To provide a diagnostic and therapeutic medicament, a bombesin analog peptide antagonist conjugate is provided which has general Formula (I), wherein A is a metal chelator comprising at least one radionuclide metal, B is a spacer linked to N-terminal of C or a covalent bond and C is a bombesin analog peptide antagonist having a sequence as claimed, where further x is an integer from 1 to 3 and n is an integer from 1 to 6.
[A-(B)
n
]
x
—C (I)
提供一种诊断和治疗药物,该药物是一种炸弹素类似物肽拮抗剂共轭物,具有通式(I),其中A是至少含有一种放射性核素
金属的
金属
螯合剂,B是连接到C的N-末端或共价键的间隔物,C是具有所述序列的炸弹素类似物肽拮抗剂,其中x是1到3的整数,n是1到6的整数。[A-(B)n]x—C (I)