2-amino-5-chloro-N-(bis-2-methylpropyl-λ⁴-sulfanylidene)-3-methyl-benzamide | 1422677-54-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-amino-5-chloro-N-(bis-2-methylpropyl-λ⁴-sulfanylidene)-3-methyl-benzamide
• 英文别名: 2-amino-N-[bis(2-methylpropyl)-λ⁴-sulfanylidene]-5-chloro-3-methylbenzamide；2-amino-5-chloro-N-(bis-2-methylpropyl-λ⁴-sulfanylidene)-3-methylbenzamide；2-amino-N-[bis(2-methylpropyl)-lambda4-sulfanylidene]-5-chloro-3-methylbenzamide；2-amino-N-[bis(2-methylpropyl)-λ4-sulfanylidene]-5-chloro-3-methylbenzamide
• CAS: 1422677-54-0
• 化学式: C₁₆H₂₅ClN₂OS
• 分子量: 328.906
• InChiKey: JEPWJVABCDFIGX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  74.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  6-chloro-8-methyl-1H-benzo[d][1,3]oxazine-2,4-dione 、 bis-2-methylpropyl sulfinium sulfate 在 S,S-dimethyl-S-aminosulfinium sulfate 作用下， 以 二氯甲烷 为溶剂， 反应 1.5h， 以69%的产率得到2-amino-5-chloro-N-(bis-2-methylpropyl-λ⁴-sulfanylidene)-3-methyl-benzamide
  参考文献：
  名称：

  [EN] ANILINE TYPE COMPOUNDS
  [FR] COMPOSÉS DE TYPE ANILINES

  摘要：

  本发明涉及以下式(I)的化合物，其中R1和R2彼此独立地为氢、C1-C10-烷基、C1-C10-卤代烷基、C3-C10-环烷基、C3-C10-卤代环烷基、C2-C10-烯基、C2-C10-卤代烯基或者一起代表一个脂肪链等；R3为卤素、氰基、C1-C8-烷基、C1-C8-卤代烷基、C3-C8-环烷基、C3-C8-卤代环烷基、C2-C8-烯基、C2-C8-卤代烯基、C1-C8-烷氧基、苯基等；R4为氢、C1-C10-烷基、C1-C10-卤代烷基、C3-C8-环烷基、C3-C8-卤代环烷基、C2-C10-烯基、C2-C10-卤代烯基、苯基等；t为0或1；p为0、1、2、3或4。本发明还涉及一种制备上述式(I)化合物的方法，包括将式(II)的化合物与式(III)或(IV)的化合物反应：其中t、p、R1、R3、R3和R4如权利要求1至6中的任一所定义，A-是至少在水中标准条件下具有至少10的pΚB值的阴离子的当量。

  公开号：

  WO2013024008A1

文献信息

• [EN] PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBONYLCHLORIDE COMPOUNDS<br/>[FR] PROCÉDÉ DE PRÉPARATION DE COMPOSÉS 1H-PYRAZOLE-5-CARBONYLCHORURES N-SUBSTITUÉS
  申请人：BASF SE

  公开号：WO2013024007A1

  公开（公告）日：2013-02-21

  The present invention relates to a process for preparing an N-substi- tuted 1 H-pyrazole-5-carbonylchloride compound of the formula (I) comprising the steps of i) deprotonating a compound of the formula (II) with a base selected from lithium-organic base having a carbon or nitrogen bound lithium or with a magnesium-organic base having a carbon bound magnesium; and ii) subjecting the product obtained in step (i) to a chlorocarbonylation by reacting it with a reagent selected from the group consisting of phosgene or a phosgene equivalent, to obtain a compound of formula (I).

  本发明涉及一种制备式(I)N-取代1H-吡唑-5-羰基氯化物的过程，包括以下步骤：i) 用选择自碳或氮与锂结合的有机锂碱或碳与镁结合的有机镁碱的碱去质子化式(II)化合物；和ii) 将步骤(i)中获得的产物经氯羰基化反应，与磷酰氯或磷酰氯等效物中选择的试剂反应，以获得式(I)化合物。
• [EN] PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLATE COMPOUNDS AND DERIVATIVES THEREOF<br/>[FR] PROCÉDÉ DE PRÉPARATION D'UN COMPOSÉ N-1 H-PYRAZOLE SUBSTITUÉ-5-CARBOXYLATE ET DE SES DÉRIVÉS
  申请人：BASF SE

  公开号：WO2013076092A1

  公开（公告）日：2013-05-30

  The present invention relates to a process for preparing an N-substituted 1 H-pyrazole- 5- carboxylate compound of the formula (l-A) comprising the steps of i) deprotonating a compound of the formula (II) in which the variables R1, R2 and r are each as defined in the description and the claims, with a magnesium-organic base having a carbon bound magnesium; and ii) subjecting the product obtained in step (i) to a carbonylation by reacting it with a reagent selected from the group consisting carbon dioxide or a carbon dioxide equivalent, to obtain a compound of formula (l-A); and it relates to further conversions to yield a N-substituted 1H-pyrazole-5-carbonyl chloride compound of the formula (I).

  本发明涉及一种制备式(l-A)的N-取代1 H-吡唑-5-羧酸酯化合物的过程，包括以下步骤：i) 用具有碳键镁的镁有机碱去质子化式(II)的化合物，其中变量R1、R2和r如描述和索赔中定义，并ii) 将步骤(i)中得到的产物经过羰基化反应，与选择自二氧化碳或二氧化碳等效物的试剂反应，得到式(l-A)的化合物；并且涉及进一步的转化以产生式(I)的N-取代1H-吡唑-5-羰基氯化物化合物。
• Aniline Type Compounds
  申请人：Koerber Karsten

  公开号：US20140155451A1

  公开（公告）日：2014-06-05

  The present invention relates to compounds of the formula (I) wherein R 1 and R 2 independently of one another are hydrogen, C 1 -C 10 -alkyl, C 1 -C 10 -haloalkyl, C 3 -C 10 -cycloalkyl, C 3 -C 10 -halocycloalkyl, C 2 -C 10 -alkenyl, C 2 -C 10 -haloalkenyl or together represent an aliphatic chain, or the like; R 3 is halogen, cyano, C 1 -C 8 -alkyl, C 1 -C 8 -haloalkyl, C 3 -C 8 -cycloalkyl, C 3 -C 8 -halocycloalkyl, C 2 -C 8 -alkenyl, C 2 -C 8 -haloalkenyl, C 1 -C 8 -alkoxy, phenyl, or the like; R 4 is hydrogen, C 1 -C 10 -alkyl, C 1 -C 10 -haloalkyl, C 3 -C 8 -cycloalkyl, C 3 -C 8 -halocycloalkyl, C 2 -C 10 -alkenyl, C 2 -C 10 -haloalkenyl, phenyl, or the like; t is 0 or 1; p is 0, 1, 2, 3 or 4. The present invention also relates to a process for preparing a compound of the formula (I) which comprises reacting a compound of the formula II with a compound of the formulae III or IV: where t, p, R 1 R 3 , R 3 and R 4 are as defined in any of claims 1 to 6 and where A − is an equivalent of an anion having a pK B of at least 10 (determined under standard conditions in water).

  本发明涉及式(I)的化合物，其中R1和R2独立地是氢，C1-C10-烷基，C1-C10-卤代烷基，C3-C10-环烷基，C3-C10-卤代环烷基，C2-C10-烯基，C2-C10-卤代烯基或一起代表脂肪链等；R3是卤素，氰基，C1-C8-烷基，C1-C8-卤代烷基，C3-C8-环烷基，C3-C8-卤代环烷基，C2-C8-烯基，C2-C8-卤代烯基，C1-C8-烷氧基，苯基或类似物；R4是氢，C1-C10-烷基，C1-C10-卤代烷基，C3-C8-环烷基，C3-C8-卤代环烷基，C2-C10-烯基，C2-C10-卤代烯基，苯基或类似物；t为0或1；p为0、1、2、3或4。本发明还涉及一种制备式(I)化合物的方法，该方法包括将式II的化合物与式III或IV的化合物反应：其中t、p、R1、R3、R3和R4如权利要求1至6中的任何一项中所定义，A-是至少具有10的pKB（在水中标准条件下测定）的阴离子当量。
• Process for preparing N-substituted 1H-pyrazole-5-carbonylchloride compounds
  申请人：Körber Karsten

  公开号：US20140163234A1

  公开（公告）日：2014-06-12

  The present invention relates to a process for preparing an N-substituted 1H-pyrazole-5-carbonylchloride compound of the formula (I) in which R 1 is hydrogen, halogen, cyano, C 1 -C 6 -alkyl, C 1 -C 6 -fluoroalkyl, C 3 -C 8 -cycloalkyl, C 3 -C 8 -fluorocycloalkyl, C 2 -C 6 -alkenyl, C 2 -C 6 -fluoroalkenyl, C 1 -C 6 -alkoxy, C 1 -C 6 -fluoroalkoxy, C 1 -C 4 -fluoroalkoxy-C 1 -C 4 -alkyl, phenyl and the like; each R 2 is independently selected from halogen, C 1 -C 6 -alkyl, C 1 -C 6 -fluoroalkyl, C 3 -C 8 -cycloalkyl, C 3 -C 8 -fluorocycloalkyl, C 2 -C 6 -alkenyl, C 2 -C 6 -fluoroalkenyl, C 1 -C 6 -alkoxy, phenyl and the like; r is 0, 1, 2, 3 or 4; comprising the steps of i) deprotonating a compound of the formula (II) in which the variables R 1 , R 2 and r are each as defined above, with a base selected from lithium-organic base having a carbon or nitrogen bound lithium or with a magnesium-organic base having a carbon bound magnesium; and ii) subjecting the product obtained in step (i) to a chlorocarbonylation by reacting it with a reagent selected from the group consisting of phosgene or a phosgene equivalent, to obtain a compound of formula (I).

  本发明涉及一种制备式(I)的N-取代1H-吡唑-5-羰基氯化物化合物的方法，其中R1是氢、卤素、氰基、C1-C6烷基、C1-C6氟代烷基、C3-C8环烷基、C3-C8氟代环烷基、C2-C6烯基、C2-C6氟代烯基、C1-C6烷氧基、C1-C6氟代烷氧基、C1-C4氟代烷氧基-C1-C4烷基、苯基等；每个R2分别选自卤素、C1-C6烷基、C1-C6氟代烷基、C3-C8环烷基、C3-C8氟代环烷基、C2-C6烯基、C2-C6氟代烯基、C1-C6烷氧基、苯基等；r为0、1、2、3或4；包括以下步骤：i）用碳或氮与锂结合的有机锂碱或碳与镁结合的有机镁碱中的一种碱去质子化式(II)的化合物，其中变量R1、R2和r如上所定义；ii）将步骤(i)中得到的产物与光气或光气等效物组成的试剂反应，进行氯羰基化反应，得到式(I)的化合物。
• PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS
  申请人：BASF SE

  公开号：US20150250173A1

  公开（公告）日：2015-09-10

  The present invention relates to pesticidal mixtures comprising as active compounds 1) at least one pesticidally active anthranilamide compound of formula (I) wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and k are as defined in the description; and 2) at least one fungicidally active compound II selected from a group F comprising azoles, strobilurins, carboxamides, carbamates, heterocyclic and various other compounds as defined in the description, in synergistically effective amounts. The invention relates further to methods and use of these mixtures for combating and controlling insects, acarids or nematodes and harmful fungi in and on plants, and for protecting such plants being infested with pests, especially also for protecting plant propagation material, such as seeds.

  本发明涉及杀虫剂混合物，包括以下活性化合物：1）至少一种式(I)的杀虫活性的蒽酰胺化合物，其中R1，R2，R3，R4，R5，R6，R7和k如描述中所定义；2）至少一种从F组中选择的具有杀菌活性的化合物II，该组包括如描述中所定义的唑类，斑点灵，羧酰胺，氨基甲酸酯，杂环和其他化合物，其在协同有效量下。本发明还涉及使用这些混合物的方法和用于在植物内外控制和防治昆虫，螨和线虫以及有害真菌，并保护被害虫侵染的植物，特别是保护植物繁殖材料，例如种子。