4-[(Pyridin-1-ium-4-ylamino)methyl]benzoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-[(Pyridin-1-ium-4-ylamino)methyl]benzoate
• 化学式: C13H12N2O2
• mdl: MFCD09950171
• 分子量: 228.25
• InChiKey: ZJJLFCGQWMKQPM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.076
• 拓扑面积：
  62.2
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Pyridine and quinoline derivatives, processes for their manufacture and their use as angiotensin II antagonists
  申请人：ZENECA LIMITED

  公开号：EP0499415A1

  公开（公告）日：1992-08-19

  The invention concerns pharmaceutically useful compounds of the formula I, in which R¹, R², R³, R⁴, R⁵, R⁶, R⁷, Rz, X and Z have the various meanings defined herein, and their non-toxic salts, and pharmaceutical compositions containing them. The novel compounds are of value in treating conditions such as hypertension and congestive heart failure. The invention further concerns processes for the manufacture of the novel compounds and the use of the compounds in medical treatment.

  本发明涉及式 I 的药用化合物，其中 R¹、R²、R³、R⁴、R⁵、R⁶、R⁷、Rz、X 和 Z 具有本文定义的各种含义，以及它们的无毒盐和含有它们的药物组合物。这些新型化合物具有治疗高血压和充血性心力衰竭等疾病的价值。本发明还涉及新型化合物的生产工艺以及这些化合物在医疗中的应用。
• LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT
  申请人：Chi Mei Corporation

  公开号：US20170152443A1

  公开（公告）日：2017-06-01

  A liquid crystal alignment agent allowing formation of an LCD element having good reliability and less residual image, a liquid crystal alignment film, and an LCD element having the liquid crystal alignment film are shown. The liquid crystal alignment agent includes a polymer (A), a photosensitive polysiloxane (B), and a solvent (C). The polymer (A) is obtained by reacting a mixture that includes a tetracarboxylic dianhydride component (a-1) and a diamine component (a-2). The photosensitive polysiloxane (B) is obtained by reacting a polysiloxane (b-1) having an epoxy group with a cinnamic acid derivative (b-2) and an aromatic heterocyclic derivative (b-3) containing nitride, oxide or sulfide.
• US5236937A
  申请人：——

  公开号：US5236937A

  公开（公告）日：1993-08-17