(S)-3-methyl-1-hydroxybutan-2-yl benzoate | 1131010-28-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (S)-3-methyl-1-hydroxybutan-2-yl benzoate
• 英文别名: [(2S)-1-hydroxy-3-methylbutan-2-yl] benzoate
• CAS: 1131010-28-0
• 化学式: C₁₂H₁₆O₃
• 分子量: 208.257
• InChiKey: BPYVKVVLQNLBDE-LLVKDONJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  (S)-3-methyl-1-oxobutan-2-yl benzoate 在 sodium tetrahydroborate 作用下， 生成 (S)-3-methyl-1-hydroxybutan-2-yl benzoate
  参考文献：
  名称：

  Organocatalytic α-oxybenzoylation of aldehydes

  摘要：

  A simple method for the asymmetric alpha-oxybenzoylation of aldehydes is presented. Treatment of a series of aldehydes with benzoyl peroxide in the presence of a MacMillan imidazolidinone leads directly to the alpha-oxybenzoylated product with excellent levels of asymmetric induction. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.03.082

文献信息

• Organocatalytic α-oxybenzoylation of aldehydes
  作者：Matti J.P. Vaismaa、Sze Chak Yau、Nicholas C.O. Tomkinson

  DOI：10.1016/j.tetlet.2009.03.082

  日期：2009.7

  A simple method for the asymmetric alpha-oxybenzoylation of aldehydes is presented. Treatment of a series of aldehydes with benzoyl peroxide in the presence of a MacMillan imidazolidinone leads directly to the alpha-oxybenzoylated product with excellent levels of asymmetric induction. (C) 2009 Elsevier Ltd. All rights reserved.
• Kano, Taichi; Mii, Haruka; Maruoka, Keiji, Journal of the American Chemical Society, 2009, vol. 131, p. 3450 - 3451
  作者：Kano, Taichi、Mii, Haruka、Maruoka, Keiji

  DOI：——

  日期：——