N-phenyldiethanolamine | 37934-06-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-phenyldiethanolamine
• 英文别名: N-<2-Chlor-aethyl>-N-<2-hydroxy-aethyl>-anilin；N-(2-Chlorethyl)-N-(2-hydroxyethyl)anilin；N-(2-Chlor-aethyl)-N-(2-hydroxy-aethyl)-anilin；2-[N-(2-chloroethyl)anilino]ethanol
• CAS: 37934-06-8
• 化学式: C₁₀H₁₄ClNO
• 分子量: 199.68
• InChiKey: DNEMEPXLMSGQOX-UHFFFAOYSA-N

物化性质

• 沸点：
  168 °C(Press: 2 Torr)
• 密度：
  1.179±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  23.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-phenyldiethanolamine 、 N,N-二甲基甲酰胺 在 三氯氧磷 作用下， 反应 8.5h， 以89%的产率得到4-[双-(2-氯乙基)氨基]苯甲醛
  参考文献：
  名称：

  발색단이 도입된 필터페이퍼를 이용한 수은 이온 검출용 센서 및 그 제조방법

  摘要：

  This invention relates to a sensor for detecting mercury ions using a filter paper with an introduced coloration unit and a method for manufacturing the same, specifically, an organic-inorganic composite sensor for detecting mercury ions immobilized on the surface of the filter paper with fluorescent compounds, and a method for manufacturing the same. According to this invention, by immobilizing fluorescent compounds with excellent selectivity for mercury ions on porous nanomaterial filter paper, the presence of heavy metals such as mercury can be determined by both adsorption and coloration mechanisms.

  公开号：

  KR20150046616A

文献信息

• Processes of preparing asymmetric dinitrobenzamide mustard compounds, intermediate compounds useful therein and products obtained therefrom
  申请人：Atwell Graham John

  公开号：US20100121091A1

  公开（公告）日：2010-05-13

  The invention relates to methods of preparing compounds of formula (II) wherein Z represents —OR 1 or N(R 2 )R 2a —, where R 1 is lower alkylene (C 1 -C 6 ), R 2 is lower alkyl or H and R 2a is lower alkylene (C 1 -C 6 ) or H; Q is absent when R 2a is H and is otherwise selected from the group consisting of H, —OH and protected forms of —OH; one of X and Y is halogen and the other is —OSO 2 R 3 , where R 3 is selected from the group consisting of lower alkyl (C 1 -C 6 ), phenyl and CH 2 phenyl. The method comprises the steps of: (a) reacting a compound of formula (I) with aziridineethanol or a 2-[(2-haloethyl)amino]ethanol in the presence of a metal halide, to form a compound of the formula (III) wherein one of X and E is halogen and the other is hydroxy, and (b) reacting the compound of formula (III) with an alkyl- or arylsulfonyl halide or alkyl- or arylsulfonyl anhydride to obtain a compound of the formula (II). The invention also relates to methods of preparing compounds of formula (IV) from the compounds of formula (II) so obtained, and to novel compounds of formula (IIb) useful as intermediates in these methods.

  本发明涉及制备式（II）化合物的方法，其中Z代表—OR1或N（R2）R2a—，其中R1为低碳链（C1-C6），R2为低碳基或H，R2a为低碳链（C1-C6）或H；当R2a为H时，Q不存在，否则Q选择自羟基（—OH）和保护的羟基形式；X和Y中的一个是卤素，另一个是—OSO2R3，其中R3选择自低碳基（C1-C6）、苯基和CH2苯基。该方法包括以下步骤：（a）在金属卤化物的存在下，将式（I）化合物与环氧丙胺乙醇或2-[(2-卤基乙基)氨基]乙醇反应，形成式（III）化合物，其中X和E中的一个是卤素，另一个是羟基，（b）将式（III）化合物与烷基或芳基磺酰卤或烷基或芳基磺酰酐反应，得到式（II）化合物。本发明还涉及从所得到的式（II）化合物制备式（IV）化合物的方法，以及作为这些方法中间体的新型式（IIb）化合物。
• 발색단이 도입된 필터페이퍼를 이용한 수은 이온 검출용 센서 및 그 제조방법
  申请人：INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY 경상국립대학교산학협력단(220040107194) BRN ▼613-82-11653

  公开号：KR20150046616A

  公开（公告）日：2015-04-30

  본 발명은 발색단이 도입된 필터페이퍼를 이용한 수은 이온 검출용 센서 및 그 제조방법에 관한 것으로, 구체적으로는 형광화합물이 필터페이퍼 표면에 고정화된 수은 이온 검출용 유기-무기 복합 센서 및 그 제조방법에 관한 것이다. 본 발명에 따르면, 수은 이온에 대한 선택성이 우수한 형광화합물을 다공성 나노소재인 필터페이퍼에 고정화함으로써 수은과 같은 중금속을 흡착과 동시에 발색 메커니즘을 통하여 그 존재 여부를 판단할 수 있다.

  This invention relates to a sensor for detecting mercury ions using a filter paper with an introduced coloration unit and a method for manufacturing the same, specifically, an organic-inorganic composite sensor for detecting mercury ions immobilized on the surface of the filter paper with fluorescent compounds, and a method for manufacturing the same. According to this invention, by immobilizing fluorescent compounds with excellent selectivity for mercury ions on porous nanomaterial filter paper, the presence of heavy metals such as mercury can be determined by both adsorption and coloration mechanisms.