sec-butyl-isopropyl-methyl-amine | 74012-02-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: sec-butyl-isopropyl-methyl-amine
• 英文别名: sec-Butyl-isopropyl-methyl-amin；Methyl-isopropyl-sek.-butyl-amin；N-methyl-N-propan-2-ylbutan-2-amine
• CAS: 74012-02-5
• 化学式: C₈H₁₉N
• 分子量: 129.246
• InChiKey: VZVDQQRBKVOHDV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  N-甲基异丁胺 、 丙酮 在 水 、 铂 作用下， 生成 sec-butyl-isopropyl-methyl-amine
  参考文献：
  名称：

  Skita; Keil; Havemann, Chemische Berichte, 1933, vol. 66, p. 1400,1409

  摘要：

  DOI：

文献信息

• POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF
  申请人：GLINKA TOMASZ

  公开号：US20080318957A1

  公开（公告）日：2008-12-25

  Disclosed are compounds having polybasic functionalities. The compounds inhibit bacterial efflux pump inhibitors and are used in combination with an anti-bacterial agent to treat or prevent bacterial infections. These combinations can be effective against bacterial infections that have developed resistance to anti-bacterial agents through an efflux pump mechanism.

  揭示了具有多元碱功能的化合物。这些化合物抑制细菌外流泵抑制剂，并与抗菌剂结合使用以治疗或预防细菌感染。这些组合物可以有效对抗通过外流泵机制对抗菌剂产生抗药性的细菌感染。
• [EN] AZAINDOLE DERIVATIVES<br/>[FR] DÉRIVÉS AZAINDOLE
  申请人：VANTIA LTD

  公开号：WO2011051672A1

  公开（公告）日：2011-05-05

  The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (such as asthma or COPD); and methods of treating patients with such compounds; wherein R1 to R20 and A1 are as defined herein.

  本发明提供了公式(I)的化合物：包含此类化合物的组合物；此类化合物在治疗（如哮喘或慢性阻塞性肺病COPD）中的应用；以及使用此类化合物治疗患者的方法；其中R1至R20和A1如本文所述定义。
• [EN] SUBSTITUTED AMINOALKYLAZOLES AS MALARIAL ASPARTIC PROTEASE INHIBITORS<br/>[FR] AMINOALKYLAZOLES SUBSTITUÉS UTILISÉS COMME INHIBITEURS DE LA PROTÉASE ASPARTIQUE DU PALUDISME
  申请人：LATVIAN INST ORGANIC SYNTHESIS

  公开号：WO2017069601A1

  公开（公告）日：2017-04-27

  The present invention relates to novel aminoalkylazoles acting as inhibitors of malarial protease plasmepsin II. These can be used as medicines or as constituent of medicines for the treatment of malaria infection.

  本发明涉及作为疟疾蛋白酶质体酶II抑制剂的新型氨基烷基唑类化合物。这些化合物可用作治疗疟疾感染的药物或药物成分。
• 3-(4,5-Dihydroisoxaxol-5-yl)benzoylcyclohexenones and the use thereof as herbicides
  申请人：——

  公开号：US20030199699A1

  公开（公告）日：2003-10-23

  The invention relates to 3-(4,5-dihydroisoxazole-5-yl)benzoylcyclohexenones of the general formula (I), wherein the variables have the following meanings: R 1 , R 2 represents hydrogen, nitro, halogen, cyano, alkyl, haloalkyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkysulfonyl or C 1 -C 6 haloalkylsulfonyl; R 3 represents hydrogen, halogen or alkyl; R 4 represents hydrogen or alkyl; R 5 , R 6 represents hydrogen, halogen, cyano, nitro, alkyl, alkoxy, alkylthio, dialkylamino, phenyl, benzyl or carbonyl, wherein the 7 last residues can be substituted; R 11 represents optionally substituted cyclohexenone that is linked in the 2 position and that carries a hydroxy residue or derivatives thereof in the 1 position. The invention further relates to the agriculturally useful salts thereof, to methods for producing the 3-(4,5-dihydroisoxazole-5-yl)benzoylcyclohexenones, to agents that contain the inventive compound, and to the use of said derivatives or agents containing them for controlling undesired plants.

  该发明涉及通式（I）的3-(4,5-二氢异噁唑-5-基)苯甲酰环己烯酮，其中变量具有以下含义：R1，R2代表氢、硝基、卤素、氰基、烷基、卤代烷基、烷氧基、卤代烷氧基、烷硫基、卤代烷硫基、烷基磺酰基、卤代烷基磺酰基或C1-C6卤代烷基磺酰基；R3代表氢、卤素或烷基；R4代表氢或烷基；R5，R6代表氢、卤素、氰基、硝基、烷基、烷氧基、烷硫基、二烷基氨基、苯基、苄基或羰基，其中最后7个残基可以被取代；R11代表在2位连接的可选择取代的环己烯酮，在1位携带一个羟基残基或其衍生物。该发明还涉及其农业上有用的盐，生产3-(4,5-二氢异噁唑-5-基)苯甲酰环己烯酮的方法，含有该创新化合物的药剂，以及用于控制不受欢迎植物的衍生物或含有它们的药剂的用途。
• 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazole
  申请人：——

  公开号：US20030100590A1

  公开（公告）日：2003-05-29

  1 The invention relates to 3-(4,5-dihydroisoxazole-5-yl)benzoylpyrazole of the formula (I), wherein the variables have the following meanings: R 1 , R 1 represent hydrogen, nitro, halogen, cyano, alkyl, halogenalkyl, alkoxy, halogenalkoxy, alkylthio, halogenalkylthio, alkylsulfinyl, halogenalkylsulfinyl, alkylsulfonyl or halogenalkylsulfonyl; hydrogen, R 3 represents halogen or alkyl; R 4 represents hydrogen or alkyl; R 5 , R 6 represent hydrogen, halogen, cyano, nitro, alkyl, alkoxy, alkylthio, dialkylamino, phenyl R 3 or carbonyl, wherein the latter six groups can be substituted; R 7 represents halogen, cyano, hydroxy, alkyl, halogenalkyl, alkoxy, halogenalkoxy, alkylthio, halogenalkylthio, alkylsulfinyl, halogenalkylsulfinyl, alkylsulfonyl, halogenalkylsulfonyl, amino, alkylamino, dialkylamino, dialkoxymethyl, hydroxyiminoalkyl, alkoxyiminoalkyl or optionally substituted carbonyl; R 11 represents optionally substituted pyrazole that is bound in the 4 position and that carries a hydroxy group or a derivative thereof in the 5 position. The invention also relates to the agriculturally useful salts thereof, to methods and to intermediate products for preparing the 3-(4,5-dihydroisoxazole-5-yl)benzoylpyrazole, to agents containing them and to the use of said derivatives or the agents containing them for combatting undesired plants.

  本发明涉及式（I）的3-（4,5-二氢异噁唑-5-基）苯甲酰吡唑，其中变量具有以下含义：R1，R1代表氢，硝基，卤素，氰基，烷基，卤代烷基，烷氧基，卤代烷氧基，烷硫基，卤代烷硫基，烷基亚磺酰基，卤代烷基亚磺酰基，烷基磺酰基或卤代烷基磺酰基; 氢，R3代表卤素或烷基; R4代表氢或烷基; R5，R6代表氢，卤素，氰基，硝基，烷基，烷氧基，烷硫基，二烷基氨基，苯基R3或羰基，其中后六个基团可以被取代; R7代表卤素，氰基，羟基，烷基，卤代烷基，烷氧基，卤代烷氧基，烷硫基，卤代烷硫基，烷基亚磺酰基，卤代烷基亚磺酰基，烷基磺酰基，卤代烷基磺酰基，氨基，烷基氨基，二烷基氨基，二烷氧甲基，羟基亚氨基烷基，烷氧基亚氨基烷基或可选取代的羰基; R11代表在4位上结合的可选取代的吡唑，并在5位上携带羟基或其衍生物的吡唑。本发明还涉及其在农业上有用的盐，制备3-（4,5-二氢异噁唑-5-基）苯甲酰吡唑的方法和中间体，含有它们的制剂以及使用该衍生物或含有它们的制剂来对抗不良植物的用途。