506.492
• InChiKey: ANOULJGZTVOIFB-UHFFFAOYSA-M

物化性质

• 熔点：
  >300 °C(lit.)
• 稳定性/保质期：

  遵照规定使用和储存，则不会发生分解。

计算性质

• 辛醇/水分配系数(LogP)：
  -0.39
• 重原子数：
  34
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  180
• 氢给体数：
  2
• 氢受体数：
  9

安全信息

• 危险品标志：
  Xn
• 危险类别码：
  R22
• WGK Germany：
  3

SDS

Name:	Uniblue A Sodium Salt 98% (UV-VIS) Material Safety Data Sheet
Synonym:	None Known
CAS:	14541-90-3

Section 1 - Chemical Product MSDS Name:Uniblue A Sodium Salt 98% (UV-VIS) Material Safety Data Sheet
Synonym:None Known

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Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
14541-90-3	Uniblue A Sodium Salt, (UV-VIS)	98	238-573-6

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

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Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

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Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
Use agent most appropriate to extinguish fire.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

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Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels.
Exposure Limits CAS# 14541-90-3: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Powder
Color: dark blue
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C22H15N2NaO7S2
Molecular Weight: 506.48

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, sodium oxide, sulfur oxides (SOx), including sulfur oxide and sulfur dioxide.
Hazardous Polymerization: Has not been reported

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 14541-90-3 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Uniblue A Sodium Salt, (UV-VIS) - Not listed by ACGIH, IARC, or NTP.

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

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Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 14541-90-3: No information available.
Canada
CAS# 14541-90-3 is listed on Canada's DSL List.
CAS# 14541-90-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 14541-90-3 is listed on the TSCA inventory.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  Reactive Blue 19 vinyl sulfone 在 水 作用下， 生成 Reactive blue 19 alcohol
  参考文献：
  名称：

  非离子表面活性剂对乙烯基砜活性染料水解的影响

  摘要：

  非离子表面活性剂广泛用于活性染料的染色过程中，并且表面活性剂和活性染料之间的相互作用会影响活性染料的水解性能。在这项研究中，使用活性艳蓝KN-R（CI活性蓝19）作为模型染料，并选择脂肪醇聚氧乙烯醚（AEO-9）作为模型非离子表面活性剂。首先通过紫外分光光度法研究水溶液中的相互作用，然后使用高效液相色谱法研究表面活性剂浓度对KN-R水解行为的影响。在临界胶束浓度以下，表面活性剂用作分散剂。活性染料的水解加快。但是，当表面活性剂的浓度高于其临界胶束浓度时，染料溶解在胶束相中，这可以从吸光度强度和最大吸光度波长的变化中看出。这导致活性染料的水解减慢。这些发现对于理解非离子表面活性剂的浓度对乙烯基砜反应性染料水解的影响是有用的。

  DOI：

  10.1007/s11743-015-1726-2
• 作为产物：
  描述：

  reactive blue 19 在 fatty alcohol-polyoxyethylene ether 作用下， 以 aq. buffer 为溶剂， 反应 0.08h， 生成 Reactive Blue 19 vinyl sulfone
  参考文献：
  名称：

  非离子表面活性剂对乙烯基砜活性染料水解的影响

  摘要：

  非离子表面活性剂广泛用于活性染料的染色过程中，并且表面活性剂和活性染料之间的相互作用会影响活性染料的水解性能。在这项研究中，使用活性艳蓝KN-R（CI活性蓝19）作为模型染料，并选择脂肪醇聚氧乙烯醚（AEO-9）作为模型非离子表面活性剂。首先通过紫外分光光度法研究水溶液中的相互作用，然后使用高效液相色谱法研究表面活性剂浓度对KN-R水解行为的影响。在临界胶束浓度以下，表面活性剂用作分散剂。活性染料的水解加快。但是，当表面活性剂的浓度高于其临界胶束浓度时，染料溶解在胶束相中，这可以从吸光度强度和最大吸光度波长的变化中看出。这导致活性染料的水解减慢。这些发现对于理解非离子表面活性剂的浓度对乙烯基砜反应性染料水解的影响是有用的。

  DOI：

  10.1007/s11743-015-1726-2

文献信息

• Phase-out-compliant fluorosurfactants: unique methimazolium derivatives including room temperature ionic liquids
  作者：M. Hummel、M. Markiewicz、S. Stolte、M. Noisternig、D. E. Braun、T. Gelbrich、U. J. Griesser、G. Partl、B. Naier、K. Wurst、B. Krüger、H. Kopacka、G. Laus、H. Huppertz、H. Schottenberger

  DOI：10.1039/c7gc00571g

  日期：——

  numerous protonated, or quaternized imidazoliums with chemospecific attachment of the fluoroponytail at the 2-mercapto functionality. The deprotonated primary target products represent valuable nitrogen heterocyclic bases, capable of further substitution, and salt or complex formation. Specific physicochemical characteristics that are relevant for phase and surface responsive behavior, e.g. critical micelle

  1-甲基-3 H-咪唑-2-硫酮（可大量获得的药物活性成分）的简便烷基化作用，可使获得的高质产率获得大量质子化或季铵化的咪唑鎓，并在2-巯基官能团上具有化学特异性的氟桥尾连接。去质子化的主要目标产物代表有价值的氮杂环碱，能够进一步取代以及形成盐或络合物。与相和表面响应行为相关的特定理化特性，例如研究了临界胶束浓度，疏油性，降低的水表面张力，泡沫的形成，微颗粒PTFE的乳化作用，以作为选定的代表，并将其与常见的含氟表面活性剂和离子液体的性能进行了比较。显着地发现，各个多氟烷基甲基咪唑鎓体系的碘抗衡离子与用作卤化物的σ-孔配偶体的1-碘全氟烷烃之间的卤素键极大地影响了所得分子加合物的溶解度分布。在新的含氟物质类别中进行了单晶X射线结构测定。令人惊讶的是，未发现氟原子沿着多氟化化合物中通常遇到的链的螺旋排列是主要的构象。相当，它们被表现出罕见的之字形（线性烷烃状）链构象的结构基序所取代。关键衍生物也接受了初步的生态毒理学测试。
• Identification of low molecular weight organic acids by ion chromatography/hybrid quadrupole time-of-flight mass spectrometry during Uniblu-A ozonation
  作者：Apollonia Amorisco、Vito Locaputo、Carlo Pastore、Giuseppe Mascolo

  DOI：10.1002/rcm.6429

  日期：2013.1.15

  The balance of organic nitrogen and sulfur during ozonation of organic pollutants often shows a lack of complete mineralization. It follows that polar and ionic by‐products are likely to be present that are difficult to identify by liquid chromatography/mass spectrometry (LC/MS).

  在有机污染物臭氧化过程中，有机氮和硫的平衡通常表明缺乏完整的矿化作用。因此，很可能会存在极性和离子副产物，很难通过液相色谱/质谱（LC / MS）进行鉴定。
• Characterization of carbonyl by-products during Uniblu-A ozonation by liquid chromatography/hybrid quadrupole time-of-flight/mass spectrometry
  作者：A. Amorisco、V. Locaputo、G. Mascolo

  DOI：10.1002/rcm.5045

  日期：2011.7.15

  Uniblu-OH ozonation has been investigated by liquid chromatography/electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS) employing a quadrupole time-of-flight mass spectrometer. The by-products were derivatized with 2,4-dinitrophenylhydrazine, allowing the formation of [M-H](-) ions of the derivatives in the electrospray source. Exact mass measurements of both the [M-H](-) ions and their

  已经通过采用四极杆飞行时间质谱仪的液相色谱/电喷雾串联质谱法（LC / ESI-MS / MS）研究了Uniblu-OH臭氧化反应产生的含羰基副产物的结构解析。用2，4-二硝基苯肼使副产物衍生化，从而在电喷雾源中形成衍生物的[MH]（-）离子。精确测量[MH]（-）离子及其产物离子的质量，可以确定十种副产物的元素式和相关结构。主要的降解途径是脱羧，然后进一步氧化。值得注意的是，采用的实验程序可以在Uniblu-OH臭氧化过程中鉴定出含氮和含硫的羰基副产物。该结果对于监测有机污染物臭氧化过程中有机氮和硫的平衡具有环境意义。这些原子实际上并没有完全矿化。
• Investigation of the Photodegradation of Reactive Blue 19 on P-25 Titanium Dioxide: Effect of Experimental Parameters
  作者：Faridah Abu Bakar、Jan-Yves Ruzicka、Ida Nuramdhani、Bryce E. Williamson、Meike Holzenkaempfer、Vladimir B. Golovko

  DOI：10.1071/ch14024

  日期：——

  The photocatalytic decolorization and degradation of an anthraquinone-based reactive dye, C.I. Reactive Blue 19, was carried out in laboratory-scale experiments with the systematic variation of several operational parameters, including electron acceptor (hydrogen peroxide) concentration, initial pH, use of buffer solution, aeration, and the specific chemical nature of the buffer solution. Photodegradation was performed under simulated natural light, and conditions were chosen to mimic those found in industry. Mineralization and decolorization were monitored by UV-vis spectroscopy and total organic carbon analysis, and kinetics were modelled using an in-series first-order combination mechanism. Reaction products were examined and monitored by high-resolution mass spectrometry. Under the conditions explored, the reaction rate was found to depend not only on pH and electron acceptor concentration, but also on the specific chemical nature of the buffer used.

  在实验室规模的实验中，对蒽醌基活性染料 C.I. 活性蓝 19 进行了光催化脱色和降解，系统地改变了几个操作参数，包括电子受体（过氧化氢）浓度、初始 pH 值、缓冲溶液的使用、通气和缓冲溶液的特定化学性质。光降解是在模拟自然光下进行的，选择的条件与工业中的条件相似。通过紫外-可见光谱和总有机碳分析对矿化和脱色过程进行了监测，并使用串联一阶组合机制对动力学进行了建模。反应产物通过高分辨率质谱进行检验和监测。在所探讨的条件下，发现反应速率不仅取决于 pH 值和电子受体浓度，还取决于所用缓冲液的特定化学性质。
• FUCHSIN DYE, PREPARATION METHOD AND USE THEREOF
  申请人：Dalian University of Technology

  公开号：EP2789657B1

  公开（公告）日：2016-06-01