3,3-二(乙基磺酰基)戊烷 | 2217-59-6

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫代缩醛
• 中文名称: 3,3-二(乙基磺酰基)戊烷
• 英文名称: 3,3-bis-ethanesulfonyl-pentane
• 英文别名: 3,3-Bis-aethansulfonyl-pentan；γ.γ-Bis-aethylsulfon-pentan；3.3-Bis-(aethylsulfon)-pentan；Bis-(aethylsulfon)-diaethyl-methan；3,3-bis(ethylsulfonyl)-pentane；Tetronal；3,3-Bis(ethylsulfonyl)pentane
• CAS: 2217-59-6
• 化学式: C₉H₂₀O₄S₂
• 分子量: 256.387
• InChiKey: VTZYVPLHCQBWSP-UHFFFAOYSA-N

物化性质

• 沸点：
  452.4±28.0 °C(Predicted)
• 密度：
  1.169±0.06 g/cm3(Predicted)
• 溶解度：
  0.01 M

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  85
• 氢给体数：
  0
• 氢受体数：
  4

安全信息

• 海关编码：
  2904100000

文献信息

• ACROLEIN MANUFACTURING METHOD AND ACRYLIC ACID MANUFACTURING METHOD
  申请人：Aoki Takanori

  公开号：US20110087050A1

  公开（公告）日：2011-04-14

  The present invention relates to a method for producing acrolein, comprising step (1) of subjecting glycerol to dehydration reaction in the presence of a copper compound and a compound containing a heteroatom; step (2) of recovering acrolein generated in the dehydration reaction step (1); step (3) of recovering part or all of the copper compound which remained after the recovery of acrolein; step (4) of treating part or all of the recovered copper compound with at least one member selected from a group consisting of an oxidizing agent and acid; and step (5) of returning part or all of the copper compound treated in the above step to step (1); and a method for producing acrylic acid, comprising reacting acrolein obtained by the above method with molecular oxygen. The production method of the present invention enables efficient production of acrolein and acrylic acid from glycerol contained in plant oil and animal fats derived from carbon dioxide in air without depending on the oxidation of propylene derived from fossil resources.

  本发明涉及一种制备丙烯醛的方法，包括步骤（1）：在铜化合物和含有杂原子的化合物的存在下，将甘油进行脱水反应；步骤（2）：回收在脱水反应步骤（1）中生成的丙烯醛；步骤（3）：在回收丙烯醛后，回收部分或全部剩余的铜化合物；步骤（4）：用至少选自氧化剂和酸的一种成员处理部分或全部回收的铜化合物；步骤（5）：将上述步骤中处理的部分或全部铜化合物返回步骤（1）。本发明还涉及一种制备丙烯酸的方法，包括将通过上述方法获得的丙烯醛与分子氧反应。本发明的生产方法能够高效地从植物油和动物脂肪中含有的甘油中制备丙烯醛和丙烯酸，而不依赖于来自化石资源的丙烯氧化。
• Methods and compositions for treating cancer using P2RX2 inhibitors
  申请人：Flagship Pioneering Innovations V, Inc.

  公开号：US10457740B1

  公开（公告）日：2019-10-29

  The present invention provides methods for treating cancer using P2RX2 inhibitors, such as P2RX2 inhibitory antibodies, among others. The invention also features compositions containing P2RX2 inhibitors, methods of diagnosing patients with P2RX2-associated cancer, and methods of predicting the response of cancer in a subject to treatment with P2RX2 inhibitors.

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• Methods for treating cancer using GRM8 inhibitors
  申请人：Flagship Pioneering Innovations V, Inc.

  公开号：US10683352B1

  公开（公告）日：2020-06-16

  The present invention provides methods for treating cancer using mGluR8 inhibitors, such as mGluR8 inhibitory antibodies and small molecules. The invention also features compositions containing mGluR8 inhibitors, methods of diagnosing patients with mGluR8-associated cancer, and methods of predicting the response of cancer in a subject to treatment with mGluR8 inhibitors.

  本发明提供了使用mGluR8抑制剂（如mGluR8抑制抗体和小分子）治疗癌症的方法。本发明还包括含有 mGluR8 抑制剂的组合物、诊断 mGluR8 相关癌症患者的方法以及预测癌症对 mGluR8 抑制剂治疗的反应的方法。
• Methods and compositions for treating cancer using SERCA pump inhibitors
  申请人：Flagship Pioneering Innovations V, Inc.

  公开号：US11013717B1

  公开（公告）日：2021-05-25

  The present invention provides methods for treating cancer using sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) pump inhibitors, such as SERCA pump inhibitory antibodies, among others. The invention also features compositions containing SERCA pump inhibitors, methods of diagnosing patients with SERCA pump-associated cancer, and methods of predicting the response of cancer in a subject to treatment with SERCA pump inhibitors.

  本发明提供了使用肌浆/内质网Ca2+-ATP酶（SERCA）泵抑制剂（如SERCA泵抑制抗体等）治疗癌症的方法。本发明还包括含有 SERCA 泵抑制剂的组合物、诊断 SERCA 泵相关癌症患者的方法以及预测癌症对 SERCA 泵抑制剂治疗的反应的方法。
• Methods and compositions for treating cancer using serotonin receptor inhibitors
  申请人：Flagship Pioneering Innovations V, Inc.

  公开号：US11034751B1

  公开（公告）日：2021-06-15

  The present invention provides methods for treating cancer using serotonin receptor inhibitors, such as serotonin receptor inhibitory antibodies, among others. The invention also features compositions containing serotonin receptor inhibitors, methods of diagnosing patients with serotonin receptor-associated cancer, and methods of predicting the response of cancer in a subject to treatment with serotonin receptor inhibitors.

  本发明提供了使用血清素受体抑制剂（如血清素受体抑制抗体等）治疗癌症的方法。本发明还包括含有血清素受体抑制剂的组合物、诊断血清素受体相关癌症患者的方法，以及预测癌症对血清素受体抑制剂治疗的反应的方法。