(5S,6S)-6-((E)-2-{(2R,4R,5R)-5-allyl-2-(4-{[tert-butyl(dimethyl)silyl]oxy}phenyl)-4-[2-(trityloxy)ethyl]-[1,3]dioxolan-4-yl}vinyl)-5-ethyl-5,6-dihydro-2H-pyran-2-one | 521274-29-3

分子结构分类

有机化合物 - 苯类化合物 - 三苯基化合物

中文名称

——

中文别名

——

英文名称

(5S,6S)-6-((E)-2-{(2R,4R,5R)-5-allyl-2-(4-{[tert-butyl(dimethyl)silyl]oxy}phenyl)-4-[2-(trityloxy)ethyl]-[1,3]dioxolan-4-yl}vinyl)-5-ethyl-5,6-dihydro-2H-pyran-2-one

英文别名

(2S,3S)-2-[(E)-2-[(2R,4R,5R)-2-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-5-prop-2-enyl-4-(2-trityloxyethyl)-1,3-dioxolan-4-yl]ethenyl]-3-ethyl-2,3-dihydropyran-6-one

(5S,6S)-6-((E)-2-{(2R,4R,5R)-5-allyl-2-(4-{[tert-butyl(dimethyl)silyl]oxy}phenyl)-4-[2-(trityloxy)ethyl]-[1,3]dioxolan-4-yl}vinyl)-5-ethyl-5,6-dihydro-2H-pyran-2-one化学式

CAS

521274-29-3

化学式

C₄₈H₅₆O₆Si

mdl

——

分子量

757.055

InChiKey

GHKFGYQQCKCOAK-BKAMAKSHSA-N

BEILSTEIN

——

EINECS

——

物化性质

沸点：

771.2±60.0 °C(Predicted)
密度：

1?+-.0.06 g/cm3(Predicted)

计算性质

辛醇/水分配系数(LogP)：

11.26
重原子数：

55
可旋转键数：

16
环数：

6.0
sp3杂化的碳原子比例：

0.35
拓扑面积：

63.2
氢给体数：

0
氢受体数：

6

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	ethyl (2Z,4S,5S,6E)-7-{(2R,4R,5R)-5-allyl-2-(4-{[tert-butyl(dimethyl)silyl]oxy}phenyl)-4-[2-(tritylioxy)ethyl]-[1,3]dioxolan-4-yl}-4-ethyl-5-hydroxyhepta-2,6-dienoate	521274-28-2	C₅₀H₆₂O₇Si	803.124
——	(2E)-3-{(2R,4R,5R)-5-allyl-2-(4-{[tert-butyl(dimethyl)silyl]oxy}phenyl)-4-[2-(trityloxy)ethyl]-[1,3]dioxolan-4-yl}acrylaldehyde	521274-26-0	C₄₂H₄₈O₅Si	660.926
——	(R)-3-{(E)-(2R,3S)-5-[(2R,4R,5R)-5-Allyl-2-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-4-(2-trityloxy-ethyl)-[1,3]dioxolan-4-yl]-2-ethyl-3-hydroxy-pent-4-enoyl}-4-benzyl-oxazolidin-2-one	521274-27-1	C₅₆H₆₅NO₈Si	908.22
——	(4R)-4-benzyl-3-[(E,2R,3S)-5-[(2R,4R,5R)-2-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-5-prop-2-enyl-4-(2-trityloxyethyl)-1,3-dioxolan-4-yl]-2-ethyl-3-triethylsilyloxypent-4-enoyl]-1,3-oxazolidin-2-one	1053731-78-4	C₆₂H₇₉NO₈Si₂	1022.48
——	(4R,5R,6E)-8-tri(propan-2-yl)silyloxy-5-(2-trityloxyethyl)octa-1,6-diene-4,5-diol	521274-24-8	C₃₈H₅₂O₄Si	600.914

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	2-[(2R,4R,5R)-2-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-5-[(E)-2-[(2S,3S)-3-ethyl-6-oxo-2,3-dihydropyran-2-yl]ethenyl]-5-(2-trityloxyethyl)-1,3-dioxolan-4-yl]acetaldehyde	521274-30-6	C₄₇H₅₄O₇Si	759.027
——	(5S,6S)-6-{(E)-2-[(2R,4R,5R)-2-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-5-{(3Z,5Z)-(R)-2-hydroxy-6-[(1R,3S)-3-(4-methoxy-phenoxymethoxy)-cyclohexyl]-hexa-3,5-dienyl}-4-(2-trityloxy-ethyl)-[1,3]dioxolan-4-yl]-vinyl}-5-ethyl-5,6-dihydro-pyran-2-one	521274-33-9	C₆₅H₇₈O₁₀Si	1047.41
——	(5S,6S)-6-((E)-2-{(2R,4R,5R)-2-(4-{[tert-butyl(dimethyl)silyl]oxy}phenyl)-5-((2R,5Z)-2-hydroxy-6-{(1R,3S)-3-[(4-methoxyphenoxy)methoxy]cyclohexyl}hex-5-en-3-ynyl)-4-[2-(trityloxy)ethyl]-[1,3]dioxolan-4-yl}vinyl)-5-ethyl-5,6-dihydro-2H-pyran-2-one	521274-32-8	C₆₅H₇₆O₁₀Si	1045.4
——	[(2R,3Z,5Z)-1-[(2R,4R,5R)-2-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-5-[(E)-2-[(2S,3S)-3-ethyl-6-oxo-2,3-dihydropyran-2-yl]ethenyl]-5-(2-trityloxyethyl)-1,3-dioxolan-4-yl]-6-[(1R,3S)-3-[(4-methoxyphenoxy)methoxy]cyclohexyl]hexa-3,5-dien-2-yl] 2-phenoxyacetate	521274-34-0	C₇₃H₈₄O₁₂Si	1181.55
——	[(2R,3Z,5Z)-1-[(2R,4R,5R)-5-(2-azidoethyl)-2-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-5-[(E)-2-[(2S,3S)-3-ethyl-6-oxo-2,3-dihydropyran-2-yl]ethenyl]-1,3-dioxolan-4-yl]-6-[(1R,3S)-3-[(4-methoxyphenoxy)methoxy]cyclohexyl]hexa-3,5-dien-2-yl] 2-phenoxyacetate	521274-44-2	C₅₄H₆₉N₃O₁₁Si	964.241
——	(1R,2Z,4Z)-1-{(2R,3R,4E)-3-(2-{[(allyloxyl)carbonyl]amino}ethyl)-5-[(2S,3S)-3-ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]-2,3-dihydroxypent-4-enyl}-5-{(1R,3S)-3-[(4-methoxyphenoxy)methyl]cyclohexyl}penta-2,4-dienyl phenoxyacetate	521274-36-2	C₄₅H₅₇NO₁₂	803.947
——	[(1S,3R)-3-[(1Z,3Z,5R,7R,8R,9E)-7-bis(prop-2-enoxy)phosphoryloxy-10-[(2S,3S)-3-ethyl-6-oxo-2,3-dihydropyran-2-yl]-5-(2-phenoxyacetyl)oxy-8-[2-(prop-2-enoxycarbonylamino)ethyl]-8-trimethylsilyloxydeca-1,3,9-trienyl]cyclohexyl] (6S)-6-methyloctanoate	521274-37-3	C₅₅H₈₂NO₁₄PSi	1040.31

反应信息

作为反应物：

描述：

(5S,6S)-6-((E)-2-{(2R,4R,5R)-5-allyl-2-(4-{[tert-butyl(dimethyl)silyl]oxy}phenyl)-4-[2-