5H-furo[3,2-c]pyridine-4-thione | 33007-10-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 呋喃吡啶类
• 英文名称: 5H-furo[3,2-c]pyridine-4-thione
• 英文别名: Thioxo-4 dihydro-4,5 furo<3,2-c>pyridin；Furo[3,2-c]pyridine-4(5H)-thione；5H-furo[3,2-c]pyridine-4-thione
• CAS: 33007-10-2
• 化学式: C₇H₅NOS
• 分子量: 151.189
• InChiKey: LPRVEGMDCBFWTD-UHFFFAOYSA-N

物化性质

• 沸点：
  248.2±50.0 °C(Predicted)
• 密度：
  1.39±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  57.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  4,5-二氢-4-氧代呋喃[3,2]吡啶 在 三氯氧磷 作用下， 生成 5H-furo[3,2-c]pyridine-4-thione
  参考文献：
  名称：

  Bourzat,J.-D.; Bisagni,E., Bulletin de la Societe Chimique de France, 1971, p. 1727 - 1730

  摘要：

  DOI：

文献信息

• 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE BETA-LACTAMASE INHIBITORS
  申请人：Cubist Pharmaceuticals, Inc.

  公开号：US20150031659A1

  公开（公告）日：2015-01-29

  β-Lactamase inhibitor compounds (BLIs) are disclosed, including compounds that have activity against class A, class C or class β-lactamases. Methods of manufacturing the BLIs, and uses of the compounds in the preparation of pharmaceutical compositions and antibacterial applications are also disclosed.

  本文披露了β-内酰胺酶抑制剂化合物（BLIs），其中包括对A类、C类或β-内酰胺酶具有活性的化合物。同时，还披露了制造BLIs的方法以及将这些化合物用于制备药物组合物和抗菌应用的用途。
• DNA ink—near-field absorption coupling for colorimetric detection, DNA ink, chromic photoswitches, and chromic molecular ruler
  申请人：Boise State University

  公开号：US11385235B2

  公开（公告）日：2022-07-12

  The nucleotides can then be polymerized into oligomers. The design of the oligomers will depend on the design of the overall architecture. Simple architectures may be designed by any methods. However, more complex architectures may be design using software, such as caDNAno (as described at cadnano.org/docs.html, and herein incorporated by reference), to minimize errors and time. The user may input the desired shape of the architecture into the software and once finalized, the software will provide the oligomer sequences of the bricks to create the desired architecture. The length of the oligomers may be from about 10 to about 10,000, or less than about 9,000, less than about 8,000, less than about 5,000 nucleotides in length. The length of the oligomer will be optimized for the type of architecture used.

  然后，核苷酸可以聚合成低聚物。低聚物的设计取决于整体结构的设计。简单的结构可以用任何方法设计。不过，更复杂的结构可以使用软件来设计，如 caDNAno（见 cadnano.org/docs.html，在此并入作为参考），以尽量减少误差和时间。用户可将所需的结构形状输入软件，一旦最终确定，软件将提供寡聚物序列，以创建所需的结构。寡聚体的长度可从约 10 到约 10,000，或小于约 9,000、小于约 8,000、小于约 5,000 个核苷酸。寡聚体的长度将根据所使用的结构类型进行优化。
• 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS
  申请人：Array Biopharma, Inc.

  公开号：EP2013204B1

  公开（公告）日：2015-02-18
• EXCITONIC QUANTUM COMPUTING MEDIATED BY CHROMOPHORE-EMBEDDED 1-, 2-, AND 3-DIMENSIONAL DNA SCAFFOLDS
  申请人：BOISE STATE UNIVERSITY

  公开号：US20190048036A1

  公开（公告）日：2019-02-14

  Using nucleotide architectures to very closely and precisely placed chromophores that produce quantum coherent excitons, biexcitons, and triexcitons upon excitement to create excitonic quantum wires, switching, and gates that would then form the basis of quantum computation. Creating the various excitons and controlling the timing of the excitons would be performed using light of the corresponding wavelength and polarization to stimulate the corresponding chromophores.
• DNA INK - NEAR-FIELD ABSORPTION COUPLING FOR COLORIMETRIC DETECTION, DNA INK, CHROMIC PHOTOSWITCHES, AND CHROMIC MOLECULAR RULER
  申请人：Boise State University

  公开号：US20190101543A1

  公开（公告）日：2019-04-04

  By bringing two chromophores close enough together such that near-filed interactions result in a change in absorption and can be measured by absorbance or visually observed with the eye. Examples of near-field interactions that could cause such an effect include electromagnetic dipole-dipole interactions and interactions resulting from orbital overlap as the chromophores are bought very proximate to one another. The change in absorption results in a color change and stronger absorption which produces a brighter color. The manner in which the multiple chromophores are placed close enough together is by using nucleotide self-assembly.