2-（3-溴苯基）-3-（2,4-二甲氧基苯基）-4-噻唑烷酮 | 388592-44-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-（3-溴苯基）-3-（2,4-二甲氧基苯基）-4-噻唑烷酮
• 英文名称: 2-(3-Bromophenyl)-3-(2,4-dimethoxyphenyl)-1,3-thiazolidin-4-one
• CAS: 388592-44-7
• 化学式: C₁₇H₁₆BrNO₃S
• 分子量: 394.3
• InChiKey: MVWNPZYLNLATCH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  64.1
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• TREATMENT OF OTITIS MEDIA
  申请人：Research Institute at Nationwid Children's Hospita

  公开号：US20170275379A1

  公开（公告）日：2017-09-28

  A method of treating otitis media in a subject is described that includes administering to the subject a therapeutically effective amount of an Actin-Related Protein 2/3 Complex (Arp2/3) inhibitor. The role of Arp2/3 in otitis media was identified using comprehensive proteomic and metabolomic studies of otitis media using the chinchilla model.
• COMBINATION OF PHARMACOLOGICAL AND MICROFLUIDIC FEATURES FOR IMPROVED PLATELETS PRODUCTION
  申请人：PLATOD

  公开号：US20180104692A1

  公开（公告）日：2018-04-19

  The present invention relates to an ex vivo method for producing platelets including a combination of use of pharmacological substances and microfluidic device features, for high yield and high quality platelet production from megakaryocytes or their progenitors.