3,5,4'-三氯-联苯基-4-基胺 | 380599-69-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 3,5,4'-三氯-联苯基-4-基胺
• 英文名称: 3,5,4'-trichloro-biphenyl-4-ylamine
• 英文别名: 3.5.4'-Trichlor-4-amino-diphenyl；3,5,4'-Trichlor-biphenyl-4-ylamin；3,4',5-Trichloro[1,1'-biphenyl]-4-amine；2,6-dichloro-4-(4-chlorophenyl)aniline
• CAS: 380599-69-9
• 化学式: C₁₂H₈Cl₃N
• 分子量: 272.561
• InChiKey: PBZNYRCFZDOOJI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3,5,4'-三氯-联苯基-4-基胺 在 硫酸 、 sodium nitrite 、 copper(l) chloride 作用下， 以42%的产率得到3,4,4',5-四氯联苯
  参考文献：
  名称：

  Synthesis of polychlorinated biphenyls (PCBs) using the Suzuki-coupling

  摘要：

  An improved synthesis of polychlorinated biphenyls (PCBs) utilizing a palladium-catalyzed cross-coupling reaction (Suzuki-coupling) is described. The coupling of (chlorinated) aryl boronic acids 1-3 with bromochlorobenzenes 4 using the standard conditions of the Suzuki-coupling gave the desired PCB congeners 5-7 in good to excellent yields. The self-coupling product of the aryl boronic acids is the major impurity of this reaction. 3,4,5-trichlorophenyl derivatives such as 10 can be synthesized by coupling of an aryl boronic acid with the corresponding bromochloroaniline 8. The approach offers the advantage of high selectivity and good yields compared to conventional methods such as the Cadogan reaction and allows the use of less toxic starting materials. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0045-6535(00)00546-4
• 作为产物：
  描述：

  N-(3,5,4'-trichloro-biphenyl-2-yl)-acetamide 在 盐酸 作用下， 生成 3,5,4'-三氯-联苯基-4-基胺
  参考文献：
  名称：

  Scarborough; Waters, Journal of the Chemical Society, 1926, p. 560

  摘要：

  DOI：

文献信息

• NOVEL STRATEGIES, LINKERS AND COORDINATION POLYMERS FOR HIGH-PERFORMANCE SORBENTS
  申请人：Matzger Adam J.

  公开号：US20090062498A1

  公开（公告）日：2009-03-05

  A linking ligand compound includes three bidentate chemical moieties distributed about a central chemical moiety. Another linking ligand compound includes a bidentate linking ligand and a monodentate chemical moiety. Coordination polymers include a plurality of metal clusters linked together by residues of the linking ligand compounds.

  一个连接配体化合物包括分布在中心化学基团周围的三个双齿化学基团。另一个连接配体化合物包括一个双齿连接配体和一个单齿化学基团。配位聚合物包括由连接配体化合物的残基连接在一起的多个金属簇。
• Novel Strategies, Linkers and Coordination Polymers for High-Performance Sorbents
  申请人：THE REGENTS OF THE UNIVERSITY OF MICHIGAN

  公开号：US20130237411A1

  公开（公告）日：2013-09-12

  A linking ligand compound includes three bidentate chemical moieties distributed about a central chemical moiety. Another linking ligand compound includes a bidentate linking ligand and a monodentate chemical moiety. Coordination polymers include a plurality of metal clusters linked together by residues of the linking ligand compounds.

  一个连接配体化合物包括分布在中心化学基团周围的三个双齿化学基团。另一个连接配体化合物包括一个双齿连接配体和一个单齿化学基团。配位聚合物包括由连接配体化合物的残基连接在一起的多个金属簇。
• Hinkel; Hey, Journal of the Chemical Society, 1928, p. 2787,2789
  作者：Hinkel、Hey

  DOI：——

  日期：——
• US8383545B2
  申请人：——

  公开号：US8383545B2

  公开（公告）日：2013-02-26
• US9132411B2
  申请人：——

  公开号：US9132411B2

  公开（公告）日：2015-09-15