2,3,4,5,6-Pentamethyl-benzhydrol | 24255-57-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,3,4,5,6-Pentamethyl-benzhydrol
• 英文别名: (+/-)-Hydroxy-phenyl-(pentamethyl-phenyl)-methan；(+/-)-Phenyl-(pentamethyl-phenyl)-methanol；(α-Hydroxy-benzyl)-pentamethylbenzol；(2,3,4,5,6-Pentamethylphenyl)-phenylmethanol
• CAS: 24255-57-0
• 化学式: C₁₈H₂₂O
• 分子量: 254.372
• InChiKey: JTSXBBDWXPSBQM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2,3,4,5,6-五甲基苯甲酮 在 lithium aluminium tetrahydride 作用下， 生成 2,3,4,5,6-Pentamethyl-benzhydrol
  参考文献：
  名称：

  Preparation and Properties of Substituted Benzhydryl Carbonium Ions

  摘要：

  DOI：

  10.1021/ja01612a018

文献信息

• Clement, Annales de Chimie (Cachan, France), 1940, vol. <11> 13, p. 243,302
  作者：Clement

  DOI：——

  日期：——
• IFEMS: A new approach for monitoring wildfire evolution with NOAA-AVHRR imagery
  作者：K. R. Al-Rawi、J. L. Casanova、A. Romo

  DOI：10.1080/01431160119349

  日期：2001.1

  A new approach for monitoring wildfire evolution was developed. It was achieved by integrating both the burned area mapping system and the fire detection system. Multi-spectral multi-temporal images of the National Oceanic and Atmospheric Administration Advanced Very High Resolution Radiometer (NOAA-AVHRR) were employed. The new system has an excellent performance in monitoring fire growth due to its ability of capturing areas that were burned completely between two consecutive images, as well as those which were burned before the monitoring time. In addition, the system has the ability to differentiate among burned areas, active fire (fire front) and the area beneath flames. The algorithm of the system is described. The false alarm due to the saturation problem of channel 3 was avoided. The integration of the system with fire simulation programs for fire monitoring is discussed.
• MOLECULAR INHIBITORS OF THE WNT/BETA-CATENIN PATHWAY
  申请人：Moon Randall T.

  公开号：US20120040916A1

  公开（公告）日：2012-02-16

  The present invention is directed toward a method of treating a subject for a condition mediated by the Wnt/β-catenin pathway by selecting a subject with a condition mediated by the Wnt/β-catenin pathway and administering to the selected subject a compound selected from the group consisting of those set forth in Table 1, Table 2, and a pharmaceutically acceptable salt thereof. A method of similarly inhibiting the Wnt/β-catenin pathway in a subject is also disclosed.