3,4-二氯-n-(4-氯苯基)苯磺酰胺 | 640-59-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 3,4-二氯-n-(4-氯苯基)苯磺酰胺
• 英文名称: 3,4,4'-Trichlorbenzolsulfonanilid
• 英文别名: 3,4-dichloro-N-(4-chlorophenyl)benzenesulfonamide；Reseptyl
• CAS: 640-59-5
• 化学式: C₁₂H₈Cl₃NO₂S
• 分子量: 336.626
• InChiKey: WHONBYFXHJXDJB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  54.6
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 海关编码：
  2935009090

文献信息

• COMPOSITIONS FOR THE TREATMENT OF BURNS AND EXTERNAL ULCERS AND A PROCESS FOR THE PREPARATION THEREOF
  申请人：Lukacs, Karoly

  公开号：EP0971707A1

  公开（公告）日：2000-01-19
• BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS
  申请人：Arrow Therapeutics Limited

  公开号：EP1239852A2

  公开（公告）日：2002-09-18
• [EN] COMPOSITIONS FOR THE TREATMENT OF BURNS AND EXTERNAL ULCERS AND A PROCESS FOR THE PREPARATION THEREOF<br/>[FR] COMPOSITIONS DE TRAITEMENT DE BRULURES ET DE PLAIES EXTERNES ET PROCEDE DE PREPARATION ASSOCIE
  申请人：LUKÁCS, Károly

  公开号：WO1998044914A1

  公开（公告）日：1998-10-15

  (EN) The invention relates to compositions for treating burns and external ulcers containing as active ingredient the mixture of one or more sulfonamides, a macrolide antibiotic or chloramphenicol or thiamphenicol, together with zinc oxide, camomile oil and azulene.(FR) L'invention concerne des composition de traitement de brûlures et de plaies externes, contenant en tant que principe actif un mélange d'un ou de plusieurs sulfonamides, d'un antibiotique macrolide ou de chloramphénicol ou thiamphénicol, avec de l'oxyde de zinc, de l'huile de camomille et de l'azulène.
• [EN] ENZYME INHIBITORS<br/>[FR] INHIBITEURS D'ENZYMES
  申请人：ARROW THERAPEUTICS LTD

  公开号：WO2001028537A2

  公开（公告）日：2001-04-26

  Bissulfonamide derivatives of formula (I) are capable of inhibiting: a) the biosynthesis of aromatic amino acids via the shikimate pathway and b) the catabolism of quinic acid, wherein: Ar is an aryl or heteroaryl group; R1 and R2 are the same or different and each represent hydrogen or alkyl or R1 and R2 together form a C1-C3 alkylene group, -CO- or -CS-; and R3 and R4 are the same or different and each represent -alkyl-aryl, -alkyl-heteroaryl, -alkenyl-aryl, -alkenyl-heteroaryl, -alkynyl-aryl-alkynyl-heterorayl, aryl or heteroaryl.