4-(biphenyl-4-yl)-1-(3-chlorophenyl)-1H-1,2,3-triazole | 1599471-89-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(biphenyl-4-yl)-1-(3-chlorophenyl)-1H-1,2,3-triazole
• 英文别名: 1-(3-Chlorophenyl)-4-(4-phenylphenyl)triazole；1-(3-chlorophenyl)-4-(4-phenylphenyl)triazole
• CAS: 1599471-89-2
• 化学式: C₂₀H₁₄ClN₃
• 分子量: 331.804
• InChiKey: XXAYJYFAALWGLX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  30.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-氯苯胺 在 盐酸 、 sodium nitrite 作用下， 以 水 为溶剂， 反应 7.13h， 生成 4-(biphenyl-4-yl)-1-(3-chlorophenyl)-1H-1,2,3-triazole
  参考文献：
  名称：

  Cu(II)-anchored functionalized mesoporous SBA-15: An efficient and recyclable catalyst for the one-pot Click reaction in water

  摘要：

  A new pyridine-imine functionalized mesoporus silica (SBA-15) has been synthesized through the Schiff-base condensation of 3-aminopropyl functionalized SBA-15 with 2-pyridinecarboxaldehyde followed by the grafting of Cu(II) onto it resulting a new Cu@Pylm-SBA-15 material. 20-hexagonally ordered mesophases of the material are analyzed by small-angle powder X-ray diffractions (PXRD) and transmission electron microscopic (TEM) image analyses. The Cu(ll)-anchored mesoporous material, Cu@PyIm-SBA-15 showed excellent catalytic activity towards the one pot click reaction between azides formed in situ from the corresponding amines and acetylenes in water at 0 C to room temperature resulting a wide variety of 1,4-disubstituted 1,2,3-triazoles. The catalyst has been recycled for five cycles without any appreciable loss of catalytic activity and also without any appreciable Cu-leaching, suggesting a future potential of this novel mesoporous catalyst for the synthesis of 1,4-disubstituted 1,2,3-triazoles. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molcata.2014.01.027

文献信息

• Cu(II)-anchored functionalized mesoporous SBA-15: An efficient and recyclable catalyst for the one-pot Click reaction in water
  作者：Susmita Roy、Tanmay Chatterjee、Malay Pramanik、Anupam Singha Roy、Asim Bhaumik、Sk. Manirul Islam

  DOI：10.1016/j.molcata.2014.01.027

  日期：2014.5

  A new pyridine-imine functionalized mesoporus silica (SBA-15) has been synthesized through the Schiff-base condensation of 3-aminopropyl functionalized SBA-15 with 2-pyridinecarboxaldehyde followed by the grafting of Cu(II) onto it resulting a new Cu@Pylm-SBA-15 material. 20-hexagonally ordered mesophases of the material are analyzed by small-angle powder X-ray diffractions (PXRD) and transmission electron microscopic (TEM) image analyses. The Cu(ll)-anchored mesoporous material, Cu@PyIm-SBA-15 showed excellent catalytic activity towards the one pot click reaction between azides formed in situ from the corresponding amines and acetylenes in water at 0 C to room temperature resulting a wide variety of 1,4-disubstituted 1,2,3-triazoles. The catalyst has been recycled for five cycles without any appreciable loss of catalytic activity and also without any appreciable Cu-leaching, suggesting a future potential of this novel mesoporous catalyst for the synthesis of 1,4-disubstituted 1,2,3-triazoles. (C) 2014 Elsevier B.V. All rights reserved.