N.N-Dimethyl-2-aethyl-but-1-enyl-amin | 16792-75-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N.N-Dimethyl-2-aethyl-but-1-enyl-amin
• 英文别名: cyclohexylidene-N,N-dimethylmethanamine；1-cyclohexylidene-N,N-dimethylmethanamine
• CAS: 16792-75-9
• 化学式: C₉H₁₇N
• 分子量: 139.241
• InChiKey: JGLWGMLJXMJSSH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N.N-Dimethyl-2-aethyl-but-1-enyl-amin 、 马来酸二乙酯 生成 1-Dimethylamino-2,3-di(ethoxycarbonyl)-spiro<3.5>nonan
  参考文献：
  名称：

  Enamine Chemistry. IV. Cycloaddition Reactions of Enamines Derived from Aldehydes and Acyclic Ketones^1,2

  摘要：

  DOI：

  10.1021/jo01027a009
• 作为产物：
  描述：

  N,N-二甲基环己烷羧酰胺 在 dihydrogen hexachloroplatinate(IV) hexahydrate 、 1,1,3,3-四甲基二硅氧烷 作用下， 以 四氢呋喃 、 甲苯 为溶剂， 反应 5.0h， 以70%的产率得到N,N-二甲基环己基甲基胺
  参考文献：
  名称：

  Practical Access to Amines by Platinum-Catalyzed Reduction of Carboxamides with Hydrosilanes: Synergy of Dual Si−H Groups Leads to High Efficiency and Selectivity

  摘要：

  The synergetic effect of two Si-H groups leads to efficient reduction of carboxamides to amines by platinum catalysts under mild conditions The rate of the reaction is dependent on the distance of two Si-H groups, 1,1,3,3-tetramethyidisiloxane (TMDS) and 1,2-bis(dimethylsilyl)benzene are found to be an effective reducing reagent. The reduction of amides having other reducible functional groups such as NO2, CO2R, CN, C=C, Cl, and Br moieties proceeds with these groups remaining intact, providing a reliable method for the access to functionalized amine derivatives. The platinum-catalyzed reduction of amides with polymethylhydrosiloxane (PMHS) also proceeds under mild conditions. The reaction is accompanied by automatic removal of both platinum and silicon wastes as insoluble silicone resin, and the product is obtained by simple extraction. A mechanism involving double oxidative addition of TMDS to a platinum center is discussed.

  DOI：

  10.1021/ja9055307

文献信息

• 2-(Pyridin-2-yl)-pyrimidines and Their Use for Controlling Harmful Fungi
  申请人：Grammenos Wassilios

  公开号：US20100286175A1

  公开（公告）日：2010-11-11

  The invention relates to 2-(pyridin-2-yl)-pyrimidine compounds of general formula (I) and their use for controlling pathogenic fungi and as plant protection products that, as an active constituent, contain compounds of this type: In general formula (I), k represents 0, 1, 2, 3; m represents 0, 1, 2, 3, 4 or 5; n represents 1, 2, 3, 4 or 5; R 1 , independent of one another, represents halogen, OH, CN, NO 2 , C 1 -C 4 alkyl, C 1 -C 4 alkyl halide, C 1 -C 4 alkoxy, C 1 -C 4 alkoxy halide, C 2 -C 4 alkenyl, C 2 -C 4 alkynyl, C 3 -C 8 cycloalkyl, C 1 -C 4 alkoxy-C 1 -C 4 alkyl, amino, phenoxy, which is optionally substituted by halogen or C 1 -C 4 alkyl, NHR, NR 2 , C(R a )═N—OR b , S(═O) p A 1 or C(═O)A 2 , or two radicals R 1 bound to adjacent carbon atoms can, together, also represent a group —O-Alk-O—, wherein Alk represents a linear or branched C 1 -C 4 alkylene, and 1, 2, 3 or 4 hydrogen atoms can also be replaced by halogen; R 2 represents C 1 -C 4 alkyl halide, C 1 -C 4 alkoxy, C 1 -C 4 alkoxy halide, hydroxy, halogen, CN or NO 2 ; whereby R 2 can also represent hydrogen or C 1 -C 4 alkyl when at least one of the three following conditions is fulfilled: n represents 3, 4 or 5; k represents 1, 2 or 3; if m is not equal to 0, at least one of the radicals R 1 represents a radical that differs from halogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy and C 1 -C 4 alkyl halide, and; R 3 represents C 1 -C 4 alkyl.

  本发明涉及一般式（I）的2-(吡啶-2-基)-嘧啶化合物及其用于控制病原真菌和作为植物保护产品的用途，作为活性成分含有此类化合物：在一般式（I）中，k表示0、1、2或3；m表示0、1、2、3、4或5；n表示1、2、3、4或5；R1独立地表示卤素、OH、CN、NO2、C1-C4烷基、C1-C4烷基卤素、C1-C4烷氧基、C1-C4烷氧基卤素、C2-C4烯基、C2-C4炔基、C3-C8环烷基、C1-C4烷氧基-C1-C4烷基、氨基、苯氧基，该苯氧基可选择地被卤素或C1-C4烷基取代、NHR、NR2、C(Ra)═N—ORb、S(═O)pA1或C(═O)A2，或者相邻碳原子上结合的两个基R1也可以表示一个基团—O-Alk-O—，其中Alk表示直链或支链的C1-C4烷基，1、2、3或4个氢原子也可以被卤素取代；R2表示C1-C4烷基卤素、C1-C4烷氧基、C1-C4烷氧基卤素、羟基、卤素、CN或 ；当满足以下至少三个条件之一时，R2也可以表示氢或C1-C4烷基：n表示3、4或5；k表示1、2或3；如果m不等于0，则至少一个基团R1表示与卤素、C1-C4烷基、C1-C4烷氧基和C1-C4烷基卤素不同的基团；R3表示C1-C4烷基。
• Preparation of enamines by addition of Grignard reagents to N,N-dialkylformamides
  作者：Christer Hansson、Borje Wickberg

  DOI：10.1021/jo00957a044

  日期：1973.8
• DYONG I.; LAM-CHI Q., ANGEW. CHEM., 1979, 91, NO 12, 997-998
  作者：DYONG I.、 LAM-CHI Q.

  DOI：——

  日期：——