(-)-(4S,5S)-1,3-dimethyl-2-(2-((4S,5S)-1,3-dimethyl-4,5-diphenylimidazolidin-2-yl)phenyl)-4,5-diphenylimidazolidine | 891271-45-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: (-)-(4S,5S)-1,3-dimethyl-2-(2-((4S,5S)-1,3-dimethyl-4,5-diphenylimidazolidin-2-yl)phenyl)-4,5-diphenylimidazolidine
• 英文别名: (4S,5S)-2-[2-[(4S,5S)-1,3-dimethyl-4,5-diphenylimidazolidin-2-yl]phenyl]-1,3-dimethyl-4,5-diphenylimidazolidine
• CAS: 891271-45-7
• 化学式: C₄₀H₄₂N₄
• 分子量: 578.8
• InChiKey: RYSGCXXHPMKBFH-ZQWQDMLBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.6
• 重原子数：
  44
• 可旋转键数：
  6
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  13
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (-)-(4S,5S)-1,3-dimethyl-2-(2-((4S,5S)-1,3-dimethyl-4,5-diphenylimidazolidin-2-yl)phenyl)-4,5-diphenylimidazolidine 、 四(3,5-二(三氟甲基)苯基)硼酸钠 在 N-溴代乙酰胺 作用下， 以 乙醚 、 二氯甲烷 、 水 为溶剂， 反应 0.5h， 以80%的产率得到(-)-(4S,5S)-1,3-dimethyl-2-(2-((4S,5S)-1,3-dimethyl-4,5-diphenylimidazolinium-2-yl)phenyl)-4,5-diphenylimidazolinium bis[tetrakis(3,5-bis(trifluoromethyl)phenyl)borate]
  参考文献：
  名称：

  The preparation of new enantiopure imidazolinium salts and their evaluation as catalysts and shift reagents

  摘要：

  A series of new chiral imidazolinium salts were prepared and tested as catalysts. It was possible to show that bis-imidazolinium salts had a higher reactivity than mono-imidazolium salts. In addition a chiral discrimination of the bis-imidazolinium salts with the potassium salt of racemic Mosher's acid wits proven by NMR studies. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2006.02.021
• 作为产物：
  描述：

  (1R,2R)-N,N'-二甲基-1,2-二苯基-1,2-乙二胺 、 邻苯二甲醛 反应 16.0h， 以87%的产率得到(-)-(4S,5S)-1,3-dimethyl-2-(2-((4S,5S)-1,3-dimethyl-4,5-diphenylimidazolidin-2-yl)phenyl)-4,5-diphenylimidazolidine
  参考文献：
  名称：

  The preparation of new enantiopure imidazolinium salts and their evaluation as catalysts and shift reagents

  摘要：

  A series of new chiral imidazolinium salts were prepared and tested as catalysts. It was possible to show that bis-imidazolinium salts had a higher reactivity than mono-imidazolium salts. In addition a chiral discrimination of the bis-imidazolinium salts with the potassium salt of racemic Mosher's acid wits proven by NMR studies. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2006.02.021

文献信息

• The preparation of new enantiopure imidazolinium salts and their evaluation as catalysts and shift reagents
  作者：Václav Jurčík、René Wilhelm

  DOI：10.1016/j.tetasy.2006.02.021

  日期：2006.3

  A series of new chiral imidazolinium salts were prepared and tested as catalysts. It was possible to show that bis-imidazolinium salts had a higher reactivity than mono-imidazolium salts. In addition a chiral discrimination of the bis-imidazolinium salts with the potassium salt of racemic Mosher's acid wits proven by NMR studies. (c) 2006 Elsevier Ltd. All rights reserved.