2-(9-Anthryl)ethyl chloroformate | 129948-83-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 2-(9-Anthryl)ethyl chloroformate
• 英文别名: Chloroformic acid 2-(9-anthryl)ethyl ester；2-anthracen-9-ylethyl carbonochloridate
• CAS: 129948-83-0
• 化学式: C₁₇H₁₃ClO₂
• 分子量: 284.742
• InChiKey: KWCQFAYPSAKDMW-UHFFFAOYSA-N

物化性质

• 沸点：
  457.6±24.0 °C(Predicted)
• 密度：
  1.283±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-(9-Anthryl)ethyl chloroformate 生成 9-(2-羟乙基)蒽
  参考文献：
  名称：

  FAULKNER, ARTHUR J.;VEENING, HANS;BECKER, HANS-DIETER, ANAL. CHEM., 63,(1991) N, C. 292-296

  摘要：

  DOI：

文献信息

• 9-Anthrylalkyl compounds, their preparation and their use
  申请人：Eka Nobel Aktiebolag

  公开号：EP0365495A2

  公开（公告）日：1990-04-25

  New 9-anthrylalkyl compounds having the general formula wherein R is hydrogen or an alkyl group, whereby, however, not more than one of the groups R is an alkyl group; R₁ is hydrogen, lower alkyl, halogen or nitro; n is an integer of from 1 to 7, whereby ,however, the total number of carbon atoms in the group -CHR-(CHR)n- does not exceed 8; and X is halogen, an azide group or a succinimidyl group. The new compounds are prepared from 9-anthrylalcohols which are reacted with a compound X-CO-X wherein X is a halogen, and then optionally with compounds giving azide or succinimidyl group. The compounds are used as derivatiza­tion reagents for separation and detection purposes. Intermediates for preparation of the above defined 9-anthrylalkyl compounds wherein one R is an alkyl group are 9-anthrylalcohols with the group -CHR-(CHR)n-OH, wherein one R is an alkyl group.

  通式如下的新型 9-蒽烷基化合物 其中，R 是氢或烷基，但是，R 中不超过一个基团是烷基；R₁ 是氢、低级烷基、卤素或硝基；n 是 1 到 7 的整数，但是，基团 -CHR-(CHR)n- 中的碳原子总数不超过 8；X 是卤素、叠氮基团或琥珀酰亚胺基团。 新化合物由 9-蒽醇制备而成，9-蒽醇先与化合物 X-CO-X 反应，其中 X 为卤素，然后再与含有叠氮基团或琥珀酰亚胺基团的化合物反应。这些化合物可用作衍生试剂，用于分离和检测。 制备上述定义的 9-蒽烷基化合物（其中一个 R 是烷基）的中间体是基团为 -CHR-(CHR)n-OH（其中一个 R 是烷基）的 9-蒽醇。
• Thermally induced substrate release via intramolecular cyclizations of Amino esters and Amino carbonates
  作者：Ralph J. Knipp、Rosendo Estrada、Palaniappan Sethu、Michael H. Nantz

  DOI：10.1016/j.tet.2014.03.092

  日期：2014.5

  The relative cleavage of an alcohol from a panel of amino esters and amino carbonates via intramolecular cyclization was examined as a mechanism for substrate release. Thermal stability at 37 degrees C was observed only for the seven-membered ring progenitors. Applicability of the approach was illustrated by delta-lactam formation within a poly(dimethylsiloxane) microchannel for release of a captured fluorescent probe. (C) 2014 Elsevier Ltd. All rights reserved.
• 2-(9-Anthryl)ethyl chloroformate: a precolumn derivatizing reagent for polyamines determined by liquid chromatography and fluorescence detection
  作者：Arthur J. Faulkner、Hans. Veening、Hans Dieter. Becker

  DOI：10.1021/ac00003a020

  日期：1991.2.1

  This paper describes the use of a new compound, 2-(9-anthryl)ethyl chloroformate (AEOC), as a sensitive and convenient precolumn, fluorophoric, derivatizing reagent for polyamines (putrescine, cadaverine, spermidine, and spermine) determined by liquid chromatography. Experiments were carried out to determine maximum fluorescence excitation and emission wavelengths, optimum reaction pH, calibration curves, and minimum detection limits for each of the AEOC-derivatized polyamines. The procedure was applied successfully to serum samples from healthy individuals and cancer patients and provides complete separation of derivatized polyamines from serum hydrolysate components. Detection limits for three of the AEOC-derivatized polyamines are more favourable than those reported previously for polyamines derivatized with 9-fluorenylmethyl chloroformate (FMOC).
• FAULKNER, ARTHUR J.;VEENING, HANS;BECKER, HANS-DIETER, ANAL. CHEM., 63,(1991) N, C. 292-296
  作者：FAULKNER, ARTHUR J.、VEENING, HANS、BECKER, HANS-DIETER

  DOI：——

  日期：——
• JPH02111745A
  申请人：——

  公开号：JPH02111745A

  公开（公告）日：1990-04-24