2-<(E)-hex-1'-enyl>tetrahydropyran-3-one | 155627-43-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: 2-<(E)-hex-1'-enyl>tetrahydropyran-3-one
• 英文别名: 2-(E)-hex-1'-enyltetrahydropyran-3-one；2-[(E)-hex-1-enyl]oxan-3-one
• CAS: 155627-43-3
• 化学式: C₁₁H₁₈O₂
• 分子量: 182.263
• InChiKey: NGPUPTIFATUCHF-VMPITWQZSA-N

物化性质

• 沸点：
  269.6±40.0 °C(Predicted)
• 密度：
  1.015±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-<(E)-hex-1'-enyl>tetrahydropyran-3-one 在 sodium tetrahydroborate 、 对甲苯磺酰肼 作用下， 生成 (E)-2-(1-hexenyl)tetrahydro-2H-pyran
  参考文献：
  名称：

  Synthesis of 2-[(E)-Hex-1′-enyl]tetrahydropyran Starting from 3-Nitro-4,5-dihydro-6H-pyran

  摘要：

  The four steps preparation of 2-[(E)-hex-1'-enyl]tetrahydropyran starting from 3-nitro-4,5-dihydro-6H-pyran has been carried out in 40% overall yield.

  DOI：

  10.1080/00397919708006087
• 作为产物：
  描述：

  2-((E)-Hex-1-enyl)-3-nitro-tetrahydro-pyran 在 ammonium cerium(IV) nitrate 、 lithium sulfide 作用下， 以 乙腈 为溶剂， 反应 52.5h， 生成 2-<(E)-hex-1'-enyl>tetrahydropyran-3-one
  参考文献：
  名称：

  Synthesis of 2-[(E)-Hex-1′-enyl]tetrahydropyran Starting from 3-Nitro-4,5-dihydro-6H-pyran

  摘要：

  The four steps preparation of 2-[(E)-hex-1'-enyl]tetrahydropyran starting from 3-nitro-4,5-dihydro-6H-pyran has been carried out in 40% overall yield.

  DOI：

  10.1080/00397919708006087

文献信息

• Reactivity of 3-nitro-5,6-dihydro-4H-pyran with organoalanes: Preparation of (E)-α, β-ethylenic aldehydes.
  作者：Rita Menicagli、Vito Guagnano、Corrado Malanga

  DOI：10.1016/s0040-4020(01)80858-9

  日期：1994.1

  3-Nitro-5,6-dihydro-4H-pyran reacts with organoalanes and gives 1, 4 addition products. In suitable hydrolysis conditions, the reaction results in the formation of aldehydes that are C-1-homologues of the chain transferred by the alane.
• Menicagli Rita, Guagnano Vito, Malanga Corrado, Tetrahedron, 50 (1994) N 6, S 1871-1876
  作者：Menicagli Rita, Guagnano Vito, Malanga Corrado

  DOI：——

  日期：——
• Synthesis of 2-[(E)-Hex-1′-enyl]tetrahydropyran Starting from 3-Nitro-4,5-dihydro-6H-pyran
  作者：Federica Balzano、Corrado Malanga、Rita Menicagli

  DOI：10.1080/00397919708006087

  日期：1997.5

  The four steps preparation of 2-[(E)-hex-1'-enyl]tetrahydropyran starting from 3-nitro-4,5-dihydro-6H-pyran has been carried out in 40% overall yield.