fluoren-9-ylidene-malonic acid dimethyl ester | 119292-75-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: fluoren-9-ylidene-malonic acid dimethyl ester
• 英文别名: Fluoren-9-yliden-malonsaeure-dimethylester；9-Fluorenyliden-malonsaeure-dimethylester；Dimethyl 2-fluoren-9-ylidenepropanedioate；dimethyl 2-fluoren-9-ylidenepropanedioate
• CAS: 119292-75-0
• 化学式: C₁₈H₁₄O₄
• 分子量: 294.307
• InChiKey: VADAKAXXPZNILS-UHFFFAOYSA-N

物化性质

• 沸点：
  410.8±40.0 °C(Predicted)
• 密度：
  1.278±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  9,9-二氯芴 、 alkaline earth salt of/the/ methylsulfuric acid 生成 fluoren-9-ylidene-malonic acid dimethyl ester
  参考文献：
  名称：

  Mediation of flowering by a calmodulin-dependent protein kinase

  摘要：

  A calmodulin-dependent protein kinase (MCK1) appeared important in regulating flowering in tobacco. The expression of modified MCK1 that lacks the C-terminal including calmodulin-binding domain upsets the flowering developmental program, leading to the abortion of flower primordia initiated on the main axis of the plant and, as well, caused the prolongation of the vegetative phase in axillary buds. The abortion process of flowers began first in the developing anthers and subsequently the entire flower senesces. In axillary buds the prolonged vegetative phase was characterized by atypical elongated, narrow, twisted leaves. These results suggested a role for calmodulin-dependent protein kinase homologs in mediating flowering.

  DOI：

  10.1007/bf02882393

文献信息

• COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES
  申请人：HALLSTAR INNOVATIONS CORP.

  公开号：US20140044654A1

  公开（公告）日：2014-02-13

  The present disclosure relates, according to some embodiments, to molecules, including conjugated fused polycyclic molecules, that may receive excited state energy from other molecules (e.g., light-absorbing molecules) or directly from the irradiation sources. According to some embodiments, the disclosure relates to molecules, including conjugated fused polycyclic molecules, that may resolve (e.g., quench, dissipate) excited state energy, normally by way of releasing it as heat. (e.g., as heat). Conjugated fused polycyclic molecules of various structures are disclosed including Formula III: The disclosure further relates to methods of use and/or therapy using molecules of Formulas I, II, and/or III.

  本公开涉及一些实施例，涉及分子，包括共轭融合多环分子，这些分子可以从其他分子（例如吸收光的分子）或直接从辐射源接收激发态能量。根据一些实施例，本公开涉及分子，包括共轭融合多环分子，这些分子可以通过释放为热量的方式解决（例如，熄灭，耗散）激发态能量。披露了具有各种结构的共轭融合多环分子，包括式III。本公开还涉及使用式I、II和/或III的分子进行治疗和/或疗法的方法。
• Method of quenching singlet and triplet excited states of photodegradable pigments, such as porphyrin compounds, particularly protoporphyrin IX, with conjugated fused tricyclic compounds having electron withdrawing groups, to reduce generation of singlet oxygen
  申请人：Hallstar Innovations Corp.

  公开号：US10632096B2

  公开（公告）日：2020-04-28

  A method of quenching excited state energy from a photodegradable pigment that has been excited by absorption of light having a wavelength in the wavelength range of 290-800 nm, comprising reacting a pigment with a conjugated fused tricyclic compound having electron withdrawing groups of Formula (II) or a salt thereof: wherein: A is selected from the group consisting of O, S, C═O, C═S, B1, B2, D1 and D2 are each independently selected from the group consisting of F, Cl, Br, I, CF3, CC13, NR33+, NO2, CN, C(═O)R4, C(═O)OR′, SO2R5, aryl, and —C═CHR6; each m independently is 0, 1, 2, 3, or 4; a is 0 or 1; each R′ is independently selected from the group consisting of LI, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, and aryl; R2 is selected from the group consisting of H, alkyl, cycloalkyl, alkenyl, alkynyl, and aryl; each R3 is independently selected from the group consisting of H and C1-C6 alkyl; each R4 is independently selected from the group consisting of H, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, and aryl; each R5 is independently selected from the group consisting of H, O, OH, NH2, and Cl; and each R6 is-independently selected from the group consisting of alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, and aryl.

  一种淬灭光降解颜料激发态能量的方法，该颜料通过吸收波长在 290-800 纳米范围内的光而激发，该方法包括使颜料与具有式 (II) 或其盐类电子萃取基团的共轭熔融三环化合物反应： 其中： A 选自 O、S、C═O、C═S 所组成的组、 B1、B2、D1 和 D2 各自独立地选自由 F、Cl、Br、I、CF3、CC13、NR33+、NO2、CN、C(═O)R4、C(═O)OR′、SO2R5、芳基和-C═CHR6 组成的组； 每个 m 独立地为 0、1、2、3 或 4； a 是 0 或 1； 每个 R′独立地选自由 LI、烷基、烯基、炔基、环烷基、环烯基和芳基组成的组； R2 选自由 H、烷基、环烷基、烯基、炔基和芳基组成的组； 每个 R3 独立选自由 H 和 C1-C6 烷基组成的组 每个 R4 独立地选自由 H、烷基、烯基、炔基、环烷基、环烯基和芳基组成的组； 每个 R5 独立地选自由 H、O、OH、NH2 和 Cl 组成的组；以及 每个 R6 独立地选自由烷基、烯基、炔基、环烷基、环烯基和芳基组成的组。
• Koebrich,G. et al., Chemische Berichte, 1968, vol. 101, p. 2644 - 2659
  作者：Koebrich,G. et al.

  DOI：——

  日期：——
• METHOD OF QUENCHING SINGLET AND TRIPLET EXCITED STATES OF PIGMENTS, SUCH AS PORPHYRIN COMPOUNDS, PARTICULARLY PROTOPORPHYRIN IX, WITH CONJUGATED FUSED TRICYCLIC COMPOUNDS HAVE ELECTRON WITHDRAWING GROUPS, TO REDUCE GENERATION OF REACTIVE OXYGEN SPECIES, PARTICULARLY SINGLET OXYGEN
  申请人：HALLSTAR INNOVATIONS CORP.

  公开号：US20150164852A1

  公开（公告）日：2015-06-18

  A method of quenching excited state energy from a pigment that has been excited by absorption of light having a wavelength in the wavelength range of 290-800 nm, comprising reacting a pigment with a conjugated fused tricyclic compound having electron withdrawing groups: of Formula (II) or a salt thereof: wherein: A is selected from the group consisting of O, S, C═O, C═S, and B 1 , B 2 , D 1 , and D 2 are each independently selected from the group consisting of F, Cl, Br, I, CF 3 , CCl 3 , NR 3 3 + , NO 2 , CN, C(═O)R 4 , C(═O)OR 1 , SO 2 R 5 , aryl, and —C═CHR 6 ; each m independently is 0, 1, 2, 3, or 4; n is 0 or 1; each R 1 is independently selected from the group consisting of H, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, and aryl; R 2 is selected from the group consisting of H, alkyl, cycloalkyl, alkenyl, alkynyl, and aryl; each R 3 is independently selected from the group consisting of H and C 1 -C 6 alkyl; each R 4 is independently selected from the group consisting of H, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, and aryl; each R 5 is independently selected from the group consisting of H, O − , OH, NH 2 , and Cl; and, each R 6 is independently selected from the group consisting of alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, and aryl.
• US9145383B2
  申请人：——

  公开号：US9145383B2

  公开（公告）日：2015-09-29