bis-(1-phenyl-cyclopentyl)-ketone | 15811-02-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: bis-(1-phenyl-cyclopentyl)-ketone
• 英文别名: Bis-(1-phenyl-cyclopentyl)-keton；Di-(1-phenyl-cyclopent-1-yl)-keton；Bis(1-phenylcyclopentyl)methanone
• CAS: 15811-02-6
• 化学式: C₂₃H₂₆O
• 分子量: 318.459
• InChiKey: CDPVSMOWSSCGOX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-苯基环戊烷羧酸 在 sodium 、 甲苯 作用下， 生成 bis-(1-phenyl-cyclopentyl)-ketone
  参考文献：
  名称：

  The Acyloin Condensation of Aralkyl Esters

  摘要：

  DOI：

  10.1021/ja01139a038

文献信息

• METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE
  申请人：Yeo Wee Chuan

  公开号：US20100179343A1

  公开（公告）日：2010-07-15

  The present invention relates to a method of producing an optically active cyanohydrin derivative, which comprises reacting an aldehyde or an asymmetrical ketone with a cyanating agent in the presence of a Lewis base and a titanium compound produced from a partial hydrolysate of titanium tetraalkoxide and an optically active ligand represented by formula (II) or a titanium oxoalkoxide compound represented by formula (I) [Ti x O y ](OR 1 ) 4x-2y , and an optically active ligand represented by formula (II), wherein R 1 is an optionally substituted alkyl group or an optionally substituted aryl group; x is an integer of not less than 2; y is an integer of not less than 1; and y/x satisfies 0.1

  本发明涉及一种制备光学活性氰醇衍生物的方法，包括在Lewis碱和由钛四烷氧化物的部分水解物和式(I)[TixOy](OR1)4x-2y，以及由式(II)表示的光学活性配体组成的钛氧烷衍生物的存在下，将醛或不对称酮与氰化试剂反应。其中，R1是可选的取代基的烷基或芳基；x为不小于2的整数；y为不小于1的整数；且y/x满足0.1
• TITANIUM COMPOUND AND METHOD FOR PRODUCING OPTICALLY ACTIVE CYANOHYDRINS
  申请人：Mitsui Chemicals, Inc.

  公开号：EP1806336B1

  公开（公告）日：2009-09-30
• Mazaleyrat,J.-P., Canadian Journal of Chemistry, 1978, vol. 56, p. 2731 - 2736
  作者：Mazaleyrat,J.-P.

  DOI：——

  日期：——
• Titanium Compound and Process for Producing Optically Active Cyanohydrins
  申请人：Yoshinaga Kazuhiko

  公开号：US20070265463A1

  公开（公告）日：2007-11-15

  The present invention relates to a titanium compound produced from a reaction mixture of a titanium tetraalkoxide compound with water and an optically active ligand represented by the following general formula (1), or a titanium oxoalkoxide compound and an optically active ligand represented by the following general formula (1), wherein, in the formula, R 2 , R 3 and R 4 independently represent a hydrogen atom, an alkyl group or the like, and A* represents a hydrocarbon-containing group with three or more carbon atoms having an asymmetric carbon atom or axial asymmetry. The invention further relates to a process for producing optically active cyanohydrins which is characterized by reacting a carbonyl compound with a cyanating agent in the presence of such a titanium compound.
• US6013836A
  申请人：——

  公开号：US6013836A

  公开（公告）日：2000-01-11