2-苯基丙醛缩-1.2-丙二醇 | 67634-23-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-苯基丙醛缩-1.2-丙二醇
• 中文别名: 4-甲基-2-(1-苯基乙基)-1,3-二氧杂环戊烷；龙葵缩醛；4-甲基-2-(1-苯基乙基)-1,3-二氧戊环
• 英文名称: 4-Methyl-2-(1-phenylethyl)-1,3-dioxolane
• CAS: 67634-23-5
• 化学式: C₁₂H₁₆O₂
• mdl: MFCD00082224
• 分子量: 192.25
• InChiKey: KHLVXMUGPANNQD-UHFFFAOYSA-N

物化性质

• 沸点：
  259.8±15.0℃ (760 Torr)
• 密度：
  1.031±0.06 g/cm3 (20 ºC 760 Torr)
• 闪点：
  114.4±16.0℃
• LogP：
  2.30
• 物理描述：
  Colourless to pale yellow clear liquid / Green mushroom, chicken coop, new mown hay aroma
• 溶解度：
  Insoluble
• 折光率：
  1.502-1.508

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

制备方法与用途

生产方法如下：

将苯乙酮与一氯醋酸乙酯在乙醇钠的存在下进行反应，随后通过水解脱羧处理，获得 α-甲基苯乙醛。再将其与丙二醇脱水缩合，生成缩醛。

文献信息

• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：US20170096418A1

  公开（公告）日：2017-04-06

  The present disclosure relates to compounds which are useful as cooling sensation compounds.

  本公开涉及作为冷感化合物有用的化合物。
• Derivative of 2-cyclohexylpropanal and perfumery composition comprising the same
  申请人：KAO CORPORATION

  公开号：EP0358091A2

  公开（公告）日：1990-03-14

  2-Cyclohexylpropanal derivatives are disclosed. The derivatives are represented by the following formula (I): wherein P is a hydrogen atom and Q represents a group -CH=N-OH or a group -CH(OR)₂, wherein each R represents a lower alkyl group or two R's together form a lower alkylene group which may have a lower alkyl substituent, or P and Q together form a group wherein R′ is a lower alkyl group. The compounds possess floral, fruity, or green odors and are useful for prepering perfume compositions.

  公开了 2-环己基丙醛衍生物。这些衍生物由下式（I）表示： 其中 P 是氢原子，Q 代表一个基团-CH=N-OH 或一个基团-CH(OR)₂，其中每个 R 代表一个低级烷基或两个 R 共同形成一个低级亚烷基，该亚烷基可能具有一个低级烷基取代基，或 P 和 Q 共同形成一个基团 其中 R′为低级烷基。 这些化合物具有花香、果香或绿色气味，可用于香水组合物的预处理。
• Polycarbonate resin composition
  申请人：MITSUBISHI ENGINEERING-PLASTICS CORPORATION

  公开号：EP0753540A2

  公开（公告）日：1997-01-15

  A polycarbonate resin composition according to the present invention is suited to be used for medical supplies or appliances and shows a very low yellow discoloration when exposed to an ionizing radiation for sterilization. The polycarbonate resin composition comprises 100 parts by weight of a polycarbonate resin; 0.01 to 5 parts by weight of an aromatic compound containing oxy group or carbonyl group; and 0.01 to 5 parts by weight of at least one compound selected from the group consisting of: (A) a compound containing cyclic acetal group; (B) a sulfone compound; (C) a sulfoxide compound; (D) polyalkylene glycol, an ether of polyalkylene glycol or an ester of polyalkylene glycol; (E) a compound containing sulfonate group; and (F) an aromatic hydrocarbon-aldehyde resin.

  根据本发明的一种聚碳酸酯树脂组合物适合用于医疗用品或器具，在暴露于电离辐射灭菌时，黄色褪色程度很低。聚碳酸酯树脂组合物包括 100 重量份的聚碳酸酯树脂；0.01 至 5 重量份的含氧基或羰基的芳香族化合物；以及 0.(A) 含环缩醛基团的化合物；(B) 砜化合物；(C) 亚砜化合物；(D) 聚亚烷基二醇、聚亚烷基二醇的醚或聚亚烷基二醇的酯；(E) 含磺酸基团的化合物；(F) 芳香烃-醛树脂。
• Polycarbonate resin composition stabilized against radiation
  申请人：MITSUBISHI ENGINEERING-PLASTICS CORPORATION

  公开号：EP0794218A2

  公开（公告）日：1997-09-10

  The present invention relates to a polycarbonate resin composition comprising 100 parts by weight of a polycarbonate resin; 0.01 to 5 parts by weight of a compound containing oxymethylene unit, a compound containing oxymethylene unit having substituent or a cyclic ether compound having substituent.

  本发明涉及一种聚碳酸酯树脂组合物，该组合物包括 100 重量份的聚碳酸酯树脂； 0.01 至 5 重量份的含氧亚甲基单元的化合物、含氧亚甲基单元且具有取代基的化合物或 具有取代基的环醚化合物。

表征谱图