4-(3-Fluoro-4-methoxyphenyl)pyridine | 881419-06-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 4-(3-Fluoro-4-methoxyphenyl)pyridine
• CAS: 881419-06-3
• 化学式: C₁₂H₁₀FNO
• 分子量: 203.21
• InChiKey: SSQRKGMAMVYKQY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  22.1
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Novel pyridine compounds, process for their preparation and compositions containing them
  申请人：Pal Manojit

  公开号：US20060084644A1

  公开（公告）日：2006-04-20

  The present invention provides new heterocyclic compounds, particularly substituted pyridines, methods and compositions for making and using these heterocyclic compounds, and methods for treating a variety of diseases and disease states, including atherosclerosis, arthritis, restenosis, diabetic nephropathy, or dyslipidemia, or disease states mediated by the low expression of Perlecan.

  本发明提供了新的杂环化合物，特别是取代的吡啶，制备和使用这些杂环化合物的方法和组合物，以及治疗各种疾病和疾病状态的方法，包括动脉粥样硬化、关节炎、再狭窄、糖尿病肾病或血脂异常，或由Perlecan低表达介导的疾病状态。
• EP1805142A4
  申请人：——

  公开号：EP1805142A4

  公开（公告）日：2009-06-10
• NOVEL PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM
  申请人：Reddy US Therapeutics, Inc.

  公开号：EP1805142A2

  公开（公告）日：2007-07-11
• US7622486B2
  申请人：——

  公开号：US7622486B2

  公开（公告）日：2009-11-24
• [EN] NOVEL PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM<br/>[FR] COMPOSES A BASE DE PYRIDINE, LEUR PROCEDE DE PREPARATION ET COMPOSITIONS LES CONTENANT
  申请人：REDDY US THERAPEUTICS INC

  公开号：WO2006034474A2

  公开（公告）日：2006-03-30

  The present invention provides new heterocyclic compounds, particularly substituted pyridines, methods and compositions for making and using these heterocyclic compounds, and methods for treating a variety of diseases and disease states, including atherosclerosis, arthritis, restenosis, diabetic nephropathy, or dyslipidemia, or disease states mediated by the low expression of Perlecan.