2-hydroxy-5-(2-phenyl-2-propyl)-benzaldehyde | 72633-30-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-hydroxy-5-(2-phenyl-2-propyl)-benzaldehyde
• 英文别名: 2-Hydroxy-5-(2-phenylpropan-2-yl)benzaldehyde
• CAS: 72633-30-8
• 化学式: C₁₆H₁₆O₂
• 分子量: 240.302
• InChiKey: AISPDHNUVBHTNV-UHFFFAOYSA-N

物化性质

• 熔点：
  69-70 °C(Solv: ethanol (64-17-5))
• 沸点：
  352.7±27.0 °C(Predicted)
• 密度：
  1.129±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-hydroxy-5-(2-phenyl-2-propyl)-benzaldehyde 在 sodium tetrahydroborate 、 silica gel 作用下， 以 乙醇 、 氯仿 为溶剂， 反应 1.0h， 生成 2-[[3-[[2-Hydroxy-5-(2-phenylpropan-2-yl)phenyl]methylamino]anilino]methyl]-4-(2-phenylpropan-2-yl)phenol
  参考文献：
  名称：

  硼氢化钠-硅胶系统对N,N'-双[5-取代水杨烯]-m/p-苯二胺的简便还原方法

  摘要：

  摘要 一种涉及硼氢化钠/硅胶系统的简单方法提供了一种快速将 N,N'-双[5-取代水杨基] m/p-苯二胺还原成相应胺的方法，收率极佳。在该方法中避免了在一些相关席夫碱的硼氢化物还原中观察到的硼螯合物的形成。

  DOI：

  10.1081/scc-120028641
• 作为产物：
  描述：

  氯仿 、 4-肉桂苯酚 在 sodium hydroxide 作用下， 以 乙醇 、 水 为溶剂， 生成 2-hydroxy-5-(2-phenyl-2-propyl)-benzaldehyde
  参考文献：
  名称：

  Sridharan; Muthusubramanian; Sivasubramanian, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005, vol. 44, # 2, p. 416 - 419

  摘要：

  DOI：

文献信息

• Synthesis and complete NMR characterization of 4-alkyl-2-(6-substituted-1,3-benzoxazol-2-yl)benzenols
  作者：V. Sridharan、S. Muthusubramanian、S. Sivasubramanian

  DOI：10.1002/mrc.1169

  日期：2003.4

  This paper describes the complete assignment of all carbons and hydrogens of several newly synthesized 6-substituted 2-(2-hydroxyaryl)benzoxazoles from 2,2′-dihydroxydiaryl Schiff bases by the use of two-dimensional NMR techniques. Copyright © 2003 John Wiley & Sons, Ltd.

  本文描述了通过二维NMR技术，对几种新合成的6-取代2-(2-羟基芳基)苯并噁唑中所有碳和氢的完全指派，所用起始物为2,2′-二羟基二芳香Schiff碱。版权 © 2003 John Wiley & Sons, Ltd.
• [EN] SALALEN LIGANDS AND ORGANOMETALLIC COMPLEXES<br/>[FR] LIGANDS DE SALALÈNE ET COMPLEXES ORGANOMÉTALLIQUES
  申请人：UNIV RAMOT

  公开号：WO2011158241A1

  公开（公告）日：2011-12-22

  Use of homogeneous catalytic systems which include as a pre-catalyst a complex of a Group IV metal and a salalen ligand in the polymerization of alpha-olefins, is disclosed. The alpha-olefin polymers obtained are characterized by controlled levels of tacticity. Also disclosed are novel salalen ligands and novel complexes thereof with Group IV metals.

  本发明揭示了在α-烯烃聚合中使用包括群四金属和Salalen配体复合物作为前催化剂的均相催化体系。所得的α-烯烃聚合物具有受控的立构度水平。还公开了新型Salalen配体以及与群四金属形成的新型配合物。
• NMR investigation of hydrogen bonding and 1,3-tautomerism in 2-(2-hydroxy-5-substituted-aryl) benzimidazoles
  作者：V. Sridharan、S. Saravanan、S. Muthusubramanian、S. Sivasubramanian

  DOI：10.1002/mrc.1588

  日期：2005.7

  1,3‐tautomerism associated with 2‐(2‐hydroxy‐5‐substituted‐aryl)benzimidazoles was studied in different solvents. The effect of hydrogen bonding involving the hydroxyl group of the 2‐aryl ring on the tautomerism was investigated using NMR spectroscopy. The influence of the solvent concentration on 2‐(2‐hydroxy‐5‐chloroaryl)benzimidazole was studied in acetone‐d6 and DMSO‐d6. Copyright © 2005 John Wiley

  在不同溶剂中研究了与 2-(2-羟基-5-取代的芳基)苯并咪唑相关的 1,3-互变异构现象。使用NMR光谱研究了涉及2-芳环羟基的氢键对互变异构的影响。在丙酮-d6和DMSO-d6中研究了溶剂浓度对2-(2-羟基-5-氯芳基)苯并咪唑的影响。版权所有 © 2005 John Wiley & Sons, Ltd.
• METAL COMPLEXES OF SALAN-TYPE LIGANDS AND USES THEREOF AS CATALYSTS FOR POLYMERIZATION OF ALPHA-OLEFINS
  申请人：Kol Moshe

  公开号：US20130310529A1

  公开（公告）日：2013-11-21

  Use of homogeneous catalytic systems which include as a pre-catalyst a complex of a group 4 metal and a Salan ligand in the polymerization of alpha-olefins, is disclosed. The Salan ligand is characterized by a sequential diamino-containing skeleton unit which is non-symmetric, and the pre-catalysts can also be such that are devoid of a symmetry element. The disclosed polymerization results in alpha-olefin polymers such as polypropylene which are characterized by high levels of tacticity. Also disclosed are novel Salan ligands and novel complexes thereof with group 4 metals.

  揭示了在α-烯烃聚合中使用包括第4族金属和Salan配体的预催化剂的均相催化体系的用途。Salan配体的特点是具有非对称的顺序二氨基骨架单元，预催化剂也可以是不具有对称元素的。所揭示的聚合产物为α-烯烃聚合物，例如高度具有定向性的聚丙烯。还揭示了新型的Salan配体及其与第4族金属的新配合物。
• SALALEN LIGANDS AND ORGANOMETALLIC COMPLEXES
  申请人：Kol Moshe

  公开号：US20130096271A1

  公开（公告）日：2013-04-18

  Use of homogeneous catalytic systems which include as a pre-catalyst a complex of a Group IV metal and a salalen ligand in the polymerization of alpha-olefins, is disclosed. The alpha-olefin polymers obtained are characterized by controlled levels of tacticity. Also disclosed are novel salalen ligands and novel complexes thereof with Group IV metals.

  揭示了在α-烯烃聚合中使用包括一种Group IV金属和一种salalen配体的前催化剂的均相催化系统。所获得的α-烯烃聚合物具有可控的立构性水平。还揭示了新型的salalen配体及其与Group IV金属的新型配合物。